Abstract
To assess the capability of Kyoto University Research Reactor to supply the domestic needs of medical isotopes, its neutron flux has been fully characterized. The production rates of theranostics radionuclides 177Lu (from 176Lu (n, γ) 177Lu), 176Lu (n, γ) 177mLu/177Lu and 176Yb (n, γ) \(^{177} {\text{Yb}}\mathop{\longrightarrow}\limits{{\beta^{ - } (1.88\;{\text{hr}})}}^{177} {\text{Lu}}\) reactions), and 47Sc (from 46Ca (n, γ) \({^{47} {\text{Ca}}} \mathop{\longrightarrow}\limits^{{\beta^{ - } (4.54\;{\text{d}})}} {^{47} {\text{Sc}}}\) and Ti (n, p) 47Sc) were evaluated. The activity (per gram of target) of 47Sc produced from Ti was found to be 10 times higher than that produced from Ca. Production of 177Lu from the decay of its isomer 177mLu was found to be produce less radioactive wastes than Yb route and can be used as a generator for long-time use.
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Soliman, M.A., Mohamed, N.M.A., Takamiya, K. et al. Estimation of 47Sc and 177Lu production rates from their natural targets in Kyoto University Research Reactor. J Radioanal Nucl Chem 324, 1099–1107 (2020). https://doi.org/10.1007/s10967-020-07156-y
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DOI: https://doi.org/10.1007/s10967-020-07156-y