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Vitamin D and mammographic breast density: a systematic review

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Abstract

Studies suggest a protective relationship between Vitamin D and breast cancer risk. Several studies assessed the association of Vitamin D with mammographic breast density, a known and strong breast cancer risk factor. Understanding the potential role of Vitamin D in the modification of breast density might open new avenues in breast cancer prevention. This systematic review summarizes published studies that investigated the association between Vitamin D and mammographic breast density and offers suggestions for strategies to advance our scientific knowledge.

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Acknowledgments

Dr. Graham Colditz is supported by ACS Clinical Research Professorship. Dr. Bettina Drake is supported by PC081669 from the Department of Defense. Dr. Yaghjyan is supported by Barnes-Jewish Hospital Foundation.

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The authors declare that they have no Conflict of interest.

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  1. Division of Public Health Sciences, Department of Surgery, School of Medicine, Washington University in St. Louis, Campus Box 8100, 660 S. Euclid Avenue, St. Louis, MO, 63110, USA

    Lusine Yaghjyan, Graham A. Colditz & Bettina Drake

  2. Institute for Public Health, Washington University in St. Louis, Campus Box 8100, 660 S. Euclid Avenue, St. Louis, MO, 63110, USA

    Graham A. Colditz

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  1. Lusine Yaghjyan
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  2. Graham A. Colditz
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Correspondence to Lusine Yaghjyan.

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Yaghjyan, L., Colditz, G.A. & Drake, B. Vitamin D and mammographic breast density: a systematic review. Cancer Causes Control 23, 1–13 (2012). https://doi.org/10.1007/s10552-011-9851-3

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