Skip to main content
SpringerLink
Log in

Constituents of the roots of Ligularia dentata Hara

  • Natural Medicine Note
  • Published:
Journal of Natural Medicines Aims and scope Submit manuscript

Abstract

Nine known compounds, butyrospermol (1), lupeol (2), stigmast-4-en-3-one (3), stigmast-4-ene-3,6-dione (4), (+)-methyl abscisate (5), methyl indole-3-carboxylate (6), vanillin (7), methyl (E)-caffeate (8), and methyl (E)-ferulate (9), and two new compounds, methyl (E)-feruloylglycolate (10), and methyl-7,8-dihydro-(S)-7-methoxyferulate (11), have been isolated from the roots of Ligularia dentata Hara (Compositae). The structures were elucidated on the basis of spectral data.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Gao K, Jia Z (1998) Phenolic norsesquiterpenes from Ligularia dentata. Phytochemistry 49:167–169

    Article  CAS  Google Scholar 

  2. Baba H, Yaoita Y, Kikuchi M (2007) Sesquiterpenoids and lactone derivatives from Ligularia dentata. Helv Chim Acta (in press)

  3. Toyoda K, Yaoita Y, Kikuchi M (2005) Three new benzofuran derivatives from the roots of Ligularia stenocephala Matsum. et Koidz. Chem Pharm Bull 53:1555–1558

    Article  PubMed  CAS  Google Scholar 

  4. Toyoda K, Yaoita Y, Kikuchi M (2005) Chemical constituents of the genus Ligularia plants. II. Triterpenoids from the leaves and roots of Ligularia stenocephala (in Japanese). J Tohoku Pharm Univers 52:27–32

    CAS  Google Scholar 

  5. Gaspar EMM, Das Neves HJC (1993) Steroidal constituents from mature wheat straw. Phytochemistry 34:523–527

    Article  CAS  Google Scholar 

  6. Acemoglu M, Uebelhart P, Rey M, Eugster CH (1988) Synthese von enantiomerenreinen violaxanthinen und verwandten verbindungen. Helv Chim Acta 71:931–956

    Article  CAS  Google Scholar 

  7. Yue Q, Miller CJ, White JFJr, Richardson MD (2000) Isolation and characterization of fungal inhibitors from Epichloë festucae. J Agric Food Chem 48:4687–4692

    Article  PubMed  CAS  Google Scholar 

  8. Toyoda K, Yaoita Y, Kikuchi M (2006) Constituents of the leaves and roots of Ligularia stenocephala Matsum. et Koidz. J Nat Med 60:329–330

    Article  CAS  Google Scholar 

  9. Foti MC, Daquino C, Geraci C (2004) Electron-transfer reaction of cinnamic acids and their methyl esters with the DPPH radical in alcoholic solutions. J Org Chem 69:2309–2314

    Article  PubMed  CAS  Google Scholar 

  10. Miyazawa M, Okuno Y, Nakamura S, Kameoka H (1998) Suppression of SOS-inducing activity of chemical mutagens by cinnamic acid derivatives from Scrophulia ningpoensis in the Salmonella typhimurium TA1535/pSK1002 umu test. J Agric Food Chem 46:904–910

    Article  CAS  Google Scholar 

  11. Saleem M, Kim H, Jin C, Lee Y (2004) Antioxidant caffeic acid derivatives from leaves of Parthenocissus tricuspidata. Arch Pharm Res 27:300–304

    Article  PubMed  CAS  Google Scholar 

  12. Leu Y, Shi L, Damu AG (2003) Chemical constituents of Taraxacum formosanum. Chem Pharm Bull 51:599–601

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

We are grateful to Mr. S. Sato and Mr. T. Matsuki of this university for measurement of the mass and NMR spectra.

Author information

Authors and Affiliations

  1. Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981-8558, Japan

    Hitomi Baba, Yasunori Yaoita & Masao Kikuchi

Authors
  1. Hitomi Baba
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yasunori Yaoita
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Masao Kikuchi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Masao Kikuchi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Baba, H., Yaoita, Y. & Kikuchi, M. Constituents of the roots of Ligularia dentata Hara. J Nat Med 61, 472–473 (2007). https://doi.org/10.1007/s11418-007-0156-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11418-007-0156-5

Keywords

Search

Navigation