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Synthesis of novel 6-methyl-4-sulfanylfuro[3,4-с]pyridin-3(1H)-ones

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Chemistry of Heterocyclic Compounds Aims and scope

Alkylation of 6-methyl-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-one in an alkaline medium proceeds regioselectively at the sulfur atom to form sulfanyl derivatives.

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The study was supported by the Ministry of Agriculture of the Russian Federation (topic AAAA-A16-116021110069-8) and the Ministry of Education and Science of the Russian Federation (grant 4.6087.2017/ БЧ).

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Authors and Affiliations

  1. Kuban State Agrarian University, 13 Kalinina St., Krasnodar, 350044, Russia

    Elena А. Kaigorodova

  2. Kuban State University, 149 Stavropol’skaya St., Krasnodar, 350040, Russia

    Natal’ya M. Gantsgorn

  3. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave, Moscow, 119992, Russia

    Leonid D. Konyushkin

  4. Kuban State Technological University, 2 Moskovskaya St., Krasnodar, 350072, Russia

    Gennady D. Krapivin

Authors
  1. Elena А. Kaigorodova
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  2. Natal’ya M. Gantsgorn
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  3. Leonid D. Konyushkin
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  4. Gennady D. Krapivin
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Corresponding author

Correspondence to Elena А. Kaigorodova.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2019, 55(10), 1098–1103

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Kaigorodova, E.А., Gantsgorn, N.M., Konyushkin, L.D. et al. Synthesis of novel 6-methyl-4-sulfanylfuro[3,4-с]pyridin-3(1H)-ones. Chem Heterocycl Comp 55, 1098–1103 (2019). https://doi.org/10.1007/s10593-019-02584-5

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  • DOI: https://doi.org/10.1007/s10593-019-02584-5

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