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Antioxidant Potential and In Situ Analysis of Major and Trace Element Determination of Ood-saleeb, a Known Unani Herbal Medicine by ICP-MS

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Abstract

The intention of the present research work was to investigate the antioxidant activity and trace element analysis of Ood-saleeb, a known herbal medicine. Preliminary screening of phytochemicals showed that the extract of Ood-saleeb had flavonoids and phenolics. The significant activities in all antioxidant assays were observed in the extract of Ood-saleeb in comparison with the standard antioxidant with respect to dose of Ood-saleeb. Incredible activities to scavenge reactive oxygen species were also observed by the extract of Ood-saleeb. The IC50 values of all factors were determined using ascorbic acid as a standard. The inductive coupled plasma-mass spectroscopy (ICP-MS) was employed for the estimation of trace elements in Ood-saleeb extract. The concentrations of up to 18 elements were detected successfully. Silicon was found in high concentration (85.3 μg/g) while lithium was in low concentration (3 ng/g). The trace elements in the sample were found at different percentage levels which play a key role in the treatment of diseases.

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Acknowledgments

The author would like to extend their sincere appreciation to the Deanship of Scientific Research at King Saud University for its funding through research group number (RG# 1435-017).

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Authors and Affiliations

  1. Department of Pharmaceutics, College of Pharmacy, King Saud University, PO Box 2457, Riyadh, 11451, Saudi Arabia

    Mohammad Raish, Fahad I. Al-Jenoobi, Abdullah M. Al-Mohizea, Kazi Mohsin & Faiyaz Shakeel

  2. Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia

    Ajaz Ahmad & Khalid M. Alkharfy

  3. Research Centre, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia

    Syed Rizwan Ahamad

  4. Quality Assurance Unit, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia

    Naushad Ali

  5. Center of Excellence in Biotechnology Research (CEBR), King Saud University, Riyadh, 11451, Saudi Arabia

    Faiyaz Shakeel

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  1. Mohammad Raish
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  2. Ajaz Ahmad
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Correspondence to Faiyaz Shakeel.

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Raish, M., Ahmad, A., Alkharfy, K.M. et al. Antioxidant Potential and In Situ Analysis of Major and Trace Element Determination of Ood-saleeb, a Known Unani Herbal Medicine by ICP-MS. Biol Trace Elem Res 172, 521–527 (2016). https://doi.org/10.1007/s12011-015-0607-x

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