Skip to main content

Advertisement

SpringerLink
Log in

Emerging contaminants in Brazilian aquatic environment: identifying targets of potential concern based on occurrence and ecological risk

  • Research Article
  • Published:
Environmental Science and Pollution Research Aims and scope Submit manuscript

Abstract

Although studies have shown the presence of Contaminants of Emerging Concern (CECs) in the Brazilian environment in recent decades, several biological effects on the aquatic ecosystem are unknown. Brazil is the fifth largest country in extension in the world, and its wide territory presents geographic regions with diverse demographic and economic characteristics. In order to identify targets of potential concern based on occurrence and ecological risk, available data from previous studies were examined to conduct environmental risk analysis and provide a ranking of CECs in Brazilian aquatic environment based on environmental concentration measured in the last 10 years. The results indicate that 17α-ethynylestradiol, 17ß-estradiol, acetaminophen, Bisphenol A, caffeine, diclofenac, ibuprofen, methylparaben, sulfamethoxazole and triclosan are the CECs that represent the greatest threats to the Brazilian environment. Therefore, these contaminants should be considered as a priority in future monitoring studies. Besides, identification of target monitoring compounds can facilitate the selection of pollutant candidates in future legislations.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Availability of data and materials

All data generated or analyzed during this study are included in this published article.

References

  • Agunbiade FO, Moodley B (2016) Occurrence and distribution pattern of acidic pharmaceuticals in surface water, wastewater, and sediment of the Msunduzi River, Kwazulu-Natal, South Africa. Environ. Toxicol. Chem. 35:36–46

    Article  CAS  Google Scholar 

  • Aitken M, Kleinrock M (2015) Global medicines use in 2020: outlook and implications. USA: Parsippany, New Jersey

  • Almeida Â, Solé M, Soares AM, Freitas R (2020) Anti-inflammatory drugs in the marine environment: Bioconcentration, metabolism and sub-lethal effects in marine bivalves. Environ. Pollut. 263:114442

    Article  CAS  Google Scholar 

  • Aragão RBDA, Semensatto D, Calixto LA, Labuto G (2020) Pharmaceutical market, environmental public policies and water quality: the case of the São Paulo Metropolitan Region. Brazil. Reports in Public Health 36:e00192319

    Google Scholar 

  • Arsand JB, Hoff RB, Jank L, Bussamara R, Dallegrave A, Bento FM, Kmetzsch L, Falção DA, Peralba MDCR, De Araujo Gomes A (2020) Presence of antibiotic resistance genes and its association with antibiotic occurrence in Dilúvio River in southern Brazil. Sci. Total Environ. 738:139781

    Article  CAS  Google Scholar 

  • Ashfaq M, Li Y, Rehman MSU, Zubair M, Mustafa G, Nazar MF, Yu C-P, Sun Q (2019) Occurrence, spatial variation and risk assessment of pharmaceuticals and personal care products in urban wastewater, canal surface water, and their sediments: a case study of Lahore, Pakistan. Sci. Total Environ. 688:653–663

    Article  CAS  Google Scholar 

  • Barros ALC, Schmidt FF, De Aquino SF, Afonso RJDCF (2018) Determination of nine pharmaceutical active compounds in surface waters from Paraopeba River Basin in Brazil by LTPE-HPLC-ESI-MS/MS. Environ. Sci. Pollut. Res. 25:19962–19974

    Article  Google Scholar 

  • Bedoya-Ríos DF, Lara-Borrero JA, Duque-Pardo V, Madera-Parra CA, Jimenez EM, Toro AF (2018) Study of the occurrence and ecosystem danger of selected endocrine disruptors in the urban water cycle of the city of Bogotá, Colombia. J Environ Sci Health A 53:317–325

    Article  Google Scholar 

  • Brasil, Agência Nacional de Vigilancia Sanitária - ANVISA. Anuário Estatístico do Mercado Farmacêutico (2018) Disponível em: http://portal.anvisa.gov.br/documents/374947/3413536/Anu%C3%A1rio+Estat%C3%ADstico+do+Mercado+Farmac%C3%AAutico+-+2017/3179a522-1af4-4b4c-8014-cc25a90fb5a7

  • Brasil, A. N. D. V. S. RDC N. 29, June 1, 2012 (RDC N. 29 de 1 de junho de 2012). DOU, (2012), pp. 4.

