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Comparison of formulas and methods for high myopia patients requiring intraocular lens powers less than six diopters

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Abstract

Purpose

To determine the best method to minimize postoperative hyperopia and achieve mild myopia in patients requiring low-powered (<6.00 D) MN60MA intraocular lenses (IOLs).

Methods

This retrospective non-comparative case series consists of 32 eyes (20 patients). Postoperative spherical equivalent (SE) refractions were compared using four methods: standard formulas with varying target refractions (Haigis −1.00 D, Hoffer Q −1.75 D, Holladay 1 −1.50 D and SRK/T −1.00 and −1.25 D), axial length adjustment methods for standard formulas targeted for both plano and −0.50 D, Barrett Universal II formula and the Haigis formula using separate constants for plus and minus IOLs (Haigis +/−). SE (mean, standard deviation, median, range), median absolute error (MedAE), prediction errors, percentage SE less than 0.25 D and greater than −1.00 D, percentage SE within ±0.50 and ±1.00 D of the targeted refraction were calculated.

Results

All methods and formulas gave acceptable mean SE refractions ranging from −0.04 to −0.68 D. The Barrett Universal II, Haigis +/−, standard Haigis formula targeted for −1.00 D and the Holladay 1 formula targeted for −1.50 D met stricter criteria of final SE between 0.25 and −1.00 D in 94–100% of eyes and MedAE between 0.37 and 0.51 D. Other methods had more myopic or hyperopic outliers.

Conclusions

For these eyes with high myopia, the Barrett Universal II, Haigis +/−, standard Haigis targeted for −1.00 D and the standard Holladay 1 targeted for −1.50 D formulas produce the best results exceeding established benchmark criteria and minimizing hyperopic surprises.

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Correspondence to Harry S. Geggel.

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The author declares that he has no conflict of interest. The author certifies that he has no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Retrospective study: For this type of study, formal consent is not required.

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Geggel, H.S. Comparison of formulas and methods for high myopia patients requiring intraocular lens powers less than six diopters. Int Ophthalmol 38, 1497–1504 (2018). https://doi.org/10.1007/s10792-017-0611-6

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  • DOI: https://doi.org/10.1007/s10792-017-0611-6

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