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Constituents of the leaves and roots of Ligularia stenocephala MATSUM. et KOIDZ.

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Abstract

Constituents of the leaves and roots of Ligularia stenocephala MATSUM. et KOIDZ. (Compositae) were investigated. Three compounds, (2E,6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaen-1-ol, (3E,6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyl-3,6,10,14,18,22-tetracosahexaen-2-ol and neophytadiene, were isolated from the leaves of L. stenocephala. Six compounds, 5-acetyl-6-hydroxy-2α-isopropenyl-3β-methoxy-2,3H-benzofuran, 3β-acetoxy-6-acetyl-5-hydroxy-2α-isopropenyl-2,3H-benzofuran, p-hydroxybenzaldehyde, vanillin, 4-hydroxyacetophenone and 4-hydroxy-3-methoxyacetophenone, were isolated from the roots of L. stenocephala. The structures were determined on the basis of spectral data.

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Acknowledgments

We are grateful to Mr. S. Sato and Mr. T. Matsuki of this university for measurement of the mass and NMR spectra.

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Authors and Affiliations

  1. Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981-8558, Japan

    Kazuki Toyoda, Yasunori Yaoita & Masao Kikuchi

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  1. Kazuki Toyoda
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  2. Yasunori Yaoita
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  3. Masao Kikuchi
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Correspondence to Masao Kikuchi.

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Toyoda, K., Yaoita, Y. & Kikuchi, M. Constituents of the leaves and roots of Ligularia stenocephala MATSUM. et KOIDZ.. J Nat Med 60, 329–330 (2006). https://doi.org/10.1007/s11418-006-0008-8

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  • DOI: https://doi.org/10.1007/s11418-006-0008-8

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