  • Caldas SS, Bolzan CM, Guilherme JR, Silveira MAK, Escarrone ALV, Primel EG (2013) Determination of pharmaceuticals, personal care products, and pesticides in surface and treated waters: method development and survey. Environ. Sci. Polluti. Res. 20:5855–5863

    Article  CAS  Google Scholar 

  • Caldas SS, Arias JLO, Rombaldi C, Mello LL, Cerqueira MB, Martins AF, Primel EG (2019) Occurrence of pesticides and PPCPs in surface and drinking water in Southern Brazil: data on 4-year monitoring. J. Braz. Chem. Soc. 30:71–80

    CAS  Google Scholar 

  • Calderón-Moreno GM, Vergara-Sánchez J, Saldarriaga-Noreña H, García-Betancourt ML, Domínguez-Patiño ML, Moeller-Chávez GE, Ronderos-Lara JG, Arias-Montoya MI, Montoya-Balbas IJ, Murillo-Tovar MA (2019) Occurrence and risk assessment of steroidal hormones and phenolic endocrine disrupting compounds in surface water in Cuautla River, Mexico. Water 11:2628

    Article  Google Scholar 

  • Campanha MB, Awan AT, De Sousa DN, Grosseli GM, Mozeto AA, Fadini PS (2015) A 3-year study on occurrence of emerging contaminants in an urban stream of São Paulo State of Southeast Brazil. Environ. Sci. Polluti. Res. 22:7936–7947

    Article  CAS  Google Scholar 

  • Carmona E, Andreu V, Picó Y (2017) Multi-residue determination of 47 organic compounds in water, soil, sediment and fish—Turia River as case study. J. Pharm. Biomed. 146:117–125

    Article  CAS  Google Scholar 

  • Chaves MJS, Barbosa SC, Malinowski MDM, Volpato D, Castro ÍB, Franco TCRS, Primel EG (2020) Pharmaceuticals and personal care products in a Brazilian wetland of international importance: occurrence and environmental risk assessment. Sci. Total Environ. 734:139374

    Article  CAS  Google Scholar 

  • Chen S, Gan Z, Li Z, Li Y, Ma X, Chen M, Qu B, Ding S, Su S (2021) Occurrence and risk assessment of anthelmintics in Tuojiang River in Sichuan. China. Ecotox Environ Safe 220:112360

    Article  CAS  Google Scholar 

  • Chiriac FL, Paun I, Pirvu F, Iancu V, Galaon T (2021) Distribution, removal efficiencies and environmental risk assessment of benzophenone and salicylate UV filters in WWTPs and surface waters from Romania. New J. Chem 45:2478–2487

    Article  CAS  Google Scholar 

  • Comtois-Marotte S, Chappuis T, Duy SV, Gilbert N, Lajeunesse A, Taktek S, Desrosiers M, Veilleux É, Sauvé S (2017) Analysis of emerging contaminants in water and solid samples using high resolution mass spectrometry with a Q Exactive orbital ion trap and estrogenic activity with YES-assay. Chemosphere 166:400–411

    Article  CAS  Google Scholar 

  • Cunha, D. L.,Muylaert, S.,Nascimento, M. T.,Felix, L. C.,Gomes, G.,Bila, D. M., Fonseca, E. M. Occurrence of emerging contaminants and analysis of oestrogenic activity in the water and sediments from two coastal lagoons in south-eastern Brazil. Mar. Freshwater Res., 72 (2020), pp. A-O.

