Skip to main content
Log in

Bacterial microsystems and microrobots

  • Published:
Biomedical Microdevices Aims and scope Submit manuscript

Abstract

Microorganisms and specifically motile bacteria have been recently added to the list of micro-actuators typically considered for the implementation of microsystems and microrobots. Such trend has been motivated by the fact these microorganisms are self-powered actuators with overall sizes at the lower end of the micrometer range and which have proven to be extremely effective in low Reynolds number hydrodynamic regime of usually less than 10−2. Furthermore, the various sensors or taxes in bacteria influencing their movements can also be exploited to perform tasks that were previously considered only for futuristic artificial microrobots. Bacterial implementations and related issues are not only reviewed, but this paper also proposes many techniques and approaches that can be considered as building blocks for the implementations of more sophisticated microsystems and microrobots.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  • J.J. Abbott, Z. Nagy, F. Beyeller and B.J. Nelson, IEEE Robot. Autom. Mag., 92–103 (2007)

  • J. Adler, Science 153, 708–716 (1966)

    Article  Google Scholar 

  • J. Adler, Bot. Acta. 101, 93–100 (1988)

    Google Scholar 

  • J. Adler, B. Templeton, J. Gen. Microbiol. 46, 175–184 (1967)

    Article  Google Scholar 

  • J. Adler, W.-W. Tso, Science 184(4143), 1292–1294 (1974)

    Article  Google Scholar 

  • G. Alexandre, I.B. Zhulin, J. Bacteriol. 183, 4681–4686 (2001)

    Article  Google Scholar 

  • W. Alt, J. Math. Biol. 9, 147–177 (1980)

    Article  MathSciNet  MATH  Google Scholar 

  • W. Alt, T. Eisele, R. Schaaf, IMA J. Math. Appl. Med. Biol. 2, 109–129 (1985)

    Article  MathSciNet  MATH  Google Scholar 

  • W. André and S. Martel, IEEE/RSJ Int. Conf. on Intelligent Robots and Systems (IROS), 1335–1340, Beijing, China (2006)

  • W. André, B. Moufarrej and S. Martel, 5th Int. Workshop on Microfactories (IWMF), Besançon, France (2006)

  • W. André and S. Martel, IEEE/ASME Int. Conf. on Advanced Intelligent Mechatronics (AIM), Zürich, Switzerland, (2007)

  • W. André, B. Moufarrej and S. Martel, Int. Symp. on Optomechatronic Technologies (ISOT), Lausanne, Switzerland (2007)

  • L. Angelani, R. Di Leonardo, G. Ruocco, Phys. Rev. Lett. 102, 048104 (2009)

    Article  Google Scholar 

  • V. Arabagi, B. Behkam, E. Cheung, M. Sitti, J. Appl. Phys. 109, 114702 (2011)

    Article  Google Scholar 

  • J.P. Armitage, R. Schmitt, Microbiol. 143, 3671–3682 (1997)

    Article  Google Scholar 

  • J.B. Armstrong, J. Adler and M.M. Dahl, 93, 390–398 (1967)

  • V. Balzani, A. Credi, F.M. Raymo, J. Fraser, Angew. Chem. Int. Ed. 39, 3348–3391 (2000)

    Article  Google Scholar 

  • O. Baracchini, J.C. Sherris, J. Path. Bact. 77, 565 (1959)

    Article  Google Scholar 

  • R. Barak, I. Nur, Y. Okon, Y. Henis, J. Bacteriol. 152, 643–649 (1982)

    Google Scholar 

  • D.A. Bazylinski, R.B. Frankel, Nat. Rev. 2, 217–230 (2004)

    Article  Google Scholar 

  • R.N. Bearon, Phys. Fluids 15, 1552–1563 (2003)

    Article  Google Scholar 

  • R.N. Bearon, T.J. Pedley, Bull. Math. Biol. 62, 775–791 (2000)

    Article  Google Scholar 

  • B. Behkam, M. Sitti, ASME J. Dyn. Syst. Meas. Control. 128(1), 36–43 (2006)

    Article  Google Scholar 

  • B. Behkam, M. Sitti, Appl. Phys. Lett. 90, 023902 (2007)

    Article  Google Scholar 

  • B. Behkam, M. Sitti, Appl. Phys. Lett. 93, 223901 (2008)

