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Predictive value of SYNTAX score II for clinical outcomes in cardiogenic shock underwent primary percutaneous coronary intervention; a pilot study

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Abstract

SYNTAX Score II (SSII) connects clinical variables with coronary anatomy. We investigated the prognostic value of SSII in patients with ST segment elevated myocardial infarction (STEMI) complicated with cardiogenic shock treated with primary percutaneous coronary intervention (PPCI). In this retrospective analysis, we evaluated the in-hospital prognostic impact of SSII on 492 patients with STEMI complicated with cardiogenic shock treated with PPCI. Patients were stratified by tertiles of SSII, in-hospital clinical outcomes were compared between those groups. In-hospital univariate analysis revealed higher rates of in-hospital death for patients with SSII in tertile 3, as compared to patients with SSII in tertile 1 (OR 17.4, 95% CI 10.0–30.2, p < 0.001). After adjustment for confounding baseline variables, SSII in tertile 3 was associated with 6.2-fold hazard of in-hospital death (OR 6.2, 95% CI 2.6–14.1, p < 0.001). SSII in patients with STEMI complicated with cardiogenic shock treated with PPCI provide an independent prognostic marker of in-hospital outcomes. Our data suggests SSII to be a simple, feasible and clinically applicable tool for rapid risk stratification in patients with STEMI complicated with cardiogenic shock treated with PPCI.

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References

  1. Thiele H, Zeymer U, NeumannF J, Ferenc M, Olbrich HG, Hausleiter J, Richardt G, Hennersdorf M, Empen K, Fuernau G, Desch S, Eitel I, Hambrecht R, Fuhrmann J, Böhm M, Ebelt H, Schneider S, Schuler G, Werdan K (2012) for the IABP-SHOCK II Trial Investigators Intraaortic balloon support for myocardial infarction with cardiogenic shock. N Engl J Med 367:1287–1296

    Article  CAS  PubMed  Google Scholar 

  2. Islam MS, Panduranga P, Al-Mukhaini M, Al-Riyami A, El-Deeb M, Rahman SA, Al-Riyami MB (2016) In-hospital outcome of patients with cardiogenic shock complicating acute myocardial infarction: results from royal hospital percutaneous coronary intervention registry, Oman. Oman Med J 31(1):46–51

    Article  PubMed  PubMed Central  Google Scholar 

  3. Wijns W, Kolh P, Danchin N et al (2010) Guidelines on myocardial revascularization. Task force on myocardial revascularization of the European Society of Cardiology (ESC) and the European Association for cardio-thoracic surgery (EACTS). Eur Heart J 31(20):2501–2555

    Article  PubMed  Google Scholar 

  4. Levine GN, Bates ER, Blankenship JC et al (2011) 2011 ACCF/AHA/SCAI Guideline for percutaneous coronary intervention. A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines and the society for cardiovascular angiography and interventions. J Am Coll Cardiol 58(24):e44–122

    Article  PubMed  Google Scholar 

  5. Farooq V, van Klaveren D, Steyerberg EW, Meliga E, Vergouwe Y, Chieffo A, Kappetein AP, Colombo A, Holmes DR Jr, Mack M, Feldman T, Morice MC, Stahle E, Onuma Y, Morel MA, Garcia-Garcia HM, van Es GA, Dawkins KD, Mohr FW, PW Serruys (2013) Anatomical and clinical characteristics to guide decision making between coronary artery bypass surgery and percutaneous coronary intervention for individual patients: development and validation of syntax score ii. The Lancet 381:639–650

    Article  Google Scholar 

  6. Kurniawan E, Ding FH, Zhang Q, Yang ZK, Hu J, Shen WF, Zhang RY (2016) Predictive value of SYNTAX score II for clinical outcomes in octogenarian undergoing percutaneous coronary intervention. J Geriatr Cardiol 13(9):733–739

    PubMed  PubMed Central  Google Scholar 

  7. He J, Zhao H, Yu X, Li Q, Lv S, Chen F, Jiang T SYNTAXScore (2017) SYNTAX Score-II predicts long-term mortality in patients who underwent left mainpercutaneous coronary intervention treated with second-generation drug-eluting stents. Int Heart J 58(3):344–350