  • Dafouz R, Cáceres N, Rodríguez-Gil JL, Mastroianni N, De Alda ML, Barceló D, De Miguel ÁG, Valcárcel Y (2018) Does the presence of caffeine in the marine environment represent an environmental risk? A regional and global study. Sci. Total Environ 615:632–642

    Article  CAS  Google Scholar 

  • Dai G, Wang B, Huang J, Dong R, Deng S, Yu G (2015) Occurrence and source apportionment of pharmaceuticals and personal care products in the Beiyun River of Beijing. China. Chemosphere 119:1033–1039

    Article  CAS  Google Scholar 

  • Deere JR, Moore S, Ferrey M, Jankowski MD, Primus A, Convertino M, Servadio JL, Phelps NB, Hamilton MC, Chenaux-Ibrahim Y (2020) Occurrence of contaminants of emerging concern in aquatic ecosystems utilized by Minnesota tribal communities. Sci. Total Environ. 724:138057

    Article  CAS  Google Scholar 

  • Eur EC (2020) Commission Implementing Decision (EU) 2020/1161 of 4 August 2020 Establishing a watch list of substances for union-wide monitoring in the field of water policy pursuant to directive 2008/105/EC of the European Parliament and of the council. Off. J. Eur. Union. 257:32–35

    Google Scholar 

  • Eur, E. C.-. Technical Guidance Document on Risk Assessment in support of Commission Directive 93/67/EEC on Risk Assessment for new notified substances. Ispra (IT): European Commission Joint Research Centre. EUR, 20418 (2003), pp.

  • Eur, E. C. Directive 2013/39/EU of the European Parliament and of the Council of 12 August 2013 amending Directives 2000/60/EC and 2008/105/EC as regards priority substances in the field of water policy. Off. J. Eur. Union, 226 (2013), pp. 1-17.

  • Farias MR, Leite SN, Tavares NUL, Oliveira MA, Arrais PSD, Bertoldi AD, Pizzol TDSD, Luiza VL, Ramos LR, Mengue SS (2016) Use of and access to oral and injectable contraceptives in Brazil. Revista de Saúde Pública 50:14s

    Article  Google Scholar 

  • Feo ML, Bagnati R, Passoni A, Riva F, Manta DS, Sprovieri M, Traina A, Zuccato E, Castiglioni S (2020) Pharmaceuticals and other contaminants in waters and sediments from Augusta Bay (southern Italy). Sci. Total Environ. 739:139827

    Article  CAS  Google Scholar 

  • Fontes MK, De Campos BG, Cortez FS, Pusceddu FH, Moreno BB, Maranho LA, Lebre DT, Guimarães LL, Pereira CDS (2019) Seasonal monitoring of cocaine and benzoylecgonine in a subtropical coastal zone (Santos Bay, Brazil). Mar. Pollut. Bull. 149:110545

    Article  CAS  Google Scholar 

  • Galinaro CA, Pereira FM, Vieira EM (2015) Determination of parabens in surface water from Mogi Guaçu River (São Paulo, Brazil) using dispersive liquid-liquid microextraction based on low density solvent and LC-DAD. J. Braz. Chem. Soc. 26:2205–2213

    CAS  Google Scholar 

  • Gorga M, Insa S, Petrovic M, Barceló D (2015) Occurrence and spatial distribution of EDCs and related compounds in waters and sediments of Iberian rivers. Sci. Total Environ 503:69–86

    Article  Google Scholar 

  • Griffero L, Alcántara-Durán J, Alonso C, Rodríguez-Gallego L, Moreno-González D, García-Reyes JF, Molina-Díaz A, Pérez-Parada A (2019) Basin-scale monitoring and risk assessment of emerging contaminants in South American Atlantic coastal lagoons. Sci. Total Environ 697:134058

    Article  CAS  Google Scholar 

  • Guruge KS, Goswami P, Tanoue R, Nomiyama K, Wijesekara R, Dharmaratne TS (2019) First nationwide investigation and environmental risk assessment of 72 pharmaceuticals and personal care products from Sri Lankan surface waterways. Sci Total Environ 690:683–695

    Article  CAS  Google Scholar 

  • Guzel, E. Y.,Cevik, F., Daglioglu, N. Determination of pharmaceutical active compounds in Ceyhan River, Turkey: seasonal, spatial variations and environmental risk assessment. Hum Ecol Risk Assess, 25 (2019), pp. 1980-1995.

