A series of new N-acylsubstituted thioureas, the compositions and structures of which were determined by IR and PMR spectroscopy and mass spectrometry, were synthesized from the alkaloid anabasine. The crystal structure of one of the products, N-(anabasino-1-thiocarbonyl)furan-2-carboxamide, was confirmed by x-ray structure analysis. It was also shown that this compound exhibited moderate antibacterial activity.
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Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 183–185, March–April, 2009.
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Kulakov, I.V., Nurkenov, O.A., Turdybekov, D.M. et al. Synthesis of thiourea derivatives of the alkaloid anabasine and crystal structure of N-(anabasino1-thiocarbonyl)furan-2-carboxamide. Chem Nat Compd 45, 209–212 (2009). https://doi.org/10.1007/s10600-009-9284-3
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DOI: https://doi.org/10.1007/s10600-009-9284-3