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New Indole Alkaloids from the Sponge Plakortis sp.

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Chemistry of Natural Compounds Aims and scope

An unprecedented bis-indole 1, a novel indole alkaloid 2, and some known indole-related compounds 3–5 have been isolated from the sponge Plakortis sp. collected from Zampa in Okinawa. Their structures were elucidated by spectroscopic analysis. These metabolites showed cytotoxic activity against P388 leukemia and B16 melanoma cells.

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Acknowledgment

This work was supported in part by Grants-in-Aid for Scientific Research (No. 21221009) from the Ministry of Education, Culture, Sports, Science, and Technology (MEXT), Japan.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University, 16680, Bogor, Indonesia

    Novriyandi Hanif

  2. Department of Chemistry, Faculty of Science, Kanagawa University, 259-1293, Hiratsuka, Japan

    Kaoru Yamada, Yoshinori Kawazoe & Daisuke Uemura

  3. Institute for Chemistry and Biology of the Marine Environment (ICBM), University of Oldenburg, Schleusenstrase 1, 26382, Wilhelmshaven, Germany

    Makoto Kitamura

  4. Naturalis Biodiversity Center, P. O. Box 9517, 2300 RA, Leiden, The Netherlands

    Nicole J. de Voogd

Authors
  1. Novriyandi Hanif
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  2. Kaoru Yamada
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  3. Makoto Kitamura
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  4. Yoshinori Kawazoe
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  5. Nicole J. de Voogd
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  6. Daisuke Uemura
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Corresponding author

Correspondence to Novriyandi Hanif.

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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2015, pp. 973–975.

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Hanif, N., Yamada, K., Kitamura, M. et al. New Indole Alkaloids from the Sponge Plakortis sp.. Chem Nat Compd 51, 1130–1133 (2015). https://doi.org/10.1007/s10600-015-1508-0

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  • DOI: https://doi.org/10.1007/s10600-015-1508-0

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