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Rapid prototyping assisted fabrication of patient specific β-tricalciumphosphate scaffolds for bone tissue regeneration

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Abstract

Beta Tri calcium phosphate scaffolds were produced by inverse casting methodology using rapid prototyping technology. Β-TCP scaffold sintered at different temperatures were analyzed by using Scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, uniaxial compression test and cytotoxicity test. Results incorporate scaffold pore size, bonding, phase chance, porosity, mechanical strength, and cytotoxic profile with an increase in the sintering temperatures. Together, these properties are required for scaffold fabrication in the field of bone tissue regeneration.

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Authors and Affiliations

  1. Department of Mechanical Engineering, Visvesvaraya National Institute of Technology, Nagpur, India

    Pranav S. Sapkal & Abhaykumar M. Kuthe

  2. Biochemistry Research Laboratory, Central India Institute of Medical Sciences (CIIMS), Nagpur, India

    Rajpal S. Kashyap, Amit R. Nayak & Anuja P. Kawle

  3. Department of Metallurgical and Materials Engineering, Visvesvaraya National Institute of Technology, Nagpur, India

    Sudhanshu A. Kuthe

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  1. Pranav S. Sapkal
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  2. Abhaykumar M. Kuthe
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  3. Rajpal S. Kashyap
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  4. Amit R. Nayak
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  5. Sudhanshu A. Kuthe
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  6. Anuja P. Kawle
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Correspondence to Pranav S. Sapkal.

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Sapkal, P.S., Kuthe, A.M., Kashyap, R.S. et al. Rapid prototyping assisted fabrication of patient specific β-tricalciumphosphate scaffolds for bone tissue regeneration. J Porous Mater 23, 927–935 (2016). https://doi.org/10.1007/s10934-016-0150-y

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  • DOI: https://doi.org/10.1007/s10934-016-0150-y

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