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Volumetric Properties of Amino Acids in Aqueous N-methylacetamide Solutions at 298.15 K

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Abstract

The apparent molar volumes (V φ ) of glycine, L-alanine and L-serine in aqueous 0 to 4 mol⋅kg−1 N-methylacetamide (NMA) solutions have been obtained by density measurement at 298.15 K. The standard partial molar volumes (\(V_{\phi}^{0})\) and standard partial molar volumes of transfer (\(\Delta_{\mathrm{tr}}V_{\phi}^{0})\) have been determined for these amino acids. It has been show that hydrophilic-hydrophilic interactions between the charged groups of the amino acids and the –CONH– group of NMA predominate for glycine and L-serine, but for L-alanine the interactions between its side group (–CH3) and NMA predominate. The –CH3 group of L-alanine has much more influence on the value of \(\Delta_{\mathrm{tr}}V_{\phi}^{0}\) than that of the –OH group of L-serine. The results have been interpreted in terms of a co-sphere overlap model.

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References

  1. Biswajit, S., Vikas, K.D., Mahendra, N.R.: Apparent molar volumes and viscosity B-coefficients of some amino acids in aqueous tetramethylammonium iodide solutions at 298.15 K. J. Chem. Eng. Data 52, 1768–1772 (2007)

    Article  Google Scholar 

  2. Yan, Z.N., Wang, J.J., Lu, J.S.: Viscosity behavior of some α-amino acids and their groups in water–sodium acetate mixtures. Biophys. Chem. 3, 199–207 (2002)

    Article  Google Scholar 

  3. Lark, B.S., Patyar, P., Banipal, T.S., Kishore, N.: Densities, partial molar volumes, and heat capacities of glycine, L-alanine, and L-leucine in aqueous magnesium chloride solutions at different temperatures. J. Chem. Eng. Data 49, 553–565 (2004)

    Article  CAS  Google Scholar 

  4. Banipal, T.S., Singh, G., Lark, B.S.: Partial molar volumes of transfer of some amino acids from water to aqueous glycerol solutions at 25 °C. J. Solution Chem. 30, 657–670 (2001)

    Article  CAS  Google Scholar 

  5. Banipal, T.S., Singh, G.: Densities and partial molar volumes of some amino acids and diglycine in aqueous n-propanol solutions at 25 °C. J. Solution Chem. 32, 997–1015 (2003)

    Article  CAS  Google Scholar 

  6. Xu, L., Ding, C.R., Lin, R.S.: Transfer volumes of glycine, L-alanine, and L-serine from water to 1,2-butanediol-water mixtures at 298.15 K. J. Solution Chem. 35, 191–200 (2006)

    Article  CAS  Google Scholar 

  7. Palecz, B.: Thermochemical properties of L-α-amino acids in electrolyte–water mixtures. Fluid Phase Equilib. 167, 253–261 (2000)

    Article  CAS  Google Scholar 

  8. Lu, Y., Bai, T.C., Xie, W., Lu, J.S.: The enthalpic interaction of α-alanine with alkali metal halides in water at 298.15 K. Thermochim. Acta 319, 11–15 (1998)

    Article  CAS  Google Scholar 

  9. Yu, L., Hu, X.G., Lin, R.S., Shao, S., Zhang, H.L.: Enthalpic interactions of glycine in aqueous sodium halide solutions. Thermochim. Acta 378, 1–8 (2001)

    Article  CAS  Google Scholar 

  10. Wang, X., Xu, L., Lin, R.S., Sun, D.Z.: Enthalpies of dilution of glycine, L-alanine and L-serine in aqueous potassium chloride solutions. Thermochim. Acta 425, 31–37 (2005)

    Article  CAS  Google Scholar 

  11. Davis, K.G., Lilley, T.H.: Aqueous solutions containing amino acids and peptides. Part 25. The enthalpy of interaction at 298.15 K of glycine with potassium halides. Thermochim. Acta 107, 267–276 (1986)

    Article  CAS  Google Scholar 

  12. Chalikian, T.V., Breslauer, K.J.: Thermodynamic analysis of biomolecules: a volumetric approach. Struct. Biol. 8, 657–664 (1998)

    CAS  Google Scholar 

  13. Bhat, R., Ahluwalia, J.C.: Partial molar heat capacities and volumes of transfer of some amino acids and peptides from water to aqueous sodium chloride solutions at 298.15 K. J. Phys. Chem. 89, 1099–1105 (1985)

