Skip to main content
SpringerLink
Log in

Synthesis of Thiourea Derivatives of the Alkaloids Anabasine, Cytisine, and d-Pseudoephedrine. Crystal Structure of N-ethyl-N-Anabasinocarbothioamide

  • Published:
Chemistry of Natural Compounds Aims and scope

Ethylthiourea derivatives of the alkaloids anabasine, cytisine, and d-pseudoephedrine were synthesized using ethylisothiocyanate. Their structures were proven using PMR spectroscopy. The molecular structure of N-ethyl-N-anabasinocarbothioamide was established by an X-ray crystal structure analysis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. M. D. Mashkovskii, Drugs [in Russian], Moscow, 2012, 1216 pp.

  2. O. A. Nurkenov, S. D. Fazylov, I. V. Kulakov, and L. A. Musina, Alkaloid Anabasine and Its Derivatives [in Russian], Glasir, Karaganda, 2010, 224 pp.

  3. O. A. Nurkenov, I. V. Kulakov, and S. D. Fazylov, Synthetic Transformations of the Alkaloid Cytisine [in Russian], Glasir, Karaganda, 2012, 210 pp.

  4. O. A. Nurkenov, S. D. Fazylov, K. M. Turdybekov, and M. Z. Muldakhmetov, Ephedrine Alkaloids and Their Derivatives [in Russian], Glasir, Karaganda, 2014, 264 pp.

  5. O. A. Nurkenov, Zh. B. Satpaeva, S. D. Fayzlov, and G. Zh. Karipova, in: International Scientific Conference “Critical Problems in the Chemistry of Natural Compounds” [in Russian], Tashkent, 2013, p. 19.

  6. F. H. Allen, O. Kennard, D. G. Watson, L. Brammer, A. G. Orpen, and R. Taylor, J. Chem. Soc. Perkin Trans. 2, S1-S19 (1987).

    Article  Google Scholar 

  7. M. Wojciechowska-Nowak, W. Boczon, U. Rychlewska, and B. Warzajtis, J. Mol. Struct., 840, 44 (2007).

    Article  CAS  Google Scholar 

  8. M. Wojciechowska-Nowak, B. Jasiewicz, W. Boczon, B. Warzajtis, and U. Rychlewska, J. Mol. Struct., 997, 15 (2011).

    Article  CAS  Google Scholar 

  9. Yu. V. Zefirov and P. M. Zorkii, Zh. Strukt. Khim., 15 (1), 118 (1974).

    CAS  Google Scholar 

  10. J. J. P. Stewart, J. Comput. Chem., 10 (2), 209 (1989).

    Article  CAS  Google Scholar 

  11. Cambridge Crystallographic Database, Cambridge, 2015.

  12. SMART V5.051 and SAINT V5.00, Bruker AXS Inc., Madison, USA, 2005.

  13. G. M. Sheldrick, SADABS, Bruker AXS Inc., Madison, USA, 2008.

  14. G. M. Sheldrick, Acta Crystallogr., Sect. A: Found. Crystallogr., 64, 112 (2008).

Download references

Author information

Authors and Affiliations

  1. Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, 1 Alikhanova St., Karaganda, 100008, Kazakhstan

    O. A. Nurkenov, Zh. B. Satpaeva & S. D. Fazylov

  2. Sh. Ualikhanov Kokshetau State University, 76 Abaya St., Kokshetau, 020000, Republic of Kazakhstan

    T. M. Seilkhanov

  3. Karaganda State Technical University, 56 B. Mira, Karaganda, 100027, Republic of Kazakhstan

    K. M. Turdybekov, D. M. Turdybekov & A. M. Gazaliev

  4. Karaganda State Medical University, 40 Gogolya St., Karaganda, Republic of Kazakhstan

    S. B. Akhmetova & A. S. Makhmutova

Authors
  1. O. A. Nurkenov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Zh. B. Satpaeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. D. Fazylov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. T. M. Seilkhanov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. K. M. Turdybekov
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. D. M. Turdybekov
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. S. B. Akhmetova
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. A. S. Makhmutova
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. A. M. Gazaliev
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2016, pp. 243–245.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nurkenov, O.A., Satpaeva, Z.B., Fazylov, S.D. et al. Synthesis of Thiourea Derivatives of the Alkaloids Anabasine, Cytisine, and d-Pseudoephedrine. Crystal Structure of N-ethyl-N-Anabasinocarbothioamide. Chem Nat Compd 52, 276–279 (2016). https://doi.org/10.1007/s10600-016-1613-8

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10600-016-1613-8

Keywords

Search

Navigation