Abstract
Popularity of herbal drugs is increasing all over the world because of lesser side effects as compared to synthetic drugs. Besides, it costs less and easily available to poor people particularly in developing countries. But quality assurance of herbal drugs is very necessary prior to its use. Because in today's polluted environment, even herbal drugs are not safe. Berberis spp. is very important medicinal plant, having various medicinal properties. It is also included in Indian and British pharmacopoeias. Its demand is quite high in herbal drug market. So, to check the quality of market samples of this drug, ten different samples were procured from different drug markets of India for heavy metal estimation. Besides, genuine samples of four species of Berberis viz. B. aristata, B. chitria, B. lycium, B. asiatica were also collected from natural habitats to compare heavy metal concentration in both market and genuine samples. It was found that market samples were much more contaminated than genuine samples. Lead (Pb) concentration is far beyond from WHO permissible limit (10 ppm) for herbal drugs, reaching to maximum 49.75 ppm in Amritsar market sample. Likewise, concentration of all other metals like Cd, Cr and Ni were also very high in market samples as compared to genuine samples.
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References
Akhter, M. H., Sabir, M. and Bhide, N. K.: 1977, ‘Anti-inflammatory effect of berberine on rats injected locally with cholera toxin’, Indian. J. Med. Res. 65, 133–144.
Barman, S. C., Kisku, G. C. and Bhargava, S. K.: 1999, ‘Accumulation of heavy metals in vegetables, pulse and wheat grown in fly ash amended soil’, J. Environ. Biol. 20, 15–18.
Barman, S. C. and Lal M. M.: 1994, ‘Accumulation of heavy metals (Zn, Cu, Cd and Pb) in soil and cultivated vegetables and weeds grown in industrially polluted fields’, J. Environ. Biol. 15, 107–115.
Bussotti, F., Rinallo, C., Grossoni, P., Gellini, R., Pantani, F. and Del Panta, S.: 1983, ‘Degrado delta egetazione costiera nella Tenuta di S, Rossore, La Provinca Pisana’, Spec. Parco. Nat. igliarino. S. Rossore. Massaciuccoli. e arre. protette. 9, 46–52.
Chizzola, R. and Franz, C.: 1996, ‘Metallic trace elements in medicinal and aromatic plants from Austria’, J. Appl. Bot. 70, 52–56.
Chopra, R. N., Chopra, T. C., Handa, K. L. and Kapoor, L. D.: 1958, Indigenous Drugs of India, U.N. Dhar and sons Pvt. Ltd.
Dean, J. G., Bosqui, F. L. and Lanouette, V. H.: 1972, ‘Removing heavy metals from waste water’, Environ. Sci. Technol. 6, 518–522.
Forstner, U. and Wittmann, G. T. W.: 1979, Metal Pollution in Aquatic Environment, Springer, Berlin, Heidelberg, New York.
Hunter, B. A., Johnson, M. S. and Thompson, D. J.: 1987, ‘Ecotoxicology of copper and cadmium in a contaminated grassland ecosystem. I. Soil and vegetation contamination’, J. Appl. Ecol. 24, 573–586.
Ju, H. and Han, Z.: 1990, ‘Anti oxidant effect of berberine’, Zhongguo. Yaoli. Xuebao. 11, 539–541.
Kirtikar, K. R. and Basu, B. D.: 1933, Indian Medicinal Plants I, Lalit Mohan Basu and Co., Allahabad.
Kwapulinski, J., Miroslawaki, J., Wiechula, D., Rochel, R., Burczyk, J., Sowada, B. and Iwanek, K.: 1996, ‘The use of ecotoxicological parameters for estimation of quality of the medicinal plants yielding areas’, Bromatologia. I. Chemia. Toksykolo. Giczna. 29, 243–252.
Markert, B.: 1994, ‘Plants as biomonitors — Potential advantages and problems’, in: D.C. Adriano, Z.S. Chen and S.S. Yang (eds), Biogeochemistry of Trace Elements, Science and Technology Letters. Northwood, NY, pp. 601–613.
Nriagu, J. O. and Pacyna, J. M.: 1988, ‘Quantitative assessment of worldwide contamination of air, water and soils by trace metals’, Nature 333, 134–139.
Rai, V., Kakkar, P., Khatoon, S., Rawat, A. K. S. and Mehrotra, S.: 2001a, ‘Heavy metal accumulation in some herbal drugs’, Pharmaceut. Biol. 39, 384–387.
Rai, V., Agarwal, M., Khatoon, S., Rawat, A. K. S. and Mehrotra, S.: 2001b, ‘Estimation of Co and Mn in some medicinal plants’, Bull. Environ. Contam. Toxicol. 66, 427–432
Sharma, B. K. and Habib, I.: 1995, ‘Differential bioaccumulation of Mg, Pb, Cr and Zn in some Rabi crops and elemental bioaccumulation, metabolite concentration in component parts of Cicer arientinum var. C-235 under irrigational impact of rubber factory effluent’, J. Indian. Bot. Soc. 74, 197–204.
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Srivastava, S.K., Rai, V., Srivastava, M. et al. Estimation of Heavy Metals in Different Berberis Species and Its Market Samples. Environ Monit Assess 116, 315–320 (2006). https://doi.org/10.1007/s10661-006-7395-x
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DOI: https://doi.org/10.1007/s10661-006-7395-x