    Article  Google Scholar 

  • B. Behkam and M. Sitti, Proc. of the IEEE Int. Conf. on Robotics and Automation (ICRA), 1022–1027 (2009)

  • B. Behkam and M. Sitti, Proc. of the ASME Int. Mech. Eng. Congr., Anaheim, CA, USA, 59621–59626 (2004)

  • B. Behkam and M. Sitti, IEEE/ASME Int. Conf. on Advanced Mechatronics (AIM), Monterey, CA, USA, 37–42 (2005)

  • B. Behkam and M. Sitti, Proc. of the IEEE Eng. in Medicine and Biology Society, (2006b)

  • B. Behkman and M. Sitti, (2008a) Proc. of the IEEE RAS-EMBC Int. Conf. on Biomedical Robotics and Biomechatronics, 753–757 (2008a)

  • H. Berg, Sci. Am. 233, 36–44 (1975)

    Article  Google Scholar 

  • H.C. Berg, Biophys. J. 68, 163s–167s (1995)

    Google Scholar 

  • H.C. Berg, Annu. Rev. Biochem. 72, 19–54 (2003)

    Article  Google Scholar 

  • H. Berg, Curr. Biol. 15, R599–R600 (2005)

    Article  Google Scholar 

  • H.C. Berg, R.A. Anderson, Nature 245, 380–382 (1973)

    Article  Google Scholar 

  • H.C. Berg, D.A. Brown, Nature 239, 500–504 (1972)

    Article  Google Scholar 

  • H. Berg, E. coli in Motion, (Springer-Verlag 2004)

  • H.C. Berg, L. Turner, Nature 278, 349–351 (1979)

    Article  Google Scholar 

  • H.C. Berg, L. Turner, Biophys. J. 58, 919–930 (1990)

    Article  Google Scholar 

  • H.C. Berg, Random Walks in Biology, (Princeton University Press, 1983)

  • C. Bettegowda, L.H. Dang, R. Abrams et al., Proc. Natl. Acad. Sci. U. S. A. 100(25), 15083–15088 (2003)

    Article  Google Scholar 

  • S.A. Biodi, J.A. Quinn, H. Goldfire, AICHE J. 44, 1923–1929 (1998)

    Article  Google Scholar 

  • R.P. Blakemore, Science 190, 377–379 (1975)

    Article  Google Scholar 

  • R.P. Blakemore, Annu. Rev. Microbiol. 36, 217–238 (1982)

    Article  Google Scholar 

  • D.A. Brown, H.C. Berg, Proc. Natl. Acad. Sci. U. S. A. 71, 1388–1392 (1974)

    Article  Google Scholar 

  • H.J. Busscher, A.H. Weerkamp, FEMS Microbiol. Rev. 46, 165–173 (1987)

    Article  Google Scholar 

  • A. Cerf, J.-C. Cau, C. Vieu, Colloids Surf. B: Biointerfaces 65, 285–291 (2008)

    Article  Google Scholar 

  • N.W. Charon, S.T. Goldstein, Annu. Rev. Genet. 36, 47–73 (2002)

    Article  Google Scholar 

  • S. Chattopadhyay, R. Moldovan, C. Yeung, X.L. Wu, Proc. Natl. Acad. Sci. U. S. A. 103(37), 13712–13717 (2006)

    Article  Google Scholar 

  • X. Chen, H. Berg, Biophys. J. 78, 1036–1041 (2000)

    Article  Google Scholar 

  • C. Chen, Q. Ma, W. Jiang, T. Song, Appl. Microbiol. Biotechnol. 90(1), 269–275 (2011)

    Article  Google Scholar 

  • A.T. Chwang, T.Y. Wu, Proc. R. Soc. Lond. Ser. B 178, 327–346 (1971)

    Article  Google Scholar 

  • K.B. Chwanrow, M. Cronin, D. O’Hanlon, G.C. O’Sullivan, M. Tangney, Bioeng. Bugs 1, 385–394 (2010)

    Article  Google Scholar 

  • L.H. Cisneros, R. Cortez, C. Dombrowski, R.E. Goldstein, J.O. Kessler, Exp. Fluids 43, 737–753 (2007)

    Article  Google Scholar 

  • B. Coley, Ann. Surg. 14, 199–220 (1891)

    Article  Google Scholar 

  • H.C. Crenshaw, Bull. Math. Biol. 55, 231–255 (1993)

