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Catalytic thiomethylation of regioisomeric aminobenzamides using bis(N,N-dimethylamino)methane and α,ω-alkanedithiols

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Abstract

A chemoselective synthesis of acyclic and cyclic S-containing aminobenzamides was developed. The method involved samarium-catalyzed thiomethylation of regioisomeric aminobenzamides at the amino group using either bis(N,N-dimethylamino)methane and α,ω-alkanedithiols or bis-1,3-aminosulfides.

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Authors and Affiliations

  1. Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, 141 prosp. Oktyabrya, Bashkortostan, 450075, Ufa, Russian Federation

    R. R. Khairullina, T. V. Tyumkina & A. G. Ibragimov

Authors
  1. R. R. Khairullina
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  2. T. V. Tyumkina
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  3. A. G. Ibragimov
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Corresponding author

Correspondence to R. R. Khairullina.

Additional information

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 4, pp. 757–762, April, 2021.

This work was financially supported by the Ministry of Science and Higher Education of the Russian Federation (Federal Target Program No. 2019-05-595-000-058) and was carried out using the equipment of the Regional center for collective use of unique equipment “Agidel” at the Institute of Petrochemistry and Catalysis of the Ufa Federal Research Center of the Russian Academy of Sciences in accordance with the research plans of IPC UFRC RAS (Project No. AAAA-A19-119022290010-9 (2019–2021)).

This paper does not contain descriptions of studies on animals and humans.

The authors declare no competing interests.

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Khairullina, R.R., Tyumkina, T.V. & Ibragimov, A.G. Catalytic thiomethylation of regioisomeric aminobenzamides using bis(N,N-dimethylamino)methane and α,ω-alkanedithiols. Russ Chem Bull 70, 757–762 (2021). https://doi.org/10.1007/s11172-021-3147-x

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  • DOI: https://doi.org/10.1007/s11172-021-3147-x

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