    Article  CAS  Google Scholar 

  14. Badarayani, R., Kumar, A.: Ionic interactions from volumetric investigations of L-alanine in NaBr, KCl, KBr and MgCl2 up to high concentrations. Fluid Phase Equilib. 201, 321–333 (2002)

    Article  CAS  Google Scholar 

  15. Ali, A., Hyder, S., Sabir, S., Chand, D., Nain, A.K.: Volumetric, viscometric, and refractive index behaviour of α-amino acids and their groups contribution in aqueous d-glucose solution at different temperatures. J. Chem. Thermodyn. 38, 136–143 (2006)

    Article  CAS  Google Scholar 

  16. Liu, C.L., Ma, L., Lin, R.: Enthalpies of transfer of amino acids from water to aqueous solutions of N-methylformamide and N,N-dimethylformamide at T=298.15 K. Thermochim. Acta 468, 116–118 (2008)

    Article  Google Scholar 

  17. Zhou, L., Liu, C.L.: Enthalpies of transfer of amino acids from water to aqueous solutions of N-methylacetamide and N,N-dimethylacetamide at T=298.15 K. Thermochim. Acta 482, 72–74 (2009)

    Article  CAS  Google Scholar 

  18. Liu, C.L., Zhou, L., Lin, R.S.: Interactions of some amino acids with aqueous N,N-dimethylacetamide solutions at 298.15 and 308.15 K: a volumetric approach. J. Solution Chem. 36, 923–937 (2007)

    Article  CAS  Google Scholar 

  19. Lin, G.M., Bian, P.F., Lin, R.S.: The limiting partial molar volume and transfer partial molar volume of glycylglycine in aqueous sodium halide solutions at 298.15 K and 308.15 K. J. Chem. Thermodyn. 38, 144–151 (2006)

    Article  CAS  Google Scholar 

  20. Shahidi, F., Harreil, P.G., Edward, J.T.: Partial molar volumes of organic compounds in water. III. Carbohydrates. J. Solution Chem. 5, 807–816 (1976)

    Article  CAS  Google Scholar 

  21. Desnoyers, J.E., Arel, M., Perron, G., Jolicoeur, C.: Apparent molar volumes of alkali halides in water at 25°. Influence of structural hydration interactions on the concentration dependence. J. Phys. Chem. 73, 3346–3351 (1969)

    Article  CAS  Google Scholar 

  22. Banerjee, T., Kishore, N.: Interactions of some amino acids with aqueous tetraethylammonium bromide at 298.15 K: A volumetric approach. J. Solution Chem. 34, 137–153 (2005)

    Article  CAS  Google Scholar 

  23. Chen, C.H., Berns, D.S.: Thermodynamic studies of protein–salt interaction: 1. Phycocyanin-tetrabutylammonium bromide and tetraethylammonium bromide. J. Phys. Chem. 81, 125–129 (1977)

    Article  CAS  Google Scholar 

  24. Chen, C.H., Berns, D.S.: Thermodynamic studies of protein-salt interactions. II. Effect of geometrical configuration in alkyl-substituted quaternary ammonium salts on their interactions with phycocyanin. J. Phys. Chem. 82, 2781–2786 (1978)

    Article  CAS  Google Scholar 

  25. Shahidi, F., Farrell, P.G.: Partial molar volumes of some α-aminocarboxylic acids in water. J. Chem. Soc. Faraday Trans. I 77, 963–968 (1981)

    Article  CAS  Google Scholar 

  26. Millero, F.J., Lo Surdo, A., Shin, C.: The apparent molar volumes and adiabatic compressibilities of aqueous amino acids at 25 °C. J. Phys. Chem. 82, 784–792 (1978)

    Article  CAS  Google Scholar 

  27. Berlin, E., Pallansch, M.J.: Densities of several proteins and L-amino acids in the dry state. J. Phys. Chem. 72, 1887–1889 (1968)

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Chemistry and Chemistry Engineering, Zao Zhuang University, Zao Zhuang, 277160, P.R. China

    Chunli Liu & Li Zhou

  2. Department of Chemistry, Zhejiang University, Hangzhou, 310027, P.R. China

    Ruisen Lin

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  1. Chunli Liu
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  2. Li Zhou
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  3. Ruisen Lin
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Correspondence to Chunli Liu.

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Liu, C., Zhou, L. & Lin, R. Volumetric Properties of Amino Acids in Aqueous N-methylacetamide Solutions at 298.15 K. J Solution Chem 39, 1253–1263 (2010). https://doi.org/10.1007/s10953-010-9585-y

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  • DOI: https://doi.org/10.1007/s10953-010-9585-y

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