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Fatty acid desaturases (FADs) modulate multiple lipid metabolism pathways to improve plant resistance

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Abstract

Background

Biological and abiotic stresses such as salt, extreme temperatures, and pests and diseases place major constraints on plant growth and crop yields. Fatty acids (FAs) and FA- derivatives are unique biologically active substance that show a wide range of functions in biological systems. They are not only participated in the regulation of energy storage substances and cell membrane plasm composition, but also extensively participate in the regulation of plant basic immunity, effector induced resistance and systemic resistance and other defense pathways, thereby improving plant resistance to adversity stress. Fatty acid desaturases (FADs) is involved in the desaturation of fatty acids, where desaturated fatty acids can be used as substrates for FA-derivatives.

Objective

In this paper, the role of omega-FADs (ω-3 FADs and ω-6 FADs) in the prokaryotic and eukaryotic pathways of fatty acid biosynthesis in plant defense against stress (biological and abiotic stress) and the latest research progress were summarized. Moreover’ the existing problems in related research and future research directions were also discussed.

Results

Fatty acid desaturases are involved in various responses of plants during biotic and abiotic stress. For example, it is involved in regulating the stability and fluidity of cell membranes, reactive oxygen species signaling pathways, etc. In this review, we have collected several experimental studies to represent the differential effects of fatty acid desaturases on biotic and abiotic species.

Conclusion

Fatty acid desaturases play an important role in regulating biotic and abiotic stresses.

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Data Availability

The data presented in this study are available on request from the corresponding author. The data are not publicly available due to privacy.

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Acknowledgements

This paper is supported by all authors. R.X., Y.Z., X.G, H.L and H.L. wrote the manuscript.

Funding

Innovative Research Group Project of the National Natural Science Foundation of China, 31971618, Hai Lu, The 111 Project, B13007, Hai Lu.

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  1. Ruixue Xiao, Yirong Zou and Xiaorui Guo have contributed equally to this work.

Authors and Affiliations

  1. National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, 100083, China

    Ruixue Xiao, Hui Li & Hai Lu

  2. Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, Beijing Forestry University, Beijing, 100083, China

    Ruixue Xiao, Hui Li & Hai Lu

  3. The Tree and Ornamental Plant Breeding and Biotechnology Laboratory of National Forestry and Grassland Administration, College of Biological Sciences and Biotechnology, Beijing Forestry University, Tsinghua East Road 35, Haidian District, Beijing, 100083, China

    Ruixue Xiao, Yirong Zou, Xiaorui Guo, Hui Li & Hai Lu

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Xiao, R., Zou, Y., Guo, X. et al. Fatty acid desaturases (FADs) modulate multiple lipid metabolism pathways to improve plant resistance. Mol Biol Rep 49, 9997–10011 (2022). https://doi.org/10.1007/s11033-022-07568-x

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