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Using a Molecular Sensor Array with Colorimetric Detection to Identify Active Ingredients in Drug Formulations

  • STRUCTURE OF CHEMICAL COMPOUNDS, METHODS OF ANALYSIS AND PROCESS CONTROL
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Pharmaceutical Chemistry Journal Aims and scope

A method for multiplex digital colorimetric qualitative analysis of nonsteroidal anti-inflammatory drugs (meloxicam, acetylsalicylic acid and its metabolites, paracetamol), β-adrenoblockers (carvedilol), secretolytics (bromhexine), fluoroquinolones (ofloxacin), metabolic stimulants (meldonium dihydrate), etc., was developed. The molecular chip operating efficiency was confirmed by verifying the authenticity of >40 medicinal substances. The proposed universal approach was new in principle and could be used for pharmaceutical quality control.

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Authors and Affiliations

  1. Department of Chemistry, M. V. Lomonosov Moscow State University, 1/3 Leninskie Gory, Moscow, 119991, Russia

    A. A. Chaplenko, O. V. Monogarova & K. V. Oskolok

Authors
  1. A. A. Chaplenko
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  2. O. V. Monogarova
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  3. K. V. Oskolok
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Corresponding author

Correspondence to A. A. Chaplenko.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 53, No. 4, pp. 44 – 49, April, 2019.

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Chaplenko, A.A., Monogarova, O.V. & Oskolok, K.V. Using a Molecular Sensor Array with Colorimetric Detection to Identify Active Ingredients in Drug Formulations. Pharm Chem J 53, 347–352 (2019). https://doi.org/10.1007/s11094-019-02004-0

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  • DOI: https://doi.org/10.1007/s11094-019-02004-0

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