  • Ibge, B. I. B. D. G. E. E.-. Projeção da população do Brasil e das Unidades da Federação. (2020). Disponível em: https://www.ibge.gov.br/apps/populacao/projecao/.

  • Ide AH, Osawa RA, Marcante LO, Da Costa Pereira J, De Azevedo JCR (2017) Occurrence of pharmaceutical products, female sex hormones and caffeine in a subtropical region in Brazil. CLEAN–Soil, Air, Water 45:1700334

    Article  Google Scholar 

  • Ilyas H, Van Hullebusch ED (2020) A review on the occurrence, fate and removal of steroidal hormones during treatment with different types of constructed wetlands. J. Environ. Chem. Eng. 8:103793

    Article  CAS  Google Scholar 

  • Inam E, Offiong N-A, Kang S, Yang P, Essien J (2015) Assessment of the occurrence and risks of emerging organic pollutants (EOPs) in Ikpa River Basin freshwater ecosystem, Niger Delta-Nigeria. Bull. Environ. Contam. Toxicol. 95:624–631

    Article  CAS  Google Scholar 

  • Ismail NAH, Wee SY, Kamarulzaman NH, Aris AZ (2019) Quantification of multi-classes of endocrine-disrupting compounds in estuarine water. Environ. Pollut 249:1019–1028

    Article  CAS  Google Scholar 

  • Jank L, Hoff RB, Costa FJD, Pizzolato TM (2014) Simultaneous determination of eight antibiotics from distinct classes in surface and wastewater samples by solid-phase extraction and high-performance liquid chromatography–electrospray ionisation mass spectrometry. Int. J. Environ. Anal. Chem. 94:1013–1037

    Article  CAS  Google Scholar 

  • Kairigo P, Ngumba E, Sundberg L-R, Gachanja A, Tuhkanen T (2020) Occurrence of antibiotics and risk of antibiotic resistance evolution in selected Kenyan wastewaters, surface waters and sediments. Sci. Total Environ. 720:137580

    Article  CAS  Google Scholar 

  • Kosma CI, Lambropoulou DA, Albanis TA (2014) Investigation of PPCPs in wastewater treatment plants in Greece: occurrence, removal and environmental risk assessment. Sci Total Environ 466:421–438

    Article  Google Scholar 

  • Kötke D, Gandrass J, Xie Z, Ebinghaus R (2019) Prioritised pharmaceuticals in German estuaries and coastal waters: Occurrence and environmental risk assessment. Environ. Pollut 255:113161

    Article  Google Scholar 

  • Kovalakova P, Cizmas L, Mcdonald TJ, Marsalek B, Feng M (2020) Sharma. V. K. Occurrence and toxicity of antibiotics in the aquatic environment: a review. Chemosphere 251:126351

    CAS  Google Scholar 

  • Kumar M, Ram B, Honda R, Poopipattana C, Canh VD, Chaminda T, Furumai H (2019) Concurrence of antibiotic resistant bacteria (ARB), viruses, pharmaceuticals and personal care products (PPCPs) in ambient waters of Guwahati, India: urban vulnerability and resilience perspective. Sci. Total Environ. 693:133640

    Article  CAS  Google Scholar 

  • Li S, Shi W, Li H, Xu N, Zhang R, Chen X, Sun W, Wen D, He S, Pan J (2018) Antibiotics in water and sediments of rivers and coastal area of Zhuhai City, Pearl River estuary, south China. Sci. Total Environ. 636:1009–1019

    Article  CAS  Google Scholar 

  • Lin T, Yu S, Chen W (2016) Occurrence, removal and risk assessment of pharmaceutical and personal care products (PPCPs) in an advanced drinking water treatment plant (ADWTP) around Taihu Lake in China. Chemosphere 152:1–9

