Skip to main content
SpringerLink
Log in

Translation of Varicella-Zoster Virus Genes During Human Ganglionic Latency

  • Published:
Virus Genes Aims and scope Submit manuscript

Abstract

Immunohistochemical analysis of fixed tissue sections of human trigeminal ganglia (TG) and dorsal root ganglia (DRG) revealed the neuronal expression of proteins encoded by Varicella-zoster virus (VZV) genes 21, 29, 62 and 63. These proteins were detected mainly in the neuronal cytoplasm, are likely to be present in low abundance during VZV latency, and mirror the profile of VZV gene transcription.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Gilden D.H. Kleinschmidt-DeMasters B.K. LaGuardia J. J., and Cohrs R.J., N Engl J Med 342, 635–645, 2000.

    PubMed  Google Scholar 

  2. Kennedy P.G. E., Rev Med Virol 12, 327–334, 2002.

    PubMed  Google Scholar 

  3. Cohrs R.J., Barbour M.B., and Gilden D.H., J Virol 70, 2789–2796, 1996.

    PubMed  Google Scholar 

  4. Kennedy P.G. E., Grinfeld E, and Bell J.E., J Virol 74, 11893–11898, 2000.

    PubMed  Google Scholar 

  5. Croen K.D., Ostrove J.M., Dragovic L.J., and Straus S.E., Proc Natl Acad Sci USA 85, 9773–9777, 1988.

    PubMed  Google Scholar 

  6. Mahalingam R., Wellish M., Cohrs R., Debrus S., Piette J., Rentier B., and Gilden D.H., Proc Natl Acad Sci USA 93, 2122–2124, 1996.

    PubMed  Google Scholar 

  7. Kennedy P.G. E., Grinfeld E., Bontems S., and Sadzot-Delvaux C., Virology 289, 218–223, 2001.

    PubMed  Google Scholar 

  8. Cohrs R.J., Gilden D.H., Kinchington P.R., Grinfeld E., and Kennedy P.G. E., J Virol 77, 6660–6665, 2003.

    PubMed  Google Scholar 

  9. Lungu O., Panagiotidis C.A., Annunziato P.W., Gershon A. A., and Silverstein S.J., Proc Natl Acad Sci USA 95, 7080–7085, 1998.

    PubMed  Google Scholar 

  10. Mahalingam R., Lasher R., Wellish M., Cohrs R.J., and Gilden D.H., J Virol 72, 6832–6837, 1998.

    PubMed  Google Scholar 

  11. Sabella C., Lowry P.W., Abbruzzi G.M., Koropchak C.M., Kinchington P.R., Sadegh-Zadeh M., Hay J., Ruyechan W. T., and Arvin A.M., J Virol 67, 7673–7676, 1993.

    PubMed  Google Scholar 

  12. Cohrs R.J., Randall J., Smith J., Gilden D.H., Dabrowski C., van Der Keyl H., and Tal-Singer R., J Virol 74, 11464–11471, 2000.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Scotland, UK

    Esther Grinfeld & Peter Kennedy

Authors
  1. Esther Grinfeld
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Peter Kennedy
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Grinfeld, E., Kennedy, P. Translation of Varicella-Zoster Virus Genes During Human Ganglionic Latency. Virus Genes 29, 317–319 (2004). https://doi.org/10.1007/s11262-004-7434-z

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11262-004-7434-z

Search

Navigation