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Antifoulant diterpenes produced by the brown seaweed Canistrocarpus cervicornis

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Abstract

This paper reports the antifouling properties of the dichloromethane crude extract (DC) and 3 pure compounds isolated from the Brazilian brown seaweed Canistrocarpus cervicornis against establishment of the mussel Perna perna. DC extract showed a strong inhibition activity against byssal threads. Two natural dolastanes and one seco-dolastane diterpene, namely (4R, 9S, 14S)-4α-acetoxy-9β,14α-dihydroxydolast-1(15),7-diene (1), (4R,7R,14S)-4α,7α-diacetoxy-14-hydroxydolast-1(15),8-diene (2) and isolinearol (3), were isolated from DC extract. Dolastane (1) inhibited 60% of byssal fixation, while compound 2 and the seco-dolastane (3) strongly inhibited (82%) the establishment of P. perna. This is the first report of this type of chemical skeleton in three powerful compounds that could be further explored for the development of antifouling technology.

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Acknowledgments

E.M.B. thanks the National Brazilian Research Council (CNPq) for providing a PhD fellowship, and R.C.P. and V.L.T. thank CNPq for a research productivity fellowship. We are grateful to Dr. Maria Tereza M. Széchy and MSc Joel Campos De Paula for help in the collection and identification of seaweeds.

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Authors and Affiliations

  1. Pós-Graduação em Química Orgânica, Instituto de Química, Universidade Federal Fluminense, CEP 24020–150, Niterói, RJ, Brazil

    Éverson Miguel Bianco, Valéria Laneuville Teixeira & Renato Crespo Pereira

  2. Departamento de Biologia Marinha, Instituto de Biologia, Universidade Federal Fluminense, P.O. Box 100.644, CEP 24001–970, Niterói, RJ, Brazil

    Ricardo Rogers, Valéria Laneuville Teixeira & Renato Crespo Pereira

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  1. Éverson Miguel Bianco
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  2. Ricardo Rogers
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  3. Valéria Laneuville Teixeira
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  4. Renato Crespo Pereira
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Correspondence to Renato Crespo Pereira.

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Bianco, É.M., Rogers, R., Teixeira, V.L. et al. Antifoulant diterpenes produced by the brown seaweed Canistrocarpus cervicornis . J Appl Phycol 21, 341–346 (2009). https://doi.org/10.1007/s10811-008-9374-9

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  • DOI: https://doi.org/10.1007/s10811-008-9374-9

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