    MATH  Google Scholar 

  • L.H. Dang, C. Bettegowda, D.L. Huso, K.W. Kinzler, B. Vogelstein, Proc. Natl. Acad. Sci. U. S. A. 98, 15155–15160 (2001)

    Article  Google Scholar 

  • P. Dario, R. Valleggi, M.C. Carroza, M.C. Montesi, M. Cocco, J. Micromech, Microeng. 2, 141–157 (1992)

    Article  Google Scholar 

  • N. Darnton, L. Turner, K. Breuer, H.C. Berg, Biophys. J. 86, 1863–1870 (2004)

    Article  Google Scholar 

  • A.P. Davis, Nature (London) 401, 120–121 (1999)

    Article  Google Scholar 

  • J.G. de la Torre, V.A. Bloomfield, Biophys. J. 20, 49–67 (1977)

    Article  Google Scholar 

  • E. De Robertis, C.A. Peluffo, Proc. Soc. Exp. Biol. Med. 78, 584 (1951)

    Google Scholar 

  • H. Debarros, D.M.S. Esquivel, M. Farina, Sci. Prog. 74, 347–359 (1990)

    Google Scholar 

  • R. Di Leonardo, L. Angelani, D. Dell’Arciprete, G. Ruocco, V. Iebba, S. Schippa, M.P. Conte, F. Mecarini, F. De Angelis, E. Di Fabrizio, Proc. Natl. Acad. Sci. U. S. A. 107, 9541–9545 (2010)

    Article  Google Scholar 

  • W.R. DiLuzio, L. Turner, M. Mayer, P. Garstecki, D.B. Weibel, H.C. Berg, G.M. Whitesides, Nature 435, 1271–1274 (2005)

    Article  Google Scholar 

  • C. Dombrowski, L. Cisneros, S. Chatkaew, R.E. Goldstein, J.O. Kessler, Phys. Rev. Lett. 93, 0981031–0981034 (2004)

    Article  Google Scholar 

  • R. Dreyfus, J. Baudry, M.L. Roper, M. Fermigier, H.A. Stone, J. Bibette, Nature 437(6), 862–865 (2005)

    Article  Google Scholar 

  • K.J. Duffy, P.T. Cummins, R.M. Ford, Biophys. J. 68, 800–806 (1995)

    Article  Google Scholar 

  • D.J. Earl, C.M. Pooley, J.F. Ryder, I. Bredberg, J.M. Yeomans, J. Chem. Phys. 126, 064703 (2007)

    Article  Google Scholar 

  • R. Eckert, Science 176, 473–481 (1972)

    Article  Google Scholar 

  • J. Edd, S. Payen, B. Rubinski, M. Stoller and M. Sitti, Proc. of the IEEE/RSJ Int. Conf. on Intelligent Robots and Systsems, 2583–2588 (2003)

  • R. Fearing, 2nd Int. Symp. On Micromachines and Human Sciences, 1–15 (1991)

  • O. Felfoul, M. Mohammadi, L. Gaboury and S. Martel, Proc. IEEE/RSJ Int. Conf. on Intelligent Robots and Systems (IROS), San Francisco, USA (2011)

  • T. Fijita, T. Kawai, JSME Int. J. Ser. C 44, 952–957 (2001)

    Article  Google Scholar 

  • R.A. Firtel, C.Y. Chung, BioEssays 22, 603–615 (2000)

    Article  Google Scholar 

  • P.R. Fisher, BioEssays 19(5), 397–407 (1997)

    Article  Google Scholar 

  • M. Fletcher, Bacterial adhesion: Molecular and Ecological Diversity. Volume Bacterial Attachment in Aquatic Environments: A Diversity of Surfaces and Ahesion Strategies, (Wiley, 1996)

  • N.S. Forbes, L.L. Munn, D. Fukumura, R.K. Jain, Cancer Res. 63, 5188–5193 (2003)

    Google Scholar 

  • R.B. Frankel, Annu. Rev. Biophys. Bioeng. 13, 85–103 (1984)

    Article  Google Scholar 

  • R.B. Frankel, R.P. Blakemore, J. Magn. Magn. Mater. 15–18(3), 1562–1564 (1980)

