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Molecular analysis and characterization of swine and human influenza viruses isolated in Hungary in 2006–2007

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Abstract

In order to provide additional information to the epidemiological situation in Middle Europe and open further possibilities to investigate the transmission of influenza viruses between species, the viral genomes of three influenza A virus isolates (one human and two swine) collected from North-East Hungary in 2006–2007 have been fully sequenced and characterized. The sequence analysis reveals strong geographical relationships between the internal genes of the two swine viruses; the human isolate shows strict conservation to recent H1N1 strains, while the swine strains demonstrate and reflect a mixed avian–human origin, a characteristic of European swine influenza viruses. No evidence of interspecies interaction has been found among the studied isolates.

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Acknowledgments

This work was partly supported by the Swedish Emergency Management Agency, the EPIZONE project (Network of Excellence for Epizootic Disease Diagnosis and Control, FP6-2004-Food-3-A), the Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (Formas 221-2006-2169 and Formas 2007-3040-9229-19) projects, and the FLUTEST EU project (Contract No.: 044429).

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Authors and Affiliations

  1. Department of Physiology, University of Kentucky College of Medicine, 138 Leader Ave., 800 Rose St., Lexington, KY, 40506-9983, USA

    Péter Gyarmati

  2. Department of Virology, National Veterinary Institute and Swedish Agricultural University, Ulls väg 2B, Uppsala, 751 89, Sweden

    Péter Gyarmati, Giorgi Metreveli, Sándor Belák & István Kiss

  3. Department of Microbiology, Central Agricultural Office, Veterinary Diagnostic Directorate, Bornemissza u. 3-7, Debrecen, 4031, Hungary

    Sándor Kecskeméti & István Kiss

  4. Department of Respiratory Viruses, National Center for Epidemiology, Gyáli u. 2-6, Budapest, 1097, Hungary

    Mónika Rózsa

Authors
  1. Péter Gyarmati
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  2. Giorgi Metreveli
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  3. Sándor Kecskeméti
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  4. Mónika Rózsa
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  5. Sándor Belák
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  6. István Kiss
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Correspondence to Péter Gyarmati.

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Gyarmati, P., Metreveli, G., Kecskeméti, S. et al. Molecular analysis and characterization of swine and human influenza viruses isolated in Hungary in 2006–2007. Virus Genes 39, 186–192 (2009). https://doi.org/10.1007/s11262-009-0387-5

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  • DOI: https://doi.org/10.1007/s11262-009-0387-5

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