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Di-n-butyl ammonium chlorosulfonate ionic liquids as an efficient and recyclable catalyst for the synthesis of 1,4-dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-3-carboxylates under solvent-free ultrasound irradiation

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Abstract

In this study, we present a straightforward, efficient and convenient approach for the synthesis of medicinally important 1,4-dihydrobenzo[4,5] imidazo [1,2-a]pyrimidine-3-carboxylates via three-component reactions of aldehydes, 1H-benzo[d]imidazol-2-amine and active methylene compounds in the presence of di-n-butyl ammonium chlorosulfonate ionic liquids (DBA IL) under ultrasound irradiation. This process develops the synthetic potential of ultrasound irradiation with DBA IL combination and presents much compensation, such as outstanding product yields, reusable catalyst, less reaction periods, gainful cost, easy work-up/purification and environmentally benign reaction conditions.

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The attractive features of this methodology are simple procedure, green reaction, reusability and high efficiency of the catalyst, and easy workability.

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Authors and Affiliations

  1. Department of Image Science and Engineering, Pukyong National University, Busan, 608-737, Republic of Korea

    Mudumala Veeranarayana Reddy, Avuthu Vidya Sagar Reddy & Yeon Tae Jeong

Authors
  1. Mudumala Veeranarayana Reddy
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  2. Avuthu Vidya Sagar Reddy
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  3. Yeon Tae Jeong
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Correspondence to Yeon Tae Jeong.

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Reddy, M.V., Reddy, A.V.S. & Jeong, Y.T. Di-n-butyl ammonium chlorosulfonate ionic liquids as an efficient and recyclable catalyst for the synthesis of 1,4-dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-3-carboxylates under solvent-free ultrasound irradiation. Res Chem Intermed 42, 4893–4906 (2016). https://doi.org/10.1007/s11164-015-2328-3

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