    Article  CAS  Google Scholar 

  • Liu W-R, Zhao J-L, Liu Y-S, Chen Z-F, Yang Y-Y, Zhang Q-Q, Ying G-G (2015) Biocides in the Yangtze River of China: spatiotemporal distribution, mass load and risk assessment. Environ Pollut 200:53–63

    Article  CAS  Google Scholar 

  • Liu J, Zhang L, Lu G, Jiang R, Yan Z, Li Y (2020a) Occurrence, toxicity and ecological risk of Bisphenol A analogues in aquatic environment—a review. Ecotox. Environ. Safe. 208:111481

    Article  Google Scholar 

  • Liu N, Jin X, Feng C, Wang Z, Wu F, Johnson AC, Xiao H, Hollert H, Giesy JP (2020b) Ecological risk assessment of fifty pharmaceuticals and personal care products (PPCPs) in Chinese surface waters: a proposed multiple-level system. Environ. Int. 136:105454

    Article  CAS  Google Scholar 

  • Locatelli MAF, Sodré FF, Jardim WF (2011) Determination of antibiotics in Brazilian surface waters using liquid chromatography–electrospray tandem mass spectrometry. Arch. Environ. Contam. Toxicol 60:385–393

    Article  CAS  Google Scholar 

  • Lopes VSA, Riente RR, Da Silva AA, Torquilho DF, Da Silva Carreira R, Da Costa Marques MR (2016) Development of a solid-phase extraction system modified for preconcentration of emerging contaminants in large sample volumes from rivers of the lagoon system in the city of Rio de Janeiro, Brazil. Mar. Pollut. Bull. 110:572–577

    Article  CAS  Google Scholar 

  • López-Doval JC, Montagner CC, De Alburquerque AF, Moschini-Carlos V, Umbuzeiro G, Pompêo M (2017) Nutrients, emerging pollutants and pesticides in a tropical urban reservoir: spatial distributions and risk assessment. Sci. Total Environ 575:1307–1324

    Article  Google Scholar 

  • López-Pacheco IY, Silva-Núñez A, Salinas-Salazar C, Arévalo-Gallegos A, Lizarazo-Holguin LA, Barceló D, Iqbal HM, Parra-Saldívar R (2019) Anthropogenic contaminants of high concern: existence in water resources and their adverse effects. Sci. Total Environ 690:1068–1088

    Article  Google Scholar 

  • Montagner CC, Jardim WF (2011) Spatial and seasonal variations of pharmaceuticals and endocrine disruptors in the Atibaia River, São Paulo State (Brazil). J. Braz. Chem. Soc. 22:1452–1462

    Article  CAS  Google Scholar 

  • Montagner CC, Jardim WF, Von Der Ohe PC, Umbuzeiro GA (2014) Occurrence and potential risk of triclosan in freshwaters of São Paulo, Brazil—the need for regulatory actions. Environ. Sci. Polluti. Res. 21:1850–1858

    Article  CAS  Google Scholar 

  • Montagner CC, Sodré FF, Acayaba RD, Vidal C, Campestrini I, Locatelli MA, Pescara IC, Albuquerque AF, Umbuzeiro GA, Jardim WF (2019) Ten years-snapshot of the occurrence of emerging contaminants in drinking, surface and ground waters and wastewaters from São Paulo State. Brazil. J. Braz. Chem. Soc. 30:614–632

    CAS  Google Scholar 

  • Monteiro MA, Spisso BF, Ferreira RG, Pereira MU, Grutes JV, De Andradec BR, D’avila LA (2018) Development and validation of liquid chromatography-tandem mass spectrometry methods for determination of beta-lactams, macrolides, fluoroquinolones, sulfonamides and tetracyclines in surface and drinking water from Rio de Janeiro, Brazil. J. Braz. Chem. Soc 29:801–813

    CAS  Google Scholar 

  • Moreira M, Aquino S, Coutrim M, Silva J, Afonso R (2011) Determination of endocrine-disrupting compounds in waters from Rio das Velhas, Brazil, by liquid chromatography/high resolution mass spectrometry (ESI-LC-IT-TOF/MS). Environ. Technol. 32:1409–1417

