Abstract
We planned to investigate the recent trends for colorectal cancer (CRC) screening in human immunodeficiency virus (HIV) as compared to non-HIV by interviewing consecutive patients in outpatient clinics during September 2007. Out of a total of 300 patients interviewed, 205 met the inclusion criteria. One hundred and fourteen were HIV-infected, while 91 were non-HIV. HIV received more office visits per year. Despite the high incidence of adenomas on screening colonoscopy, HIV patients were less likely to undergo any type of CRC screening test. A higher number (≥10) of annual clinic visits and the presence of co-morbid conditions were associated with being up-to-date for CRC screening in HIV patients. Conclusion CRC screening is underutilized in HIV patients. Multiple office visits per year are associated with being up-to-date for CRC screening. Hence, increasing patients’ compliance with office visits and educating them about the importance of CRC screening may indirectly increase compliance with CRC screening.
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References
Palella FJ Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med. 1998;338:853–860.
Palella FJ Jr, Deloria-Knoll M, Chmiel JS, et al. Survival benefit of initiating antiretroviral therapy in HIV-infected persons in different CD4+ cell strata. Ann Intern Med. 2003;138:620–626.
Murphy EL, Collier AC, Kalish LA, et al. Highly active antiretroviral therapy decreases mortality and morbidity in patients with advanced HIV disease. Ann Intern Med. 2001;135:17–26.
Porter K, Babiker A, Bhaskaran K, et al. Determinants of survival following HIV-1 seroconversion after the introduction of HAART. Lancet. 2003;362:1267–1274.
Mocroft A, Ledergerber B, Katlama C, et al. Decline in the AIDS and death rates in the EuroSIDA study: an observational study. Lancet. 2003;362:22–29.
Wood E, Low-Beer S, Bartholomew K, et al. Modern antiretroviral therapy improves life expectancy of gay and bisexual males in Vancouver’s West End. Can J Public Health. 2000;91:125–128.
Manfredi R. HIV disease and advanced age: an increasing therapeutic challenge. Drugs Aging. 2002;19:647–669.
Lai D, Hardy RJ. An update on the impact of HIV/AIDS on life expectancy in the United States. AIDS. 2004;18:1732–1734.
Keiser O, Taffé P, Zwahlen M, et al. All cause mortality in the Swiss HIV Cohort Study from 1990 to 2001 in comparison with the Swiss population. AIDS. 2004;18:1835–1843.
Jemal A, Tiwari RC, Murray T, et al. Cancer statistics, 2004. CA Cancer J Clin. 2004;54:8–29.
HIV Epidemiology Program. New York City Department of Health and Mental Hygiene. Home page at: http://www.nyc.gov/html/doh/html/dires/hivepi.shtml.
Pignone M, Rich M, Teutsch SM, et al. Screening for colorectal cancer in adults at average risk: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med. 2002;137:132–141.
Smith RA, Cokkinides V, Eyre HJ. American Cancer Society guidelines for the early detection of cancer, 2004. CA Cancer J Clin. 2004;54:41–52.
Winawer S, Fletcher R, Rex D, et al. Colorectal cancer screening and surveillance: clinical guidelines and rationale—update based on new evidence. Gastroenterology. 2003;124:544–560.
Rex DK, Johnson DA, Lieberman DA, et al. Colorectal cancer prevention 2000: screening recommendations of the American College of Gastroenterology. Am J Gastroenterol. 2000;95:868–877.
American Society for Gastrointestinal Endoscopy. Guidelines for colorectal cancer screening and surveillance. Gastrointest Endosc. 2000;51:777–782.
Reinhold JP, Moon M, Tenner CT, et al. Colorectal cancer screening in HIV-infected patients 50 years of age and older: missed opportunities for prevention. Am J Gastroenterol. 2005;100(8):1805–1812.
Newcomb PA, Norfleet RG, Storer BE, et al. Screening sigmoidoscopy and colorectal cancer mortality. J Natl Cancer Inst. 1992;84:1572–1575.
Pignone M, Saha S, Hoerger T, et al. Cost-effectiveness analyses of colorectal cancer screening: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2002;137:96–104.
Cooksley CD, Hwang LY, Waller DK, et al. HIV-related malignancies: community-based study using linkage of cancer registry and HIV registry data. Int J STD AIDS. 1999;10:795–802.
Bedimo R, Chen RY, Accortt NA, et al. Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989–2002. Clin Infect Dis. 2004;39:1380–1384.
Yegüez JF, Martinez SA, Sands DR, et al. Colorectal malignancies in HIV-positive patients. Am Surg. 2003;69:981–987.
Bini EJ, Park J, Francois F. Use of flexible sigmoidoscopy to screen for colorectal cancer in HIV-infected patients 50 years of age and older. Arch Intern Med. 2006;166(15):1626–1631.
Chiao EY, Krown SE. Update on non-acquired immunodeficiency syndrome-defining malignancies. Curr Opin Oncol. 2003;15:389–397.
Cappell MS, Yao F, Cho KC. Colonic adenocarcinoma associated with the acquired immune deficiency syndrome. Cancer. 1988;62:616–619.
Klugman AD, Schaffner J. Colon adenocarcinoma in HIV infection: a case report and review. Am J Gastroenterol. 1994;89:254–256.
Demopoulos BP, Vamvakas E, Ehrlich JE, et al. Non-acquired immunodeficiency syndrome-defining malignancies in patients infected with human immunodeficiency virus. Arch Pathol Lab Med. 2003;127:589–592.
Wasserberg N, Nunoo-Mensah JW, Gonzalez-Ruiz C, et al. Colorectal cancer in HIV-infected patients: a case control study. Int J Colorectal Dis. 2007;22(10):1217–1221.
Beach MC, Keruly J, Moore RD. Is the quality of the patient-provider relationship associated with better adherence and health outcomes for patients with HIV? J Gen Intern Med. 2006;21(6):661–665.
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We especially thank Dr. Marlyn Martinaar, Dr. Vilma Vas, and Dr. Eric A Jaffe for their help and support during the project.
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Iqbal, S., Browne-McDonald, V. & Cerulli, M.A. Recent Trends for Colorectal Cancer Screening in HIV-Infected Patients. Dig Dis Sci 55, 761–766 (2010). https://doi.org/10.1007/s10620-009-0774-8
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DOI: https://doi.org/10.1007/s10620-009-0774-8