Skip to main content

Advertisement

SpringerLink
Log in

SCIg vs IVIg: Let’s Give Patients the Choice!

  • Astute Clinician Report
  • Published:
Journal of Clinical Immunology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Ochs HD, Gupta S, Kiessling P, Nicolay U, Berger M, Subcutaneous Ig GSG. Safety and efficacy of self-administered subcutaneous immunoglobulin in patients with primary immunodeficiency diseases. J Clin Immunol. 2006;26(3):265–73.

    Article  CAS  PubMed  Google Scholar 

  2. Berger M. Choices in IgG replacement therapy for primary immune deficiency diseases: subcutaneous IgG vs. intravenous IgG and selecting an optimal dose. Curr Opin Allergy Clin Immunol. 2011;11(6):532–8.

    Article  CAS  PubMed  Google Scholar 

  3. Chapel HM, Spickett GP, Ericson D, Engl W, Eibls MM, Bjorkander J. The comparison of the efficacy and safety of intravenous versus subcutaneous immunoglobulin replacement therapy. J Clin Immunol. 2000;20(2):94–100.

    Article  CAS  PubMed  Google Scholar 

  4. Ballow M. Immunoglobulin therapy: methods of delivery. The J of allergy and clin immunol. 2008;122(5):1038–9.

    Article  Google Scholar 

  5. Haddad E, Barnes D, Kafal A. Home therapy with subcutaneous immunoglobulins for patients with primary immunodeficiency diseases. Transfusion and apheresis science : official j of the World Apher Assoc : official j of the Eur Soc for Haemapheresis. 2012;46(3):315–21.

    Google Scholar 

  6. Wasserman RL. Progress in gammaglobulin therapy for immunodeficiency: from subcutaneous to intravenous infusions and back again. J Clin Immunol. 2012;32(6):1153–64.

    Article  CAS  PubMed  Google Scholar 

  7. Eibl MM. History of immunoglobulin replacement. Immunol Allergy Clin N Am. 2008;28(4):737–64.

    Article  Google Scholar 

  8. Orbach H, Katz U, Sherer Y, Shoenfeld Y. Intravenous immunoglobulin: adverse effects and safe administration. Clin Rev Allergy Immunol. 2005;29(3):173–84.

    Article  CAS  PubMed  Google Scholar 

  9. Orange JS, Hossny EM, Weiler CR, Ballow M, Berger M, Bonilla FA, et al. Use of intravenous immunoglobulin in human disease: a review of evidence by members of the primary immunodeficiency committee of the american academy of allergy, asthma and immunology. The J of allergy and clin immunol. 2006;117(4 Suppl):S525–53.

    Article  CAS  Google Scholar 

  10. Kobrynski L. Subcutaneous immunoglobulin therapy: a new option for patients with primary immunodeficiency diseases. Biologics : targets & ther. 2012;6:277–87.

    CAS  Google Scholar 

  11. Gardulf A, Nicolay U, Math D, Asensio O, Bernatowska E, Bock A, et al. Children and adults with primary antibody deficiencies gain quality of life by subcutaneous IgG self-infusions at home. The J of allergy and clin immunol. 2004;114(4):936–42.

    Article  CAS  Google Scholar 

  12. Nicolay U, Kiessling P, Berger M, Gupta S, Yel L, Roifman CM, et al. Health-related quality of life and treatment satisfaction in North American patients with primary immunedeficiency diseases receiving subcutaneous IgG self-infusions at home. J Clin Immunol. 2006;26(1):65–72.

    Article  CAS  PubMed  Google Scholar 

  13. Fasth A, Nystrom J. Quality of life and health-care resource utilization among children with primary immunodeficiency receiving home treatment with subcutaneous human immunoglobulin. J Clin Immunol. 2008;28(4):370–8.

    Article  CAS  PubMed  Google Scholar 

  14. Ducruet T, Levasseur MC, Des Roches A, Kafal A, Dicaire R, Haddad E. Pharmacoeconomic advantages of subcutaneous versus intravenous immunoglobulin treatment in a Canadian pediatric center. The J of allergy and clin immunol. 2013;131(2):585–7. e1-3.

    Article  Google Scholar 

  15. Charles C, Gafni A, Whelan T. Decision-making in the physician ± patient encounter: revisiting the shared treatment decision-making model. Soc Sci Med. 1999;49(5):651–61.

    Article  CAS  PubMed  Google Scholar 

  16. Stevensona FA, Barry CA, Brittenb N, Barberc N, Bradley CP. Doctor-patient communication about drugs: the evidence for shared decision making. Soc Sci Med. 2000;50(6):829–40.

    Article  Google Scholar 

Download references

Acknowledgments

Elie Haddad is a scholar of Fonds de la Recherche en Santé au Québec (FRQS).

Funding

Funds to hire a native English speaker to help with editing the final version of the manuscript was provided by CSL Behring. The authors did not work for CSL Behring and CSL Behring was not involved in the design of the study or writing of the manuscript.

Author information

Authors and Affiliations

  1. Department of Pediatrics, University of Montreal, Centre Hospitalier Universitaire Sainte-Justine, 3175 Chemin de la Cote-Sainte-Catherine, Montreal, QC, H3T 1C5, Canada

    K. Samaan, M. C. Levasseur, H. Decaluwe, C. St-Cyr, A. Des Roches & E. Haddad

  2. Department of Allergy, University of Montreal, Centre Hospitalier Universitaire de Montreal, 3175 Chemin de la Cote-Sainte-Catherine, Montreal, QC, H3T 1C5, Canada

    H. Chapdelaine

  3. Department of Microbiology and Immunology, University of Montreal, Centre Hospitalier Universitaire Sainte-Justine, 3175 Chemin de la Cote-Sainte-Catherine, Montreal, QC, H3T 1C5, Canada

    E. Haddad

Authors
  1. K. Samaan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. C. Levasseur
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Decaluwe
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. C. St-Cyr
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. H. Chapdelaine
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A. Des Roches
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. E. Haddad
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to E. Haddad.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Samaan, K., Levasseur, M.C., Decaluwe, H. et al. SCIg vs IVIg: Let’s Give Patients the Choice!. J Clin Immunol 34, 611–614 (2014). https://doi.org/10.1007/s10875-014-0057-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10875-014-0057-9

Keywords

Search

Navigation