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Nutrition and neuroendocrine tumors: An update of the literature

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Abstract

Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasms with worldwide increasing incidence, high prevalence and survival. Both the tumor itself and the systemic therapy may have an impact on patients’ nutrition. Malnutrition negatively impacts on outcome in NETs patients. Moreover, it has been demonstrated that body mass index was a risk factor for NET development and that metabolic syndrome was associated with worse prognosis in these patients. Of note, food could also interact with the metabolism of oral target therapy and antineoplastic agents used for the treatment of progressive NETs. Therefore, the nutritional assessment, based on body composition, and lifestyle modifications should be an integral component of management of the NET patients. The nutrition care plans are an integral part of the multidisciplinary management team for patients with NETs. Nutritionists with expertise in NETs can provide dietary approaches to improve the quality of life and nutritional status during various therapeutic modalities used in patients with NETs. The aim of this review is to critically discuss the importance of nutrition and body composition in patients with NETs.

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Author notes

  1. Barbara Altieri and Luigi Barrea contributed equally to this work.

Authors and Affiliations

  1. Department of Clinical Medicine and Surgery, Federico II University, Via Sergio Pansini 5, 82121, Naples, Italy

    Barbara Altieri, Luigi Barrea, Roberta Modica, Giovanna Muscogiuri, Silvia Savastano, Annamaria Colao & Antongiulio Faggiano

  2. Division of Endocrinology and Diabetes, Department of Internal Medicine I, University Hospital, University of Wuerzburg, Wuerzburg, Germany

    Barbara Altieri

Authors
  1. Barbara Altieri
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  2. Luigi Barrea
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  3. Roberta Modica
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  4. Giovanna Muscogiuri
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  5. Silvia Savastano
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  6. Annamaria Colao
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  7. Antongiulio Faggiano
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Correspondence to Antongiulio Faggiano.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Altieri, B., Barrea, L., Modica, R. et al. Nutrition and neuroendocrine tumors: An update of the literature. Rev Endocr Metab Disord 19, 159–167 (2018). https://doi.org/10.1007/s11154-018-9466-z

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  • DOI: https://doi.org/10.1007/s11154-018-9466-z

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