Using extracellular recording of spike activity from single neurons of field 21a of the cat neocortex, we examined in detail the spatial organization of receptive fields (RFs) of such cells after conditions of presentation of an immobile blinking light spot (a static RF) and moving visual stimuli (dynamic RFs). As was shown, the excitability of different RF subfields of a group of neurons possessing homogeneous on–off organization of the static RF changes significantly depended on the contrast, shape, dimension, orientation, and direction of movement of the applied mobile visual stimulus. This is manifested in changes in the number of discharge centers and shifts of their spatial localization. A hypothesis on the possible role of synchronous activation of the neurons neighboring the cell under study in the formation of an additional neuronal mechanism providing specialization of neuronal responses is proposed.
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K. Mizobe, M. Itoi, T. Kaihara, and K. Toyama, “Neuronal responsiveness in area 21a of the cat,” Brain Res., 438, No. 3, 307–310 (1988).
J. W. Morley and R. M. Vickery, “Spatial and temporal frequency selectivity of cells in area 21a of the cat,” J. Physiol., 501, No. 2, 405–413 (1997).
J. W. Morley and R. M. Vickery, “Binocular interactions in area 21a of the cat,” NeuroReport, 10, No. 11, 2241–2244 (1999).
B. A. Harutiunian-Kozak, D. K. Khachvankian, J. A. Kozak, et al., “Dynamic spatial organization of receptive fields of neurons in the 21a cortical area,” Neurophysiology, 42, No. 3, 175–184 (2010).
B. A. Harutiunian-Kozak, G. G. Grigorian, J. A. Kozak, et al., “Orientation sensitive properties of visually driven neurons in extrastriate area 21a of cat cortex,” Arch. Ital. Biol., 146, No. 2, 119–130 (2008).
P. O. Bishop, W. Kozak, and G. J. Vakkur, “Some quantitative aspects of cat’s eye: axis and plane reference, visual field coordinates and optics,” J. Physiol., 163, No. 3, 466–502 (1962).
R. Fernald and R. Chase, “An improved method for plotting retinal landmarks and focusing the eye,” Vis. Res., 11, No. 1, 95–96 (1971).
D. H. Hubel and T. N. Wiesel, “Receptive fields of single neurons in the cat’s striate cortex”, J. Physiol., 148, No. 3, 574–591 (1959).
D. H. Hubel and T. N. Wiesel, “Receptive fields, binocular interaction and functional architecture in cat’s visual corte,” J. Physiol., 160, No. 1, 106–154 (1962).
P. O. Bishop, J. S. Coombs, and G. H. Henry, “Responses to visual contours: spatiotemporal aspects of excitation in the receptive field of simple striate neurons,” J. Physiol., 219, No. 2, 625–657 (1971).
P. O. Bishop, J. S. Coombs, and G. H. Henry, “Receptive fields of simple cells in the cat striate cortex,” J. Physiol., 231, No. 1, 31–60 (1973).
R. C. Emerson and G. L Gerstein, “Simple striate neurons in cat. I Comparison of responses to moving and stationary stimuli,” J. Neurophysiol., 40, No. 1, 119–135 (1977).
D. Ferster and C. Koch, “Neuronal connections underlying orientation selectivity in cat visual cortex,” Trends Neurosci., 10, No. 12, 487–492 (1987).
J. Lampi, J. S. Anderson, D. C. Gillespi, and D. Ferster, “Prediction of orientation selectivity from receptive field architecture of simple cells of cat visual cortex,” Neuron, 30, No. 1, 267–274 (2001).
B. A. Harutiunian-Kozak, A. B. Sharanbekian, A. L. Kazarian, et al., “Spatial summation processes in the receptive fields of visually driven neurons of the cat’s cortical area 21a,” Arch. Ital. Biol., 144, No. 1, 127–144 (2006).
G. C. De Angelis, J. Ohzawa, and R. D. Freeman, “Receptive-field dynamics in the central visual pathway,” Trends. Neurosci., 18, No. 10, 451–468 (1995).
G. C. De Angelis, J. Ohzawa, and R. D. Freeman, “Spatiotemporal organization of simpLE cell receptive fields in the cat’s striate cortex,” J. Neurophysiol., 69, No. 4, 1091–1117 (1993).
J. A Hirsh and C. D. Gilbert, “Long term changes in synaptic strength along specific intrinsic pathways in the cat visual cortex,” J. Physiol., 461, No. 1, 247–262 (1993).
C. D. Gilbert and T. N. Wiesel, “Receptive field dynamics in adult primary visual cortex,” Nature, 356, No. 6365, 150–152 (1992).
N. M. Weinberger, “Dynamic regulation of receptive fields and maps in the adult sensory cortex,” Annu. Rev. Neurosci., 18, 129–158 (1995).
U. T. Eysel, D. Eyding, and G. Schweigart, “Repetitive optical stimulation elicits fast receptive field changes in mature visual cortex,” NeuroReport, 9, No. 5, 949–954 (1998).
K. Suder, K. Funke, Y. Zhao, et al., “Spatial dynamics of receptive fields in cat primary visual cortex related to the temporal structure of thalamocortical feedforward activity,” Exp. Brain Res., 144, No. 4, 430–444 (2002).
D. K. Khachvankian, J. A. Kozak, A. L. Ghazarian, et al., “Dynamics of neuronal receptive fields in extrastriate area 21a of the cat cortex,” Inform. Technol. Manag., No. 1, 191–202 (2011).
T. Galli, L. Chalupa, L. Maffei, and S. Bisti, “The organization of receptive fields in area 18 neurons of the cat varies with the spatio-temporal characteristics of the visual stimulus,” Exp. Brain Res., 71, No. 1, 1–7 (1988).
C. Kayser and P. Konig, “Feature selectivity in area 21a of the cat,” NeuroReport, 17, No. 8, 809–812 (2006).
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Khachvankyan, D.K., Kozak, Y.A., Kazaryan, A.L. et al. Reorganization of Receptive Fields of Cortical Field 21a Neurons and Formation of Responses to Moving Visual Stimuli. Neurophysiology 44, 33–41 (2012). https://doi.org/10.1007/s11062-012-9264-2
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DOI: https://doi.org/10.1007/s11062-012-9264-2