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Clinical Characteristics of Small Bowel Tumors Diagnosed by Double-Balloon Endoscopy: KASID Multi-Center Study

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Abstract

Background

Small bowel tumors are relatively rare, and their confirmative diagnosis before surgery is not easy.

Aims

This study was performed to investigate the clinical characteristics of patients with small bowel tumors who received double-balloon enteroscopy (DBE). Secondary end points were to evaluate the usefulness and safety of DBE for the diagnosis of patients with suspected SB tumors derived from other previous procedures.

Methods

We retrospectively analyzed consecutive DBE examinations to explore the small intestine in eight university hospitals over a 5-year period.

Results

A total of 877 DBE examinations (per oral 487, per anal 390) were performed in 645 patients (405 males, mean age 48.2 years). Small bowel tumors were diagnosed in 112 patients (17.4%), of which 38 patients had benign polyps, 29 had gastrointestinal stromal tumors/leiomyomata, 18 had lymphomas, 14 had adenocarcinomas, five had metastatic or invasive cancers, five had lipomas, and three patients had cystic tumors. The main reasons for DBE among patients with small bowel tumors were obscure gastrointestinal bleeding (OGIB, 40.2%) followed by abnormal imaging study (25.2%). The concordance rate of diagnoses based on DBE with diagnoses based on small bowel follow-through, CT, and capsule endoscopy among patients with small bowel tumors was 68.9% (42/61), 75.3% (70/93), and 78.3% (18/23), respectively. Therapeutic plans were changed due to the DBE results in 64.2% of patients with small bowel tumors.

Conclusions

Approximately one-sixth of patients who received DBE had small bowel tumors, and the most common reason for DBE among patients with small bowel tumors was OGIB. DBE is a useful method for the confirmative diagnosis of small bowel tumors and has a good clinical impact on therapeutic plans and short-term clinical results.

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Acknowledgments

This study was supported by the 2007 Fujinon Grant, Korean Association for the Study of Intestinal Diseases.

Conflicts of interest

Drs Bo-In Lee, Hwang Choi, Kyu-Yong Choi, Jeong-Sik Byeon, Hyun-Joo Jang, Chang-Soo Eun, Jae Hee Cheon, Sung Jae Shin, Jin-Oh Kim, Moon-Sung Lee, and Jai-Hyun Choi have no conflicts of interest or financial ties to disclose.

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Authors and Affiliations

  1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea

    Bo-In Lee, Hwang Choi & Kyu-Yong Choi

  2. Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea

    Jeong-Sik Byeon

  3. Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea

    Hyun-Joo Jang

  4. Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea

    Chang-Soo Eun

  5. Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea

    Jae Hee Cheon

  6. Department of Gastroenterology, Ajou University College of Medicine, Suwon, Korea

    Sung Jae Shin

  7. Institute for Digestive Research, Digestive Disease Center, Soon Chun Hyang University Hospital, Seoul, Korea

    Jin-Oh Kim & Moon-Sung Lee

  8. Department of Internal Medicine, Institute of Digestive Disease and Nutrition, Korea University College of Medicine, Seoul, Korea

    Jai-Hyun Choi

  9. Department of Internal Medicine, Incheon St. Mary’s Hospital, The Catholic University of Korea, #665, Bupyeong-dong, Bupyeong-gu, Incheon, 403-720, Korea

    Hwang Choi

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  1. Bo-In Lee
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  2. Hwang Choi
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  3. Kyu-Yong Choi
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  4. Jeong-Sik Byeon
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  5. Hyun-Joo Jang
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  6. Chang-Soo Eun
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  7. Jae Hee Cheon
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  8. Sung Jae Shin
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  9. Jin-Oh Kim
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  10. Moon-Sung Lee
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  11. Jai-Hyun Choi
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Corresponding author

Correspondence to Hwang Choi.

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Lee, BI., Choi, H., Choi, KY. et al. Clinical Characteristics of Small Bowel Tumors Diagnosed by Double-Balloon Endoscopy: KASID Multi-Center Study. Dig Dis Sci 56, 2920–2927 (2011). https://doi.org/10.1007/s10620-011-1839-z

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  • DOI: https://doi.org/10.1007/s10620-011-1839-z

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