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The action of medicinal animal horns on Escherichia coli growth investigated by microcalorimetry and chemometric analysis

  • Article
  • Physical Chemistry
  • Published:
Chinese Science Bulletin

Abstract

The action of Cornu Cervi Pantotrichum (CCP), Cornu Cervi (CC) and Cornu Saigae Tataricae (CST) on Escherichia coli growth were investigated using microcalorimetry to find the heat change regularity of microbial growth. The similarity of thermogenic curves and thermodynamics parameters were investigated as evaluation index, such as the growth rate constant in the first exponential phase (k 1), maximum power in the first exponential phase (P 1), maximum power in the secondary exponential phase (P 2), peak time in the first exponential phase (T 1), peak time in the stationary phase (T 2) and the total heat production in stage 1 (Q 1), and the total heat production in stage 2 (Q 2). Chemometric analysis was used as a reference for the bioactivity evaluation of medicinal animal horns. The results indicated that the similarity between CST and the control was smaller than that between CCP, CC and the control. Both CCP and CC could increase the heat in the microbial growth, whereas CST decreased it. The biotic thermal activity of different medicinal animal horns was objectively, qualitatively, and quantitatively evaluated by the similarity of thermogenic curves and thermodynamics parameters analysis.

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Authors and Affiliations

  1. Institute of Chinese Medicine, 302 Hospital of People’s Liberation Army, Beijing, 100039, China

    Dan Yan, YuMei Han, JiaoYang Luo, Ping Zhang, HuiYing Tang & XiaoHe Xiao

  2. Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China

    YuMei Han, JiaoYang Luo & Cheng Peng

  3. Chongqing Institute of Technology, Chongqing, 400050, China

    YuMei Han

Authors
  1. Dan Yan
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  2. YuMei Han
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  3. JiaoYang Luo
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  4. Ping Zhang
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  5. HuiYing Tang
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  6. Cheng Peng
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  7. XiaoHe Xiao
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Correspondence to XiaoHe Xiao.

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Yan, D., Han, Y., Luo, J. et al. The action of medicinal animal horns on Escherichia coli growth investigated by microcalorimetry and chemometric analysis. Chin. Sci. Bull. 55, 2945–2950 (2010). https://doi.org/10.1007/s11434-010-3348-4

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  • DOI: https://doi.org/10.1007/s11434-010-3348-4

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