    Article  PubMed  Google Scholar 

  8. Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, Gutgesell H, Reichek N, Sahn D, Schnittger I (1989) Recommendations for quantitation of the left ventricle by two dimensional echocardiography. American Society of echocardiography committee on standards, subcommittee on quantitation of two-dimensional echocardiograms. J Am Soc Echocardiogr 2:358–367

    Article  CAS  PubMed  Google Scholar 

  9. Oh JK, Hagler DJ, Cabalka A, Reeder GS, Cetta F Jr, Seward JB (2006) Transesophageal and intracardiac echocardiography. In: Oh JK, Seward JB, Tajik AJ (eds) The echomanual, 3rd edn. Lippincott Williams & Wilkins, Philadelphia, PA, pp 29–58

    Google Scholar 

  10. Cockcroft DW, Gault MH (1976) Prediction of creatinine clearance from serum creatinine. Nephron 16:31–41

    Article  CAS  PubMed  Google Scholar 

  11. Roques F, Michel P, Goldstone AR, Nashef SA (2003) The logistic EuroSCORE. Eur Heart J 24:881–882

    Article  CAS  PubMed  Google Scholar 

  12. Serruys PW, Unger F, Sousa JE et al (2001) Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease. N Engl J Med 344:1117–1124

    Article  CAS  PubMed  Google Scholar 

  13. Sianos G, Morel MA, Kappetein AP, Morice MC, Colombo A, Dawkins K, van den Brand M, Van Dyck N, Russell ME, Mohr FW, Serruys PW (2005) The SYNTAX score: an angiographic tool grading the complexity of coronary artery disease. EuroIntervention 1(2):219–227

    PubMed  Google Scholar 

  14. Velásquez-Rodríguez J, Diez-Delhoyo F, Valero-Masa MJ, Vicent L, Devesa C, Sousa-Casasnovas I, Juárez M, Angulo-Llanos R, Fernández-Avilés F, Martínez-Sellés M (2017) Prognostic impact of age and hemoglobin in acute ST-segment elevation myocardial infarction treated with reperfusion therapy. Am J Cardiol 119: (12):1909–1916

    Article  PubMed  Google Scholar 

  15. Perelshtein Brezinov O, Klempfner R, Zekry SB, Goldenberg I, Kuperstein R (2017) Prognostic value of ejection fraction in patients admitted with acute coronary syndrome: a real world study. Medicine (Baltimore) 96(9):e6226

    Article  Google Scholar 

  16. Valente S, Lazzeri C, Vecchio S, Giglioli C, Margheri M, Bernardo P, Comeglio M, Chiocchini S, Gensini GF (2007) Predictors of in-hospital mortality after percutaneous coronary intervention for cardiogenic shock. Int J Cardiol 114(2):176–182

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Cardiology, Haydarpasa Sultan Abdulhamid Han Training and Research Hospital, 34668, Kadikoy, Istanbul, Turkey

    Mert İlker Hayıroğlu, Muhammed Keskin & Ömer Kozan

  2. Department of Cardiology, Hatay Dortyol State Hospital, Hatay, Turkey

    Ahmet Okan Uzun

  3. Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey

    Emrah Bozbeyoğlu & Özlem Yıldırımtürk

  4. Department of Cardiology, Başkent University Faculty of Medicine, Istanbul, Turkey

    Seçkin Pehlivanoğlu

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  1. Mert İlker Hayıroğlu
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  2. Muhammed Keskin
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  3. Ahmet Okan Uzun
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  4. Emrah Bozbeyoğlu
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  5. Özlem Yıldırımtürk
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  6. Ömer Kozan
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  7. Seçkin Pehlivanoğlu
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Correspondence to Mert İlker Hayıroğlu.

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Hayıroğlu, M.İ., Keskin, M., Uzun, A.O. et al. Predictive value of SYNTAX score II for clinical outcomes in cardiogenic shock underwent primary percutaneous coronary intervention; a pilot study. Int J Cardiovasc Imaging 34, 329–336 (2018). https://doi.org/10.1007/s10554-017-1241-9

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  • DOI: https://doi.org/10.1007/s10554-017-1241-9

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