    Article  CAS  Google Scholar 

  • Nannou CI, Kosma CI, Albanis TA (2015) Occurrence of pharmaceuticals in surface waters: analytical method development and environmental risk assessment. Inter J Environ Anal Chem 95:1242–1262

    Article  CAS  Google Scholar 

  • Nantaba F, Palm W-U, Wasswa J, Bouwman H, Kylin H, Kümmerer K (2021) Temporal dynamics and ecotoxicological risk assessment of personal care products, phthalate ester plasticizers, and organophosphorus flame retardants in water from Lake Victoria, Uganda. Chemosphere 262:127716

    Article  CAS  Google Scholar 

  • Ngo TH, Van D-A, Le Tran H, Nakada N, Tanaka H, Huynh TH (2020) Occurrence of pharmaceutical and personal care products in Cau River, Vietnam. Environ. Sci. Pollut. Res. Int. 28:12082–12091

    Article  Google Scholar 

  • Norman, N. NORMAN Suspect List Exchange. (2019).

  • Patel M, Kumar R, Kishor K, Mlsna T, Pittman CU Jr, Mohan D (2019) Pharmaceuticals of emerging concern in aquatic systems: chemistry, occurrence, effects, and removal methods. Chem. Rev. 119:3510–3673

    Article  CAS  Google Scholar 

  • Pemberthy D, Padilla Y, Echeverri A, Peñuela GA (2020) Monitoring pharmaceuticals and personal care products in water and fish from the Gulf of Urabá, Colombia. Heliyon 6:e04215

    Article  Google Scholar 

  • Pereira CDS, Maranho LA, Cortez FS, Pusceddu FH, Santos AR, Ribeiro DA, Cesar A, Guimarães LL (2016) Occurrence of pharmaceuticals and cocaine in a Brazilian coastal zone. Sci. Total Environ. 548:148–154

    Article  Google Scholar 

  • Pivetta GG, Gastaldini MDCC (2019) Presence of emerging contaminants in urban water bodies in southern Brazil. J. Water Health 17:329–337

    Article  Google Scholar 

  • Pompei CME, Campos LC, Da Silva BF, Fogo JC, Vieira EM (2019) Occurrence of PPCPs in a Brazilian water reservoir and their removal efficiency by ecological filtration. Chemosphere 226:210–219

    Article  CAS  Google Scholar 

  • Reichert G, Mizukawa A, Antonelli J, Goulart FDAB, Filippe TC, De Azevedo JCR (2020) Determination of parabens, triclosan, and lipid regulators in a subtropical urban river: effects of urban occupation. Water Air Soil Pollut 231:1–11

    Article  Google Scholar 

  • Reis EO, Foureaux AFS, Rodrigues JS, Moreira VR, Lebron YA, Santos LV, Amaral MC, Lange LC (2019) Occurrence, removal and seasonal variation of pharmaceuticals in Brasilian drinking water treatment plants. Environ. Pollut. 250:773–781

    Article  CAS  Google Scholar 

  • Rigueto CVT, Nazari MT, De Souza CF, Cadore JS, Brião VB, Piccin JS (2020) Alternative techniques for caffeine removal from wastewater: an overview of opportunities and challenges. J. Water Proc. Engineering 35:101231

    Article  Google Scholar 

  • Rivera-Jaimes JA, Postigo C, Melgoza-Alemán RM, Aceña J, Barceló D, De Alda ML (2018) Study of pharmaceuticals in surface and wastewater from Cuernavaca, Morelos, Mexico: occurrence and environmental risk assessment. Sci. Total Environ 613:1263–1274

    Article  Google Scholar 

  • Roveri, V.,Guimarães, L. L.,Toma, W., Correia, A. T. (2020) Occurrence and risk assessment of pharmaceuticals and cocaine around the coastal submarine sewage outfall in Guarujá, São Paulo State, Brazil. Environ. Sci. Pollut. Res, pp. 1-17

