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Retrospective study of single-use digital flexible ureteroscopic lithotripsy versus miniaturized percutaneous nephrolithotomy for 1.5–2.5cm lower pole renal stones

  • Urology - Original Paper
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Abstract

Purpose

Retrospective analysis was performed on the clinical information of patients with 1.5–2.5 cm lower pole renal stones treated by single-use digital flexible ureteroscopic lithotripsy (fURS) and miniaturized percutaneous nephrolithotomy (MPCNL) in affiliated hospital of the Nantong University from January 2020 to December 2022. To compare the safety and efficacy of single-use fURS and MPCNL in the treatment from 1.5cm to 2.5cm lower pole renal stones.

Methods

Clinical information of 141 patients were collected and divided into single-use fURS group and MPCNL group according to their treatment methods, including 83 patients in the single-use fURS group and 58 patients in the MPCNL group. Baseline data, data on the clinical characteristics of stones, laboratory examination data, operation time, and postoperative data of the two groups were collected. Statistical analysis was made on the collected data to analyze the differences and causes between the two groups of patients.

Results

There was no significant difference in the baseline data and preoperative clinical features of 141 patients between the two groups (P > 0.05). In comparison of postoperative serum indexes, the drop values of hemoglobin and creatinine in single-use fURS group were lower than those in MPCNL group, and the difference was statistically significant (P < 0.05). The stone free rate was higher in the MPCNL group than in the single-use fURS group on the first day after surgery. At the 1st month after surgery, the two groups were similar. At 3rd month after surgery, the single-use fURS group was slightly higher than the MPCNL group, with no statistical significance (P > 0.05). The total complication rate in single-use fURS group was slightly lower than that in MPCNL group, but there was no statistical significance (P > 0.05).

Conclusions

Single-use fURS has similar safety and efficacy to MPCNL in the treatment of 1.5–2.5cm lower pole renal stones. Single-use fURS may be a new option for the treatment of these stones.

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Data will be provided upon request.

Abbreviations

Single-use fURS:

Single-use digital flexible ureteroscopic lithotripsy

MPCNL:

Miniaturized percutaneous nephrolithotomy

IPA:

Infundibular pelvic angle

SFR:

Stone-free rate

ESWL:

Extracorporeal shock wave lithotripsy

PCNL:

Percutaneous nephrolithotomy

FURL:

Flexible ureteroscopic lithotripsy

UMP:

Ultra-mini percutaneous nephrolithotomy

SMP:

Channel and super-mini percutaneous nephrolithotomy

BMI:

Body mass index

CT:

Computed tomography

RIRS:

Retroactive intrarenal surgery

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Funding

This article was funded by the National Natural Science Foundation of China [grant number: 81771571] and Postgraduate Research & Practice Innovation Program of Jiangsu Province ( SJCX23_1792), The funder had no role in study design, analysis, interpretation of data, the writing of the manuscript and the decision to submit the article for publication.

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Correspondence to Limin Ma or Yangbo Guan.

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The authors declare that there is no conflict of interest for the publication of this study.

Ethical approval

The whole study was approved by the Ethics Committee of Affiliated Hospital of Nantong University and the informed consent of enrolled patients was obtained. Besides, the study is also in line with the Helsinki Declaration.

Consent to participant

The whole study was approved by the Ethics Committee of Affiliated Hospital of Nantong University and the informed consent of enrolled patients was obtained. Besides, the study is also in line with the Helsinki Declaration.

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Meng, W., Zhang, H., Wang, J. et al. Retrospective study of single-use digital flexible ureteroscopic lithotripsy versus miniaturized percutaneous nephrolithotomy for 1.5–2.5cm lower pole renal stones. Int Urol Nephrol 56, 55–62 (2024). https://doi.org/10.1007/s11255-023-03771-2

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