    Article  Google Scholar 

  • R.B. Frankel, D.A. Bazylinski, M.S. Johnson, B.L. Taylor, Biophys. J. 73, 994–1000 (1997)

    Article  Google Scholar 

  • P.D. Frymier, R.M. Ford, AICHE J. 43, 1341–1347 (1997)

    Article  Google Scholar 

  • P.D. Frymier, R.M. Ford, P.T. Cummins, Chem. Eng. Sci. 48, 687–699 (1993)

    Article  Google Scholar 

  • P.D. Frymier, R.M. Ford, H.C. Berg, P.T. Cummings, Proc. Natl. Acad. Sci. U. S. A. 92, 6195–6199 (1995)

    Article  Google Scholar 

  • W.C. Fuqua, S.C. Winans, E.P. Greenberg, J. Bacteriol. 176, 269–275 (1994)

    Google Scholar 

  • J.Y. Gannon, Y. Tan, P. Baveye, M. Alexander, Appl. Environ. Microbiol. 57, 2497–2501 (1991)

    Google Scholar 

  • P. Garstecki, P. Tierno, D.B. Weibel, F. Sagues, J. Phys, J. Phys. Condens. Matter 21, 204110 (2009)

    Article  Google Scholar 

  • A. Ghosh, P. Fisher, Nano Letters 9(6), 2243–2246 (2009)

    Article  Google Scholar 

  • A.N. Glagolev, J. Theor. Biol. 82, 171–185 (1980)

    Article  Google Scholar 

  • T. Goto, R. Inaoka, Y. Tokano, JSME Int. J. Ser. C 43(4), 875–881 (2000)

    Article  Google Scholar 

  • E.P. Greenberg, E. Canale-Parola, J. Bacteriol. 132, 356–358 (1977a)

    Google Scholar 

  • E. Greenberg, E. Canale-Parola, J. Bacteriol. 130, 485–494 (1977b)

    Google Scholar 

  • M.J. Gross, B.E. Logan, Appl. Environ. Microbiol. 61, 1750–1756 (1995)

    Google Scholar 

  • G.J. Hancock, Proc. R. Soc. Lond. A 217, 96–121 (1953)

    Article  MathSciNet  MATH  Google Scholar 

  • J. Happel, H. Brenner, Low Reynolds Number Hydrodynamics (Kluwer Academic Publishers, Dordrecht, 1973)

    Google Scholar 

  • M. Hara, A. Yamaki, J. Miyake, Mater. Sci. Eng. C. 17, 107–112 (2001)

    Article  Google Scholar 

  • G. Harkes, J. Dankert, J. Feijen, Appl. Environ. Microbiol. 58, 1500–1505 (1992)

    Google Scholar 

  • H.M. Haruff, J. Munakata-Marr, D.W.M. Marr, Colloids Surf. B: Biointerfaces 27, 189–195 (2002)

    Article  Google Scholar 

  • M. Hermansson, Colloids Surf. B: Biointerfaces 14, 105–119 (1999)

    Article  Google Scholar 

  • J.L.L. Higdon, J. Fluid Mech. 90(4), 685–711 (1979)

    Article  MathSciNet  MATH  Google Scholar 

  • N.A. Hill, T.J. Pedley, Fluid. Dynam. Res. 37, 1–20 (2005)

    Article  MathSciNet  MATH  Google Scholar 

  • A.J.T. Hillesdon, T.J. Pedley, J.O. Kessler, Bull. Math. Biol. 57, 299–344 (1995)

    MATH  Google Scholar 

  • Y. Hiratsuka, M. Miyata, T. Tada, T.Q.P. Uyeda, Proc. Natl. Acad. Sci. U. S. A. 103, 13618 (2006)

    Article  Google Scholar 

  • W. Hirofumi, R.R. Netz, Phys. Rev. Lett. 99, 108102 (2007)

    Article  Google Scholar 

  • M.E.J. Holwill, R.E. Burge, Arch. Biochem. Biophys. 101, 249–260 (1963)

    Article  Google Scholar 

  • T. Honda, K.I. Arai, K. Ishiyama, IEEE Trans. Magn. 32, 5085–5087 (1996)

    Article  Google Scholar 

  • M.M. Hopkins, L.J. Fauci, J. Fluid Mech. 455, 149–174 (2002)

