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Post-graphene 2D materials-based antimicrobial agents: focus on fabrication strategies and biosafety assessments

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Abstract

Bacterial infections have caused serious threats to public health nowadays because of the generation of antibiotics-resistant bacteria. Recently, new 2D materials beyond graphene (post-graphene 2D materials, pg-2DMs), such as transition metal dichalcogenides, black phosphorus, layered double hydroxides and MXenes, have been intensively explored for antimicrobial applications on account of their superior physiochemical properties. Here, we provide an up-to-date overview of the post-graphene 2D materials-based antimicrobial agents (pg-2DMs-AA), focusing on (1) the strategies to improve the antimicrobial activities of pg-2DMs-AA and (2) the biosafety assessments of pg-2DMs-AA. Finally, insights regarding the current gaps and outlooks for future opportunities in this field are given as well.

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Acknowledgements

This work was supported by National Key R&D Program of China (2017YFC1600604), National Natural Science Foundation of China (No. 21776136), Jiangsu Synergetic Innovation Center for Advanced Bio-Manufacture (No. XTE1848, XTC1810), Nature Science Foundation of Jiangsu Province (NO. BK20170988), Program for Innovative Research Team in Universities of Jiangsu Province (2015), Top-notch Academic Programs Project of Jiangsu Higher Education Institutions PPZY2015B155, TAPP.

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  1. College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211800, People’s Republic of China

    Jie Zheng, Jingchen Li, Yadong Yu & He Huang

  2. School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, 210023, People’s Republic of China

    Lihui Zhang, Yadong Yu & He Huang

  3. School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, 211816, People’s Republic of China

    Xiaojun Chen

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  1. Jie Zheng
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Zheng, J., Li, J., Zhang, L. et al. Post-graphene 2D materials-based antimicrobial agents: focus on fabrication strategies and biosafety assessments. J Mater Sci 55, 7226–7246 (2020). https://doi.org/10.1007/s10853-020-04507-8

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