A novel macrocarpal (macrocarpal M) together with the grandinol (a known plant metabolite of Eucalptus spp.) were isolated from a methanolic extract of sawfly larvae sp. indet. (Australian sawfly, Hymenoptera:Symphyta) using the developed reversed-phase high-performance liquid chromatography (RP-HPLC) method. To the best of our knowledge, this macrocarpal M is found to have high levels of antimicrobial activity for the first time. The structures of two compounds were identified by ESI-MS, 1H NMR, 13C NMR, and 2D NMR.
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Acknowledgment
We thank the China Scholarship Council for funding to Prof. Yin. We thank Mr. M. Neave, A. Calder, and A. Strazynski of CSIRO Entomology for sample collection. We thank Dr. John LaSalle of CSIRO Entomology for taxonomic identification. We also thank Ms. J. M. Rothschild, Research School of Chemistry, ANU for mass spectra record.
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Published in Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2013, pp. 38–41.
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Yin, W., Zhao, C., Liao, C. et al. Preparative Isolation of Novel Antimicrobial Compounds from Pergidae sp. by Reversed-Phase High-Performance Liquid Chromatography. Chem Nat Compd 49, 41–45 (2013). https://doi.org/10.1007/s10600-013-0501-8
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DOI: https://doi.org/10.1007/s10600-013-0501-8