    Article  MATH  Google Scholar 

  • S. Hou, R.W. Larsen, D. Boudko, C.W. Riley, E. Karatan, M. Zimmer, G.W. Ordal, M. Alam, Nature 403, 540–544 (2000)

    Article  Google Scholar 

  • Y. Inoue, C. Lo, H. Fukuoka, H. Takahashi, Y. Sowa et al., J. Mol. Biol. 376, 1251–1259 (2008)

    Article  Google Scholar 

  • K. Ishiyama, K.I. Arai, M. Sendoh, A. Yamazaki, J. Micromechatronics 2, 77–86 (2003)

    Article  Google Scholar 

  • R.E. Johnson, C.J. Brokaw, Biophys. J. 25(1), 113–127 (1979)

    Article  Google Scholar 

  • J. Jones, J. Feick, D. Imoudu, N. Chukwumah, M. Vigeant, O. Velegol, Appl. Environ. Microbiol. 69, 6515–6519 (2003)

    Article  Google Scholar 

  • B. Jucker, H. Harms, S. Hug, A. Zehnder, Colloids Surf. B: Biointerfaces 9, 331–343 (1997)

    Article  Google Scholar 

  • R.W. Kasinskas, N.S. Forbes, Biotech. Bioeng. 94(4), 710–721 (2006)

    Article  Google Scholar 

  • J.B. Keller, S.I. Rubinow, Biophys. J. 16, 151–170 (1976)

    Article  Google Scholar 

  • E. Keller, L. Segel, J. Theor. Biol. 30, 225–234 (1971)

    Article  Google Scholar 

  • J.O. Kessler, Contemp. Phys. 10, 202–210 (1985)

    Google Scholar 

  • E. Khoshbakht Marvi, M. Mohammadi and S. Martel, 12th Int. Conf. on New Actuators (ACTUATOR), Bremen, Germany (2010)

  • M. Kim, K. Breuer, J. Fluids Eng. 129, 319–324 (2007a)

    Article  Google Scholar 

  • M. Kim, K. Breuer, Anal. Chem. 79, 955–959 (2007b)

    Article  Google Scholar 

  • M.J. Kim, K.S. Breuer, Small 4, 111–118 (2008)

    Article  Google Scholar 

  • D.H. Kim, D. Casale, L. Köhidai, M.J. Kim, Appl. Phys. Lett. 94, 163901 (2009)

    Article  Google Scholar 

  • D. Kim, A. Liu and M. Sitti, IEEE/RSJ Int. Conf. in Intelligent Robots and Systems, San Francisco, USA (2011)

  • N.T. Kimura, S. Taniguchi, K. Aoki, T. Baba, Cancer Res. 40, 2061–2068 (1980)

    Google Scholar 

  • D. Koshland, Bacterial chemotaxis as a model behavioral system (Raven, New York, 1980)

    Google Scholar 

  • T. Krell, J. Lacal, F. Munoz-Martinez, J.A. Reyes-Darias, B.H. Cadirci, C. Garcia-Fontana, J.L. Ramos, Environ. Microbiol. 13(5), 1115–1124 (2011)

    Article  Google Scholar 

  • E. Lauga, W.R. DiLuzio, G.M. Whitesides, H.A. Stone, Biophys. J. 90(2), 400–412 (2006)

    Article  Google Scholar 

  • H. Lee, A.M. Purdon, V. Chu, R.M. Westervelt, Nano Letters 4(5), 995–998 (2004)

    Article  Google Scholar 

  • M.J. Lemmon, P. Van Zijl, M.E. Fox, M.L. Mauchline, A.J. Garcia, N.P. Minton, J.M. Brown, Gene Ther. 4(8), 791–796 (1997)

    Article  Google Scholar 

  • J. Lighthill, SIAM Rev. 18, 161–173 (1976)

    Article  MathSciNet  MATH  Google Scholar 

  • S.-C. Liu, N.P. Minton, A.J. Giaccia, J.M. Brown, Gene Ther. 9, 291–296 (2002)

    Article  Google Scholar 

  • E. Lobaton and A. Bayen, Proc. of the Americam Control Conf., New York City, USA (2007)

  • B.E. Logan, Nat. Rev. Microbiol. 7, 375–381 (2009)

    Article  Google Scholar 

  • P.S. Lovely, F.W. Dahlquist, J. Theor. Biol. 50, 477–496 (1975)

