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Elemental analysis of brahmi (Bacopa monnieri) extracts by neutron activation and its bioassay for antioxidant, radio protective and anti-lipid peroxidation activity

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Abstract

Brahmi (Bacopa monnieri) leaves, known as nervine tonic in Ayurveda, and its aqueous (BA), methanolic (BM) and aqueous–methanolic (BAM) extracts were analyzed for 7 minor (Al, Fe, Na, K, Ca, P, Cl) and 18 trace (As, Au, Ba, Br, Co, Cr, Cu, Hf, Hg, La, Mn, Rb, Se, Sm, Sr, Th, V, Zn) elements by INAA. BAM extract showed maximum contents of Na, K, Cl and significant amounts of Mn, Co, Zn. It was also found as effective scavenger of DPPH radicals with 33.5% total phenolic content, highest γ-ray radioprotective effect and higher anti lipid peroxidation activity.

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Acknowledgement

Financial assistance from the Board of Research in Nuclear Sciences, DAE, Government of India, via Grant no 2000/37/5 is gratefully acknowledged.

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Authors and Affiliations

  1. Department of Chemistry, Indian Institute of Technology, Roorkee, 247667, India

    A. N. Garg & A. Kumar

  2. Radiochemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai, 400085, India

    A. G. C. Nair & A. V. R. Reddy

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  1. A. N. Garg
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  2. A. Kumar
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  3. A. G. C. Nair
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  4. A. V. R. Reddy
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Correspondence to A. N. Garg.

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Garg, A.N., Kumar, A., Nair, A.G.C. et al. Elemental analysis of brahmi (Bacopa monnieri) extracts by neutron activation and its bioassay for antioxidant, radio protective and anti-lipid peroxidation activity. J Radioanal Nucl Chem 281, 53–58 (2009). https://doi.org/10.1007/s10967-009-0081-z

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  • DOI: https://doi.org/10.1007/s10967-009-0081-z

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