  • Santos MMD, Brehm FDA, Filippe TC, Knapik HG, Azevedo JCRD (2016) Occurrence and risk assessment of parabens and triclosan in surface waters of southern Brazil: a problem of emerging compounds in an emerging country. RBRH 21:603–617

    Article  Google Scholar 

  • Santos AV, Couto CF, Lebron YAR, Moreira VR, Foureaux AFS, Reis EO, de Souza Santos LV, De Andrade LH, Amaral MCS, Lange LC (2020) Occurrence and risk assessment of pharmaceutically active compounds in water supply systems in Brazil. Sci. Total Environ. 746:141011

    Article  CAS  Google Scholar 

  • Sharma BM, Bečanová J, Scheringer M, Sharma A, Bharat GK, Whitehead PG, Klánová J, Nizzetto L (2019) Health and ecological risk assessment of emerging contaminants (pharmaceuticals, personal care products, and artificial sweeteners) in surface and groundwater (drinking water) in the Ganges River Basin, India. Sci. Total Environ. 646:1459–1467

    Article  CAS  Google Scholar 

  • Silva CP, Emídio ES, De Marchi MRR (2015) The occurrence of UV filters in natural and drinking water in São Paulo State (Brazil). Environ. Sci. Pollut. Res. 22:19706–19715

    Article  Google Scholar 

  • Silveira MAK, Caldas SS, Guilherme JR, Costa FP, Guimarães BDS, Cerqueira MB, Soares BM, Primel EG (2013) Quantification of pharmaceuticals and personal care product residues in surface and drinking water samples by SPE and LC-ESI-MS/MS. Journal of the Brazilian Chemical Society 24:1385–1395

    CAS  Google Scholar 

  • Singh V, Suthar S (2021) Occurrence, seasonal variations, and ecological risk of pharmaceuticals and personal care products in River Ganges at two holy cities of India. Chemosphere 268:129331

    Article  CAS  Google Scholar 

  • Sousa DNR, Mozeto AA, Carneiro RL, Fadini PS (2014) Electrical conductivity and emerging contaminant as markers of surface freshwater contamination by wastewater. Sci. Total Environ 484:19–26

    Article  Google Scholar 

  • Sousa DNR, Mozeto AA, Carneiro RL, Fadini PS (2018) Spatio-temporal evaluation of emerging contaminants and their partitioning along a Brazilian watershed. Environ. Sci. Polluti. Res. 25:4607–4620

    Article  Google Scholar 

  • Souza M, Rizzetti T, Francesquett J, Prestes O, Zanella R (2018) Bar adsorptive microextraction (BAμE) with a polymeric sorbent for the determination of emerging contaminants in water samples by ultra-high performance liquid chromatography with tandem mass spectrometry. Anal. Methods 10:697–705

    Article  Google Scholar 

  • Sposito JC, Montagner CC, Casado M, Navarro-Martín L, Solórzano JCJ, Piña B, Grisolia AB (2018) Emerging contaminants in Brazilian rivers: occurrence and effects on gene expression in zebrafish (Danio rerio) embryos. Chemosphere 209:696–704

    Article  CAS  Google Scholar 

  • Starling MCV, Amorim CC, Leão MMD (2019) Occurrence, control and fate of contaminants of emerging concern in environmental compartments in Brazil. J. Hazard. Mater. 372:17–36

    Article  CAS  Google Scholar 

  • Sun Q, Li Y, Li M, Ashfaq M, Lv M, Wang H, Hu A, Yu C-P (2016) PPCPs in Jiulong River estuary (China): spatiotemporal distributions, fate, and their use as chemical markers of wastewater. Chemosphere 150:596–604

    Article  CAS  Google Scholar 

  • Thiebault T (2020) Sulfamethoxazole/Trimethoprim ratio as a new marker in raw wastewaters: a critical review. Sci. Total Environ. 715:136916

    Article  CAS  Google Scholar 

  • Thomas KV, Da Silva FMA, Langford K, De Souza ADL, Nizzeto L, Waichman A (2014) Screening for selected human pharmaceuticals and cocaine in the urban streams of Manaus, Amazonas, Brazil. J. Am. Water Resour. As 50:302–308

