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Heat shock protein 70, oxidative stress, and antioxidant status in periparturient crossbred cows supplemented with α-tocopherol acetate

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A Publisher’s Erratum to this article was published on 22 February 2014

Abstract

The study was conducted to investigating the effect of α-tocopherol acetate on heat shock protein 70 (Hsp70), oxidative stress, and antioxidant status during periparturient period in medium body condition score crossbred cows. Twenty crossbred Karan Fries cows with confirmed pregnancy were selected 2 months before expected date of calving. The cows were randomly distributed in to two groups: 10 cows were kept as control and 10 were supplemented with α-tocopherol acetate during dry period for 2 months. Blood samples were collected at −20, −10, −5, 0, 5, 10, and 20 days in relation to the expected date of calving. Superoxide dismutase, catalase, and total immunoglobulin were significantly higher (P < 0.01) in treatment as compared to control cows. Heat shock protein 70 and thiobarbituric acid reactive substance levels were significantly lower (P < 0.01) in the treatment cows than their counterpart. Treatment with α-tocopherol acetate during dry period resulted in reduced oxidative stress, heat shock protein Hsp70 levels, improved antioxidant, and improved immunity status indicating beneficial effect of α-tocopherol acetate treatment.

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Abbreviations

SOD:

Superoxide dismutase

CAT:

Catalase

TBARS:

Thiobarbituric acid reactive substance

Hsp70:

Heat shock protein 70

ROS:

Reactive oxygen species

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Authors and Affiliations

  1. Dairy Cattle Physiology Division, National Dairy Research Institute (NDRI), Karnal, 132001, Haryana, India

    Anjali Aggarwal,  Ashutosh, Gulab Chandra & Anil Kumar Singh

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  1. Anjali Aggarwal
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  2. Ashutosh
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  3. Gulab Chandra
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  4. Anil Kumar Singh
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Corresponding author

Correspondence to Gulab Chandra.

Additional information

An erratum to this article is available at http://dx.doi.org/10.1007/s11250-014-0555-z.

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Aggarwal, A., Ashutosh, Chandra, G. et al. Heat shock protein 70, oxidative stress, and antioxidant status in periparturient crossbred cows supplemented with α-tocopherol acetate. Trop Anim Health Prod 45, 239–245 (2012). https://doi.org/10.1007/s11250-012-0196-z

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