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Two-Step Preparation of Benzylacetone

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Abstract

Two-step preparation of benzylacetone has been investigated using layered double hydroxides (LDHs) as catalysts for aldol condensation of benzaldehyde and acetone and Ni supported catalysts for consecutive hydrogenation of benzylideneacetone. Activity and selectivity of LDHs of various Mg/Al ratios to desired product, benzylideneacetone, have been compared in the liquid phase at 333 K. An aldol condensation yield at 100 % conversion of benzaldehyde was 78 % using catalyst HT-2.0. In the following, optimal hydrogenation conditions—temperature of 353 K, hydrogen pressure of 5 MPa and 5 wt% of catalyst NiSAT® 320 were found. At 95 % conversion of benzylideneacetone the selectivity to desired product was 99 %.

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Acknowledgments

The financial support from the Ministry of Education, Youth and Sports of the Czech Republic by the research project # MSM 604 613 73 01 is gratefully acknowledged. LDHs catalysts were prepared, in kindly cooperation with Department of Solid State Engineering, ICT Prague. Süd-Chemie AG is gratefully acknowledged for providing the catalysts.

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Authors and Affiliations

  1. Department of Organic Technology, Institute of Chemical Technology Prague, Technicka 5, 166 28, Prague 6, Czech Republic

    Iva Paterová, Eliška Vyskočilová & Libor Červený

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  1. Iva Paterová
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  2. Eliška Vyskočilová
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  3. Libor Červený
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Correspondence to Iva Paterová.

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Paterová, I., Vyskočilová, E. & Červený, L. Two-Step Preparation of Benzylacetone. Top Catal 55, 873–879 (2012). https://doi.org/10.1007/s11244-012-9853-8

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  • DOI: https://doi.org/10.1007/s11244-012-9853-8

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