    Article  Google Scholar 

  • C.P. Lowe, Future Generat. Comput. Syst. 17, 853–862 (2001)

    Article  MATH  Google Scholar 

  • G. Lowe, M. Meister, H.C. Berg, Nature 325, 637–640 (1987)

    Article  Google Scholar 

  • Z. Lu and S. Martel, The Nanotechnology Conf. and Trade Show (NSTI) Nanotech.., Boston, MA, USA (2006a)

  • Z. Lu and S. Martel, 28th IEEE-EMBS Annual Int. Conf. of the Eng. in Med. and Biol. Soc., New York, USA, 3415–3418 (2006b)

  • Z. Lu and S. Martel, The 14th Int. Conf. on Solid-state Sensors and Actuators, Lyon, France (2007)

  • Z. Lu, R. Denomme and S. Martel, The 11th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences (μTAS), Paris, France, (2007a)

  • Z. Lu, J. El-Fouladi, Y. Savaria and S. Martel, The 11th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences (μTAS), Paris, France (2007b)

  • H. Machemer, R. Eckert, J. Comp. Physiol. 104, 247–260 (1975)

    Article  Google Scholar 

  • R. Macnab, D.E. Koshland, J. Mol. Biol. 85, 399–406 (1974)

    Article  Google Scholar 

  • K. Maeda, Y. Imae, J.I. Shioi, F. Oosawa, J. Bacteriol. 127, 1039–1046 (1976)

    Google Scholar 

  • Y. Magariyama, S. Kudo, Biophys. J. 83, 733–739 (2002)

    Article  Google Scholar 

  • N.S. Malvankar, D.R. Lovley, Microbial Nanowires: A New Paradigm for Biological Electron Transfer and Bioelectronics, ChemSusChem. 5(6), 1039–1046 (2012)

  • S. Martel, Method of controlling magnetotactic bacteria, US Provisonal Patent Application No. 60/576,609 (2004)

  • S. Martel, The First IEEE/RAS-EMBS Int. Conf. on Biomed. Robotics and Biomechatronics, 829–834 (2006a)

  • S. Martel, Method and system for controlling micro-objects or micro-particles, Patent Application Publication, US 2006/0073540 A (2006b)

  • S. Martel, Proc. of the Int. Conf. on Microtechnologies in Medicine and Biology, Okinawa, Japan, 89–92 (2006c)

  • S. Martel, 2nd ASM/IEEE EMBS Conf. on Bio, Micro and Nanosystems, San Francisco, CA (2006d)

  • S. Martel and W. André, Int. Advanced Robotics Programme (IARP), Paris, France (2006)

  • S. Martel, C. Tremblay, S. Ngakeng, G. Langlois, Appl. Phys. Lett. 89, 233804–233806 (2006)

    Article  Google Scholar 

  • S. Martel, 16th European Microelectronics and Packaging Conference (EMPC), Oulu, Finland (2007)

  • S. Martel and M. Mohammadi, The 11th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences (μTAS), Paris, France (2007)

  • S. Martel, O. Felfoul and M. Mohammadi, The 2nd IEEE RAS/EMBS Int. Conf. on Biomedical Robotics and Biomechatronics (BioRob), Scottsdale, AZ, USA (2008)

  • S. Martel and M. Mohammadi, Swarm of bacteria builds tiny pyramid, http://www.youtube.com/watch?v=fCSOdQK5PIY (2009)

  • S. Martel, M. Mohammadi, O. Felfoul, Z. Lu, P. Pouponneau, Int. J. Robot. Res. 28(4), 571–582 (2009)

    Article  Google Scholar 

  • S. Martel, Int. Symp. on Experimental Robotics (ISER), New Delhi, India (2010)

  • S. Martel and M. Mohammadi, Proc. of the IEEE Int. Conf. on Robotics and Automation (ICRA), Anchorage, Alaska, USA (2010)

  • S. Martel, M. Mohammadi and N. Mokrani, ASME First Global Congress on NanoEngineering for Medicine and Biology (NEMB), Houston, TX, USA (2010)

  • S. Martel, ASME Int. Manufacturing Science and Eng. Conf., Corvalis, OR, USA (2011)

  • S. Martel et al., SN-38 (or 5-FU) drug encapsulation in liposomes transported by magnetotactic bacteria for localized colorectal cancer treatment, Quebec Consortium for Drug Discovery (CQDM) (2011)

