Abstract
In this paper, hydroxyapatite (HA) particles was modified with long-chain organic silane-Octadecyltrichlorosilane (OTS), and the modified particles were further used for preparing Poly(l-lactic acid) PLLA/HA porous composite. The modified particles were characterized by means of XRD, FTIR, and XPS techniques. Both XPS and FTIR results showed that OTS had been combined with HA, and the formation of P–O–Si bond, a covalent bond, on the HA particle surface was confirmed by XPS. OTS-modified HA particles were used to prepare porous composites by thermally induced phase separation method. The results showed that the composite had an interconnected pore structure with 100–300 μm macropores. With OTS dosage increasing during modification, the mechanical properties of PLLA/OTS-modified HA porous composites increased obviously. These results showed that OTS modification can effectively improve the interface compatibility between HA surface and PLLA.
Similar content being viewed by others
References
E. Landi, A. Tampieri, G. Celotti, S. Sprio, M. Sandri, G. Logroscino, Acta Biomater. 3, 961 (2007). doi:10.1016/j.actbio.2007.05.006
J. Wilson, S.B. Low, J. Appl. Biomater. 3, 123 (1992). doi:10.1002/jab.770030208
H. Qiu, J. Yang, P. Kodali, J. Koh, G.A. Ameer, Biomaterials 27, 5845 (2006). doi:10.1016/j.biomaterials.2006.07.042
R. Labella, M. Braden, S. Deb, Biomaterials 15, 1197 (1994). doi:10.1016/0142-9612(94)90269-0
J.M. Oliveira, M.T. Rodrigues, S.S. Silva, P.B. Malafaya, M.E. Gomes, C.A. Viegasc et al., Biomaterials 27, 6123 (2006). doi:10.1016/j.biomaterials.2006.07.034
H. Wang, Y.B. Li, Y. Zuo, J. Li, S. Ma, L. Cheng, Biomaterials 28, 3338 (2007). doi:10.1016/j.biomaterials.2007.04.014
S.S. Kim, M.S. Park, O. Jeon, C.Y. Choi, B.S. Kim, Biomaterials 27, 1399 (2006). doi:10.1016/j.biomaterials.2005.08.016
G.C. Donga, J.S. Sun, C.H. Yao, G.J. Jiang, C.W. Huang, F.H. Lin, Biomaterials 22, 3179 (2001). doi:10.1016/S0142-9612(01)00070-9
D.N. Misra, Langmuir 7, 2422 (1991). doi:10.1021/la00059a003
J. Ellis, A.M. Jackson, B.P. Scott, A.D. Wilson, Biomaterials 11, 379 (1990). doi:10.1016/0142-9612(90)90090-D
V. Hlady, H. Furedi-Milhofer, J. Coll. Interf. Sci. 69, 460 (1978). doi:10.1016/0021-9797(79)90135-8
P. Schaad, J.M. Thomaan, J.C. Voegel, P. Gramain, J. Coll. Interf. Sci. 164, 291 (1994). doi:10.1006/jcis.1994.1170
H. Tanaka, T. Watanabe, M. Chikazawa, J. Chem. Soc., Faraday Trans. 93, 4377 (1997). doi:10.1039/a705896i
C. Barbot, O. Bouloussa, W. Szymczak, M. Plaschke, G. Buckau, J.P. Durand et al., Colloids Surf. A Physicochem. Eng. Asp. 297, 221 (2007). doi:10.1016/j.colsurfa.2006.10.049
Q. Liu, J.R.D. Wijn, K.D. Groot, A. Clemens, V. Blitterswijk, Biomaterials 19, 1067 (1998). doi:10.1016/S0142-9612(98)00033-7
C.M. Vaz, R.L. Reis, A.M. Cunha, Biomaterials 23, 629 (2002). doi:10.1016/S0142-9612(01)00150-8
C. Santos, R.L. Clarke, M. Braden, F. Guitian, K.W.M. Davy, Biomaterials 23, 1897 (2002). doi:10.1016/S0142-9612(01)00331-3
S.P. Rao, M.D. Poojary, B.W. Elliot, J. Mol. Biol. 222, 89 (1991). doi:10.1016/0022-2836(91)90739-S
A. Tsortos, S. Ohki, A. Zieba, R.E. Baier, G.H. Nancollas, J. Coll. Interf. Sci. 177, 257 (1996). doi:10.1006/jcis.1996.0029
W.J. Weng, G.R. Han, P.Y. Du, G. Shen, Mater. Chem. Phys. 74, 92 (2002). doi:10.1016/S0254-0584(01)00399-6
R. Zhang, W.J. Weng, P.Y. Du, G.L. Zhao, G. Shen, G.R. Han, Polymers Adv. Technol. 15, 425 (2004). doi:10.1002/pat.489
A. S’lo’sarczyk, Z. Paszkiewicz, C. Paluszkiewicz, J. Mol. Struct. 744–747, 657 (2005). doi:10.1016/j.molstruc.2004.11.078
L.G. Benning, V.R. Phoenix, N. Yee, M.J. Tobin, Geochim. Cosmochim. Acta 68, 729 (2004). doi:10.1016/S0016-7037(03)00489-7
P. Massiot, M.A. Centeno, I. Carrizosa, J.A. Odriozola, J. Non-Cryst. Solids 292, 158 (2001). doi:10.1016/S0022-3093(01)00854-7
H. Niida, M. Takahashi, T. Uchino, T. Yoko, J. Non-Cryst. Solids 306, 292 (2002). doi:10.1016/S0022-3093(02)01188-2
B. Menaa, M. Mizuno, M. Takahashi, Y. Tokuda, T. Yoko, J. Solid State Chem. 179, 492 (2006). doi:10.1016/j.jssc.2005.11.001
NIST (1989) Databank in X-ray photoelectron spectroscopy version 1.0
M.S. Sahota, E.L. Short, J. Beynon, J. Non-Cryst. Solids 195, 83 (1996). doi:10.1016/0022-3093(95)00518-8
T. Ishikawa, in Adsorption on New and Modified Inorganic Sorbents, ed. by A. Dabravski, V.A. Tertylkh (Elsevier, Amsterdam, 1996), p. 301
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Yang, C., Cheng, K., Weng, W. et al. OTS-modified HA and its toughening effect on PLLA/HA porous composite. J Mater Sci: Mater Med 20, 667–672 (2009). https://doi.org/10.1007/s10856-008-3604-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10856-008-3604-1