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Synthesis of 5-azido-3-nitro-1H-1,2,4-triazole by using a cyanoethyl activating group

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Chemistry of Heterocyclic Compounds Aims and scope

A new method is proposed for the preparation of 5-azido-3-nitro-1H-1,2,4-triazole, based on cyanoethylation of 5-bromo-3-nitro-1H-1,2,4-triazole, nucleophilic substitution of bromide with azide ion, and removal of cyanoethyl protecting group.

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The work was performed with financial support from the Russian Foundation for Basic Research (project 17-03-00566-а).

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  1. Saint Petersburg State Institute of Technology (Technical University), 26 Moskovsky Ave, Saint Petersburg, 190013, Russia

    Vladimir V. Tolstyakov

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  1. Vladimir V. Tolstyakov
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Correspondence to Vladimir V. Tolstyakov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2017, 53(6/7), 719–721

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Tolstyakov, V.V. Synthesis of 5-azido-3-nitro-1H-1,2,4-triazole by using a cyanoethyl activating group. Chem Heterocycl Comp 53, 719–721 (2017). https://doi.org/10.1007/s10593-017-2115-8

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  • DOI: https://doi.org/10.1007/s10593-017-2115-8

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