  • L. Maurer, E. Yohannes, S. Bondurant, M. Radmacher, J. Slonczewski, J. Bacteriol. 187, 304–319 (2005)

    Article  Google Scholar 

  • J.W. McClaine, R.M. Ford, Appl. Environ. Microbiol. 68, 1280–1289 (2002a)

    Article  Google Scholar 

  • J.W. McClaine, R.M. Ford, Biotech. Bioeng. 78, 179–189 (2002b)

    Article  Google Scholar 

  • S. McEldowney, M. Fletcher, Appl. Environ. Microbiol. 52, 460–465 (1986)

    Google Scholar 

  • M. Meister, G. Lowe, H.C. Berg, Cell 49, 643–650 (1987)

    Article  Google Scholar 

  • B.A. Mello, Y. Tu, Biophys. J. 84, 2943–2956 (2003)

    Article  Google Scholar 

  • N. Mokrani, M. Mohammadi and S. Martel, The 5th Int. Conf. on Microtech. in Med. and Biol. (MMB) Conf., Quebec City, Canada (2009)

  • N. Mokrani, O. Felfoul, F. Afkhami Zarreh, M. Mohammadi, R. Aloyz, G. Batist and S. Martel, 32nd Annual Int. Conf. of the IEEE Eng. in Medicine and Biology Society, Buenos Airos, Argentina (2010)

  • S.D. Muller, J. Marchetto, S. Airaghi and P. Koumoutsakos, IEEETrans. on IEEE Trans. Evol. Comput. 6(1), (2002)

  • S. Nasseri, N. Phan-Thien, Comput. Mech. 20, 267–271 (1997)

    Article  MATH  Google Scholar 

  • H.C. Nauts, W.E. Swift, B.L. Coley, Cancer Res. 6, 205–216 (1946)

    Google Scholar 

  • S. Nikhil et al. Nature Nanotechnology. 6, 573–579 (2011)

  • P.B. Noble, M. Levine, Computer-Assisted Analyses of Cell Locomotion and Chemotaxis (CRC Press, Boca Raton, 1986)

    Google Scholar 

  • R. Nossal, J. Stat. Phys. 30, 391–399 (1983)

    Article  Google Scholar 

  • H.G. Othmer, T. Hillen, SIAM J. Appl. Math. 62, 1222–1250 (2002)

    Article  MathSciNet  MATH  Google Scholar 

  • J. Palomar, A. Leranov, M. Vinas, Microbios 81, 107–113 (1995)

    Google Scholar 

  • J.S. Parkinson, J. Bacteriol. 135, 45–53 (1978)

    Google Scholar 

  • J.S. Parkinson, Symp. Soc. Gen. Microbiol., Cambridge (1981)

  • J.M. Pawelek, K.B. Low, D. Bermudes, Lancet Oncol. 4, 548–556 (2003)

    Article  Google Scholar 

  • T.J. Pedley, J.O. Kessler, Annu. Rev. Fluid Mech. 24, 313–358 (1992a)

    Article  MathSciNet  Google Scholar 

  • T.J. Pedley, J.O. Kessler, Sci. Prog. 76, 105–123 (1992b)

    Google Scholar 

  • N. Phan-Thien, T. Tran-Cong, M. Ramia, J. Fluid Mech. 184, 533–549 (1987)

    Article  Google Scholar 

  • N.W. Preston, H.B. Maitland, J. Gen. Microbiol. 7, 117 (1952)

    Article  Google Scholar 

  • E.M. Purcell, Am. J. Phys. 45, 3–11 (1976)

    Article  Google Scholar 

  • E.M. Purcell, Proc. Natl. Acad. Sci. 94, 11307–11311 (1997)

    Article  Google Scholar 

  • M. Ramia, Biophys. J. 60, 1057–1078 (1991)

    Article  Google Scholar 

  • M. Ramia, D.L. Tullock, N. Phan-Thien, Biophys. J. 65, 755–778 (1993)

    Article  Google Scholar 

  • J.S. Rathore, N.N. Sharma, ASME J. Nanotech. Eng. Med. 1, 031001 (2010)

    Article  Google Scholar 

  • D.R. Repaske, J. Adler, J. Bacteriol. 145, 1196–1208 (1981)

