Abstract
In this study, gold nanorods-embedded regenerated cellulose (AuNRs/RC) films were fabricated as SERS substrates via a simple vacuum filtration technique, and the effects of different analyte deposition protocols on the SERS performance were investigated. Four different analyte deposition protocols were tested. The experimental results demonstrate that the immersion of a dried AuNRs/RC hydrogel film in an analyte solution protocol outperforms the other deposition protocols by eliciting an excellent SERS activity which is due to an efficient analyte adsorption as well as an increase in the hot spot density. The AuNRs/RC hydrogel film in the I–HF method allows to detect crystal violet (model analyte) and thiram (pesticide) with concentrations as low as 1 attomolar (aM) with a high enhancement factor (EF) of 1.4 × 1013. The present study is conducive to the achievement of an efficient molecule adsorption/coverage on cellulose-based hydrogel surfaces as well as the enhancement of the SERS performance.
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Acknowledgments
This research was supported by the Bio & Medical Technology Development Program of the National Research Foundation (NRF) funded by the Korean government (MSIT) (No. 2021M3A9I5021437) and by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (No. 2018R1D1A1B07047874 and 2020R1C1C1004459).
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Kim, D., Lee, K., Jeon, Y. et al. Plasmonic nanoparticle-analyte nanoarchitectronics combined with efficient analyte deposition method on regenerated cellulose-based SERS platform. Cellulose 28, 11493–11502 (2021). https://doi.org/10.1007/s10570-021-04283-x
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DOI: https://doi.org/10.1007/s10570-021-04283-x