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Synthesis of pyridin-2(1H)-ones by the intramolecular cyclization of amides of β-enamino ketones

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Chemistry of Heterocyclic Compounds Aims and scope

It has been shown that intramolecular cyclization of N-(1-methyl-3-oxobut-1-en-1-yl)phenyl- and -tosylacetamides in basic media lead to 3-phenyl- and 3-tosyl-substituted 4,6-dimethylpyridin-2(1H)-ones.

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Correspondence to A. S. Fisyuk.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1005–1007, July, 2009.

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Goncharov, D.S., Kostuchenko, A.S. & Fisyuk, A.S. Synthesis of pyridin-2(1H)-ones by the intramolecular cyclization of amides of β-enamino ketones. Chem Heterocycl Comp 45, 793–795 (2009). https://doi.org/10.1007/s10593-009-0358-8

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  • DOI: https://doi.org/10.1007/s10593-009-0358-8

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