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4-Hydroxy-2-quinolones 121. Synthesis and biological properties of 1-hydroxy-3-oxo-5,6-dihydro-3h-pyrrolo[3,2,1-ij]quino-line-2-carboxylic acid alkylamides

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A simple method is proposed for preparing 1-hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1-ij]-quinoline-2-carboxylic acid alkylamides. For the case of the secondary butylamide features of the steric structure of the synthesized compounds is discussed. The results of a study of their anti-inflammatory and diuretic activities are presented.

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Authors and Affiliations

  1. National University of Pharmacy, Kharkiv, 61002, Ukraine

    I. V. Ukrainets, N. L. Bereznyakova & E. V. Mospanova

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  1. I. V. Ukrainets
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  2. N. L. Bereznyakova
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  3. E. V. Mospanova
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1015–1022, July, 2007.

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Ukrainets, I.V., Bereznyakova, N.L. & Mospanova, E.V. 4-Hydroxy-2-quinolones 121. Synthesis and biological properties of 1-hydroxy-3-oxo-5,6-dihydro-3h-pyrrolo[3,2,1-ij]quino-line-2-carboxylic acid alkylamides. Chem Heterocycl Compd 43, 856–862 (2007). https://doi.org/10.1007/s10593-007-0136-4

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  • DOI: https://doi.org/10.1007/s10593-007-0136-4

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