Skip to main content
Log in

Three New Ginsenosides from the Heat-Processed Roots of Panax ginseng

  • Published:
Chemistry of Natural Compounds Aims and scope

Three new ginsenosides were isolated from heat-processed ginseng roots. Their structures were determined to be 3β,12β,25-trihydroxydammar-20E(22)-ene-3-O-β-D-glucopyranoside, 3β,12β,23-trihydroxy-24,25-epoxydammar-20E(22)-ene-3-O-β-D-glucopyranosyl(1 → 2)-β-D-glucopyranoside, and 3β,6α,12β-trihydroxydammar-20E(22),24-diene-6-O-β-D-glucopyranosyl-12-O-β-D-glucopyranoside based on spectroscopic evidence. The compounds were named ginsenosides Rh10, Rg11, and 12-O-glucoginsenoside-Rh4, respectively.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. A. F. G. Cicero, G. Vitale, G. Savino, and R. Arletti, Phytother. Res., 17, 174 (2003).

    Article  PubMed  CAS  Google Scholar 

  2. H. Sun, Z. Yang, and Y. Ye, Int. Immunopharm., 6, 14 (2005).

    Article  Google Scholar 

  3. Wei Li, Jian Yuan Yin, Zhong Yi Cong, Ying Liu, Ying Zhang, Yan Yan Li, and Qin Meng, Chem. Nat. Compd., 48, 1017 (2013); L. N. Atopkina and V. A. Denisenko, Chem. Nat. Compd., 48, 1111 (2013).

  4. D. Y. Lee, J. G. Cho, M. K. Lee, J. W. Lee, H. J. Park, Y. H. Lee, D. C. Yang, and N. I. Baek, J. Ginseng Res., 32, 291 (2009).

    Google Scholar 

  5. J. G. Cho, M. K. Lee, J. W. Lee, H. J. Park, D. Y. Lee, Y. H. Lee, D. C. Yang, and N. I. Baek, J. Ginseng Res., 34, 113 (2010).

    Article  CAS  Google Scholar 

  6. C. R. Lee, W. K. Whang, C. G. Shin, H. S. Lee, S. T. Han, B. O. Im, and S. K. Ko, Korean J. Food Sci. Technol., 30, 847 (2004).

    Google Scholar 

  7. W. Y. Kim, J. M. Kim, S. B. Han, S. K. Lee, N. D. Kim, M. K. Park, C. K. Kim, and J. H. Park, J. Nat. Prod., 63, 1702 (2000).

    Article  PubMed  CAS  Google Scholar 

  8. I. H. Park, N. Y. Kim, S. B. Han, J. M. Kim, S. W. Kwon, H. J. Kim, M. K. Park, and J. H. Park, Arch. Pharm. Res., 25, 428 (2002).

    Article  PubMed  CAS  Google Scholar 

  9. Y. J. Ban, B. W. Yang, M. Y. Baik, Y. T. Hahm, and B. Y. Kim, J. Korean Soc. Appl. Biol. Chem., 53, 71 (2010).

    Article  CAS  Google Scholar 

  10. S. K. Ko, O. S. Cho, H. M. Bae, B. O. Im, O. H. Lee, and B. Y. Lee, J. Korean Soc. Appl. Biol. Chem., 54, 154 (2011).

    Article  CAS  Google Scholar 

  11. J. M. Hur and D. J. Kim, J. Appl. Biol. Chem., 54, 15 (2011).

    Article  CAS  Google Scholar 

  12. N. I. Baek, D. S. Kim, Y. H. Hui, J. D. Park, C. B. Lee, and S. I. Kim, Planta Med., 62, 86 (1996).

    Article  PubMed  CAS  Google Scholar 

  13. D. Q. Dou, Y. J. Chien, L. H. Liang, F. G. Pang, N. Shimizu, and T. Takeda, Chem. Pharm. Bull., 49, 442 (2001).

    Article  PubMed  CAS  Google Scholar 

  14. D. S. Kim, N. I. Baek, J. D. Park, Y. H. Lee, S. Y. Jeong, C. B. Lee, and S. I. Kim, Yakhak Hoeji, 39, 85 (1995).

    CAS  Google Scholar 

  15. G. T. Chen, M. Yang, Y. Song, Z. Q. Lu, J. Q. Zhang, H. L. Huang, L. J. Wu, and D. A. Guo, Appl. Microbiol. Biotechnol., 77, 1345 (2008).

    Article  PubMed  CAS  Google Scholar 

  16. D. Dou, W. Li, N. Guo, R. Fu, Y. Pei, K. Koike, and T. Nikaido, Chem. Pharm. Bull., 54, 751 (2006).

    Article  PubMed  CAS  Google Scholar 

  17. R. W. Teng, H. Z. Li, D. Z. Wang, and C. R. Yang, Helv. Chim. Acta, 87, 1270 (2004).

    Article  CAS  Google Scholar 

  18. R. W. Teng, H. Z. Li, X. M. Zhang, X. K. Liu, D. Z. Wang, and C. R. Yang, Chin. Chem. Lett., 12, 239 (2001).

    CAS  Google Scholar 

  19. L. N. Atopkina and V. A. Denisenko, Chem. Nat. Compd., 42, 452 (2006).

    Article  CAS  Google Scholar 

  20. S. Yahara, R. Kasai, and O. Tanaka, Chem. Pharm. Bull., 25, 2041 (1977).

    Article  CAS  Google Scholar 

Download references

Acknowledgment

This research was supported by Cooperative Research Program for Agricultural Science & Technology Development (PJ009544), Rural Development Administration, Republic of Korea.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Nam-In Baek.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2013, pp. 758–762.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cho, JG., Lee, DY., Shrestha, S. et al. Three New Ginsenosides from the Heat-Processed Roots of Panax ginseng . Chem Nat Compd 49, 882–887 (2013). https://doi.org/10.1007/s10600-013-0769-8

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10600-013-0769-8

Keywords

Navigation