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Aptamer-Based Sensors for Drug Analysis

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Nanosensing and Bioanalytical Technologies in Food Quality Control

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Abstract

The uncontrolled use of drugs endangers human health and causes drastic economic losses and irreparable consequences. Today, there is a great demand to introduce accurate, potent, real-time, and rapid methodologies for sensitive detection and quantification of drugs. To overcome this challenging difficulty, biosensors have been introduced as valuable tools. Among the diverse kinds of biosensors, aptamer-based biosensors (aptasensors) have evolved as novel candidates for the sensitive evaluation of different groups of drugs, owing to their superior specificity, sensitivity, and selectivity. This chapter encompasses the recent progress in the development of aptasensors to quantitatively monitor various types of drugs. Besides, sensing mechanisms associated with the aptasensors are given that provide ideas to develop the novel aptasensing platforms as the portable test kits for the on-site detection of drugs.

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Authors and Affiliations

  1. Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

    Zahra Khoshbin & Khalil Abnous

  2. Department of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

    Zahra Khoshbin & Khalil Abnous

  3. Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

    Elham Sameiyan

  4. Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

    Seyed Mohammad Taghdisi

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  1. Zahra Khoshbin
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  2. Elham Sameiyan
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  3. Khalil Abnous
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  4. Seyed Mohammad Taghdisi
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Correspondence to Khalil Abnous .

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Editors and Affiliations

  1. Laboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, Uttar Pradesh, India

    Pranjal Chandra

  2. Food Biotechnology Research Laboratory, Department of Food Engineering and Technology, Sant Longowal Institute of Engineering and Technology, Longowal, Punjab, India

    Parmjit S. Panesar

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Khoshbin, Z., Sameiyan, E., Abnous, K., Taghdisi, S.M. (2022). Aptamer-Based Sensors for Drug Analysis. In: Chandra, P., Panesar, P.S. (eds) Nanosensing and Bioanalytical Technologies in Food Quality Control. Springer, Singapore. https://doi.org/10.1007/978-981-16-7029-9_3

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