Abstract
Recently, the high prevalence of hypertension (HTN) has caused serious disease burden. Previous studies mostly focused on the separate association between outdoor or indoor air pollution and HTN, and did not explore their possible interaction with HTN. To explore this issue, this study investigated the relationship between indoor and outdoor air pollution and HTN and their possible interactions among adult residents in 14 rural areas in eastern China. The generalized linear model (GLM) and interplot model were used to evaluate the separate effects and potential interaction of outdoor or indoor air pollutants on HTN. In separate analyses, we found a significant positive association between outdoor and indoor air pollution and HTN, and a significant negative association between range hood use and HTN. In the interaction analysis, outdoor air pollution could significantly enhance the positive effects of indoor air pollution on HTN. In addition, PM2.5 and O3 could significantly reduce the protective effect of range hoods use on HTN. Finally, we found that females were more susceptible to both indoor and outdoor air pollution.
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We would like to thank all the subjects who participated in this research. This work was supported by The Project for Top Disciplinary Talents of Majors in Universities of Anhui Province [grant numbers gxbjZD09].
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This work was supported by The Project for Top Disciplinary Talents of Majors in Universities of Anhui Province [grant numbers gxbjZD09].
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Guoao Li: conceptualization, methodology, software, writing—original draft, formal analysis. Huanhuan Lu: conceptualization, methodology, software, writing—original draft. Wenlei Hu: writing—review and editing. Jianjun Liu: data curation. Mingjun Hu: data curation, formal analysis. Jialiu He: data curation, formal analysis. Fen Huang: conceptualization, methodology, writing—review and editing, project administration, funding acquisition.
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Li, G., Lu, H., Hu, W. et al. Outdoor air pollution enhanced the association between indoor air pollution exposure and hypertension in rural areas of eastern China. Environ Sci Pollut Res 29, 74909–74920 (2022). https://doi.org/10.1007/s11356-022-21127-8
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DOI: https://doi.org/10.1007/s11356-022-21127-8