Skip to main content

Advertisement

Log in

Intraventricular gliosarcoma: unusual location of an uncommon tumor

  • Case Report
  • Published:
Journal of Neuro-Oncology Aims and scope Submit manuscript

Abstract

Gliosarcomas are uncommon variants of glioblastoma bearing the histological hallmark of two distinct tumor components (high grade glial and sarcomatous). They share similarities with glioblastomas as far as clinico-epidemiological and prognostic factors are concerned. They are commonly cortically-surfacing lesions occurring mostly in the supratentorial compartment. Intraventricular location of a gliosarcoma is very uncommon and reported only once before. We report one such case where the lesion was subependymal and protruded into the ventricle giving the appearance of a truly intraventricluar tumor. We discuss this case and review the relevant literature.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

References

  1. Stroebe H (1895) Uber entstehung und bau der gehirngliome. Beitr Pathol Anat Allg Pathol 18:405–486

    Google Scholar 

  2. Kleihues P, Burger PC, Scheithauer BW (1993) The new WHO classification of brain tumors. Brain Pathol 3:255–268

    Article  CAS  PubMed  Google Scholar 

  3. Pakos EE, Goussia AC, Zina VP, Pitouli EJ, Tsekeris PG (2005) Multi-focal gliosarcoma: a case report and review of the literature. J Neurooncol 74(3):301–304

    Article  CAS  PubMed  Google Scholar 

  4. Morantz RA, Feigin I, Ransohoff JIII (1976) Clinical and pathological study of 24 cases of gliosarcoma. J Neurosurg 45:398–408

    Article  CAS  PubMed  Google Scholar 

  5. Higashino T, Inamura T, Kawashima M, Ikezaki K, Miyazono M, Yoshiura T et al (2001) A lateral ventricular gliosarcoma arising in an ependymoma. Clin Neuropathol 20:219–223

    CAS  PubMed  Google Scholar 

  6. Behling E, Birbe R, Veznadaroglu E, Andrews DW, Flanders A, Kenyon LC (2004) Gliosarcoma arising from an anaplastic ependymoma: a case report of a rare entity. Hum Pathol 35(4):512–516

    Article  PubMed  Google Scholar 

  7. Feigin I, Ransohoff J, Lieberman A (1976) Sarcoma arising in oligodendroglioma of the brain. J Neuropathol Exp Neurol 35:679–684

    Article  CAS  PubMed  Google Scholar 

  8. Galanis E, Buckner JC, Dinapoli RP, Scheithauer BW, Jenkins RB, Wang CH et al (1998) Clinical outcome of gliosarcoma compared with glioblastoma multiforme: north central cancer treatment group results. J Neurosurg 89:425–430

    Article  CAS  PubMed  Google Scholar 

  9. Beaumont TL, Kupsky WJ, Barger GR, Sloan AE (2007) Gliosarcoma with multiple extracranial metastases: case report and review of the literature. J Neurooncol 83:39–46

    Article  PubMed  Google Scholar 

  10. Demirci S, Akalin T, Islekel S, Ertan Y, Anacak Y (2008) Multiple spinal metastases of cranial gliosarcoma: a case report and review of the literature. J Neurooncol 88(2):199–204

    Article  PubMed  Google Scholar 

  11. Waldron JS, Tihan T (2003) Epidemiology and pathology of intraventricular tumors. Neurosurg Clin N Am 14(4):469–482

    Article  PubMed  Google Scholar 

  12. Hercules SA, Ramesh VG, Paramasivan S, Kodiarasan P, Kumar MS (2007) Holoventricular glioma in a child case report. J Neurosurg 106(2 Suppl):134–135

    PubMed  Google Scholar 

  13. Maiuri F, Stella L, Benvenuti D, Giamundo A, Pettinato G (1990) Cerebral gliosarcomas: correlation of computed tomographic findings, surgical aspect, pathologic features, and prognosis. Neurosurgery 26:261–267

    Article  CAS  PubMed  Google Scholar 

  14. Meis JM, Martz KL, Nelson JS (1991) Mixed glioblastoma multiforme and sarcoma. A clinicopathologic study of 26 radiation therapy oncology group cases. Cancer 7:2342–2349

    Article  Google Scholar 

  15. Fischer S, Lee W, Aulisi E, Singh H (2007) Gliosarcoma with intramedullary spinal metastases: a case report and review of the literature. J Clin Oncol 25:447–449

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Aliasgar Moiyadi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Moiyadi, A., Sridhar, E. & Jalali, R. Intraventricular gliosarcoma: unusual location of an uncommon tumor. J Neurooncol 96, 291–294 (2010). https://doi.org/10.1007/s11060-009-9952-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11060-009-9952-y

Keywords

Navigation