Abstract
Isosteviol derivative: benzoyloxymethyl (4α,8β,13β)-13-methyl-16-oxo-17-norkauran-18-carbonate ester was synthesized by esterification of isosteviol with chloromethyl benzoate and its crystal structure was determined by X-ray diffraction method. The compound crystallizes in the triclinic space group P1 with unit cell parameters: a = 8.784(3) Å, b = 9.079(3) Å, c = 15.950(6) Å, α = 79.343(6)°, β = 79.061(5)°, γ = 89.849(5)°, Z= 2. The conformation of rings A and B is chair, whereas the conformation of ring C is unsymmetrical twist chair. The carbonyl group at the C20 is coplanar with the benzene ring. The fragment of the ester group occupying the pseudoaxial site of C1 position adopts a zigzag conformation.
Index Abstract
Isosteviol derivative: benzoyloxymethyl (4α,8β,13β)-13-methyl-16-oxo-17-norkauran -18-carbonate ester was synthesized and its crystal structure was determined by X-ray diffraction method.
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Acknowledgments
We are very grateful to the China Ministry of Health Foundation for Scientific Research (project no. WKJ2005-2-022) for financial supports.
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Cai, J., Zhou, W., Chen, J. et al. Synthesis and Crystal Structure of Benzoyloxymethyl (4α,8β,13β)-13-methyl-16-oxo-17-norkauran-18-carbonate Ester. J Chem Crystallogr 39, 108–111 (2009). https://doi.org/10.1007/s10870-008-9435-6
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DOI: https://doi.org/10.1007/s10870-008-9435-6