    Article  CAS  Google Scholar 

  • Torres NH, Aguiar MM, Ferreira LFR, Américo JHP, Machado ÂM, Cavalcanti EB, Tornisielo VL (2015) Detection of hormones in surface and drinking water in Brazil by LC-ESI-MS/MS and ecotoxicological assessment with Daphnia magna. Environ. Monitor. Asses. 187:379

    Article  Google Scholar 

  • Voloshenko-Rossin A, Gasser G, Cohen K, Gun J, Cumbal-Flores L, Parra-Morales W, Sarabia F, Ojeda F, Lev O (2015) Emerging pollutants in the Esmeraldas watershed in Ecuador: discharge and attenuation of emerging organic pollutants along the San Pedro–Guayllabamba–Esmeraldas rivers. Environ. Sci. Proces. Impacts 17:41–53

    Article  CAS  Google Scholar 

  • Wang C, He J, Xu T, Han H, Zhu Z, Meng L, Pang Q, Fan R (2021) Bisphenol A (BPA), BPS and BPB-induced oxidative stress and apoptosis mediated by mitochondria in human neuroblastoma cell lines. Ecotoxicology and Environmental Safety 207:111299

    Article  CAS  Google Scholar 

  • Wu M-H, Xie D-G, Xu G, Sun R, Xia X-Y, Liu W-L, Tang L (2017) Benzophenone-type UV filters in surface waters: an assessment of profiles and ecological risks in Shanghai, China. Ecotox Environ Safe 141:235–241

    Article  CAS  Google Scholar 

  • Zheng Y, Lu G-H, Shao P-W, Piao H-T, Gai N, Rao Z, Zhao Q-S, Yang Y-L (2020) Source tracking and risk assessment of pharmaceutical and personal care products in surface waters of Qingdao, China, with emphasis on influence of animal farming in rural areas. Arch Environ Con Tox 78:579–588

    Article  CAS  Google Scholar 

  • Zhong R, Zou H, Gao J, Wang T, Bu Q, Wang Z-L, Hu M, Wang Z (2021) A critical review on the distribution and ecological risk assessment of steroid hormones in the environment in China. Sci Total Environ 786:147452

    Article  CAS  Google Scholar 

Download references

Funding

The authors acknowledge the financial support granted by the Brazilian agencies FAPERGS, CAPES (Finance Code 001), CNPq (process number 405802/2016-1), FINEP and fellowships granted by CAPES. Primel, E. G. received a productivity research fellowship from the CNPq (DT 305716/2020-4).

Author information

Authors and Affiliations

  1. Post-Graduate Program in Technological and Environmental Chemistry, Escola de Química e Alimentos, Laboratório de Análise de Compostos Orgânicos e Metais (LACOM), Universidade Federal do Rio Grande, Av Itália, km 8, Rio Grande, RS, 96201-900, Brazil

    Marisa de Jesus Silva Chaves, Sergiane Caldas Barbosa & Ednei Gilberto Primel

Authors
  1. Marisa de Jesus Silva Chaves
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sergiane Caldas Barbosa
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ednei Gilberto Primel
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

MJSC Conceptualization, performed the literature search and data analysis, roles/writing—original draft. SCB Writing—review and editing, supervision. EGP Writing—review and editing, project administration.

Corresponding author

Correspondence to Ednei Gilberto Primel.

Ethics declarations

Ethics approval

Not applicable.

Consent to participate

All authors participated in this work.

Consent for publication

All authors agree to publish.

Competing interests

The authors declare no competing interests.

Additional information

Responsible Editor: Ester Heath

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

ESM 1

(DOCX 16 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chaves, M.d.J.S., Barbosa, S.C. & Primel, E.G. Emerging contaminants in Brazilian aquatic environment: identifying targets of potential concern based on occurrence and ecological risk. Environ Sci Pollut Res 28, 67528–67543 (2021). https://doi.org/10.1007/s11356-021-15245-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11356-021-15245-y

Keywords

Search

Navigation