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Effects of Saccharomyces boulardii on Intestinal Mucosa

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Abstract

Saccharomyces boulardii (S. boulardii) is a non-pathogenic biotherapeutic agent, widely prescribed in a lyophilized form in many countries over the world. S. boulardii acts as a shuttle liberating effective enzymes, proteins and trophic factors during its intestinal transit that improve host immune defenses, digestion, and absorption of nutrients. In addition, S. boulardii secretes during its intestinal transit polyamines, mainly spermine and spermidine that regulate gene expression and protein synthesis. In this review, we will focus on the interactions of the yeast with the host intestinal mucosa.

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Acknowledgments

This work was supported by the Fonds de Recherche Scientifique Médicale (Grants 9.4524.91-4.511.92) and by a grant from Biocodex Laboratories, Montrouge, France.

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Authors and Affiliations

  1. Laboratory of Pediatric Gastroenterology and Nutrition, Unit of Pediatric Research, Université Catholique de Louvain, Louvain, Belgium

    Jean-Paul Buts & Nadine De Keyser

  2. Cliniques Universitaires Saint-Luc, 10 avenue Hippocrate, B-1200, Bruxelles, Belgique

    Jean-Paul Buts

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  1. Jean-Paul Buts
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  2. Nadine De Keyser
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Correspondence to Jean-Paul Buts.

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Buts, JP., De Keyser, N. Effects of Saccharomyces boulardii on Intestinal Mucosa. Dig Dis Sci 51, 1485–1492 (2006). https://doi.org/10.1007/s10620-005-9016-x

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