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Catalytic Cycloaminomethylation of Aminobenzamides with 1,3-Bis[dimethylamino(methoxy)methyl]thiourea

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Abstract

Efficient methods of the synthesis of cyclophanes containing the thiourea moiety via the reaction of o-, m-, and p-aminobenzamides with 1,3-bis(dimethylaminomethyl)thiourea or 1,3-bis(methoxymethyl)thiourea using NiCl2·6H2O and SmCl3·6H2O as catalysts have been developed.

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Authors and Affiliations

  1. Institute of Petrochemistry and Catalysis of the Russian Academy of Sciences, pr. Oktyabrya 141, Ufa, 450075, Russia

    R. R. Khairullina, T. V. Tyumkina, A. R. Geniyatova & A. G. Ibragimov

  2. Ufa Institute of Chemistry of the Russian Academy of Sciences, pr. Oktyabrya 71, Ufa, 450054, Russia

    M. F. Abdullin

Authors
  1. R. R. Khairullina
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  2. T. V. Tyumkina
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  3. A. R. Geniyatova
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  4. M. F. Abdullin
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  5. A. G. Ibragimov
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Correspondence to R. R. Khairullina.

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Khairullina, R.R., Tyumkina, T.V., Geniyatova, A.R. et al. Catalytic Cycloaminomethylation of Aminobenzamides with 1,3-Bis[dimethylamino(methoxy)methyl]thiourea. Russ J Gen Chem 89, 378–384 (2019). https://doi.org/10.1134/S1070363219030022

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  • DOI: https://doi.org/10.1134/S1070363219030022

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