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Worldwide Burden of Gastric Cancer Attributable to Tobacco Smoking in 2012 and Predictions for 2020

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An Erratum to this article was published on 10 July 2015

Abstract

Background

The heterogeneous patterns and trends in tobacco consumption contribute to regional and gender differences in the burden of gastric cancer attributable to smoking.

Aims

To estimate the proportion and absolute number of gastric cancer cases that can be attributed to smoking in different countries, in 2012 and 2020.

Methods

Population attributable fractions (PAFs) were computed for 118 countries, using data of smoking prevalence in 2002 and 2011 and published estimates of the magnitude of the association between smoking and gastric cancer, assuming a time lag of ≈10 years.

Results

For men, the highest PAF estimates in 2012 were observed in Eastern Asia and the lowest in North America, whereas for women the highest were in Western Europe and the lowest in Africa. Very high Human Development Index (HDI) countries presented the lowest median PAF in men (very high vs. high, medium, and low HDI: 17.2 vs. 20.8 %, p = 0.014) and the highest median PAF in women (very high vs. high, medium, and low HDI: 4.3 vs. 1.8 %, p < 0.001). Estimates for 2020 show a decrease in median PAFs, but the estimated absolute number of cases attributable to smoking in the countries analyzed increased for men (≈154,000 vs. ≈160,000) and decreased for women (≈6200 vs. ≈5600).

Conclusions

Smoking accounts for a larger number of gastric cancer cases among men, and gender differences are expected to increase in the next decade, despite the decrease in PAFs. Intensified efforts to control smoking are needed to further reduce the burden of gastric cancer.

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Acknowledgments

This work was supported by “Fundação para a Ciência e a Tecnologia” (PTDC/SAU-EPI/122460/2010 and SFRH/BPD/75918/2011).

Conflict of interest

None.

Author information

Authors and Affiliations

  1. EPIUnit – Institute of Public Health, University of Porto, Rua das Taipas 135, 4050-600, Porto, Portugal

    Bárbara Peleteiro, Clara Castro, Samantha Morais, Ana Ferro & Nuno Lunet

  2. Department of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto Medical School, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal

    Bárbara Peleteiro & Nuno Lunet

  3. North Region Cancer Registry (RORENO) – Portuguese Oncology Institute, Rua Dr. António Bernardino de Almeida, 4200-072, Porto, Portugal

    Clara Castro

Authors
  1. Bárbara Peleteiro
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  2. Clara Castro
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  3. Samantha Morais
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  4. Ana Ferro
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  5. Nuno Lunet
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Corresponding author

Correspondence to Bárbara Peleteiro.

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Peleteiro, B., Castro, C., Morais, S. et al. Worldwide Burden of Gastric Cancer Attributable to Tobacco Smoking in 2012 and Predictions for 2020. Dig Dis Sci 60, 2470–2476 (2015). https://doi.org/10.1007/s10620-015-3624-x

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  • DOI: https://doi.org/10.1007/s10620-015-3624-x

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