    Google Scholar 

  • H. Rijnaarts, W. Norde, E. Bouwer, J. Lyklema, A. Zehnder, Colloids Surf. B: Biointerfaces 4, 5–22 (1995)

    Article  Google Scholar 

  • M.A. Rivero, R.T. Tranquillo, H.M. Buettner, D.A. Lauffenburger, Chem. Eng. Sci. 44, 2881–2897 (1989)

    Article  Google Scholar 

  • A.M. Roberts, J. Theor. Biol. 27, 97–106 (1970)

    Article  Google Scholar 

  • M. Rosenberg, Appl. Environ. Microbiol. 42, 375–377 (1981)

    Google Scholar 

  • B. Rowan, M. Wheeler, R. Crooks, Langmuir 18, 9914–9917 (2002)

    Article  Google Scholar 

  • W.S. Ryu, R.M. Berry, H.C. Berg, Nature 403, 444–447 (2000)

    Article  Google Scholar 

  • S. Saeidlou, G. Bringout, C. Dubois, and S. Martel, Fourth Int. ICST Conf. on Nano-Networks (Nano-Net), Luzern, Switzerland (2009)

  • M. Salerno, B. Logan, D. Velegol, Langmuir 20, 10625–10629 (2004)

    Article  Google Scholar 

  • A.D. Samuel, H.C. Berg, Biophys. J. 71, 918–923 (1996)

    Article  Google Scholar 

  • W.R. Schneider, R.N. Doetsch, J. Bacteriol. 117, 696–701 (1974)

    Google Scholar 

  • M.J. Schnitzer, S.M. Block, H.C. Berg, E.M. Purcell, Symp. Soc. Gen. Microbiol. 46, 15–34 (1990)

    Google Scholar 

  • D. Schüler, FEMS Microbiol. Rev. 32(4), 654–672 (2008)

    Article  Google Scholar 

  • T. Schweinitzer, C. Jesenhans, Arch. Microbiol. 192(7), 507–520 (2010)

    Article  Google Scholar 

  • J.W. Shaevitz, J.Y. Lee, D.A. Fletcher, Cell 122(6), 941–945 (2005)

    Article  Google Scholar 

  • N.N. Sharma, R.K. Mittal, Int. J. Smart Sens. Intell. Syst. 1(1), 87–109 (2008)

    MATH  Google Scholar 

  • E. Shechter and S. Martel, The 5th Int. Conf. on Microtech. in Med. and Biol. (MMB) Conf., Quebec City, Canada (2009)

  • E. Shechter and S. Martel, IEEE/ASME Int. Conf. on Advanced Intelligent Mechatronics (AIM), Montréal, Canada (2010)

  • J.C. Sheeris, N.W. Preston, J.G. Shoesmith, J. Gen. Microbiol. 16, 86 (1957)

    Article  Google Scholar 

  • W. Shi, B.A.D. Stocker, J. Adler, J. Bacteriol. 178, 1113–1119 (1996)

    Google Scholar 

  • J. Shioi, R.C. Tribhuwan, S.T. Berg, B.L. Taylor, J. Bacteriol. 170, 5507–5511 (1988)

    Google Scholar 

  • J.G. Shoesmith, J. Gen. Microbiol. 22, 528–535 (1960)

    Article  Google Scholar 

  • M.A. Sleigh, Protoplasma 164, 45–53 (1991)

    Article  Google Scholar 

  • L. Snyder, W. Champness, Molecular Genetics of Bacteria, 3rd edn. (ASM Press, Washington, DC, 2007)

    Google Scholar 

  • A. Sokolov, I. Aranson, J. Kessler, R. Goldstein, Phys. Rev. Lett. 98, 1591021–1591024 (2007)

    Article  Google Scholar 

  • A. Sokolov, M.M. Apodaca, B.A. Grzybowski, I.S. Aranson, Proc. Natl. Acad. Sci. U. S. A. 107(3), 969–974 (2010)

    Article  Google Scholar 

  • R. Soong, D. Bachand, H.P. Neves, A.G. Olkhovets, H.G. Craighead, C.D. Montemagno, Science 290, 1555–1558 (2000)

    Article  Google Scholar 

  • P.A. Spiro, J.S. Parkinson, H.G. Othmer, Proc. Natl. Acad. Sci. U. S. A. 94, 7263–7278 (1997)

    Article  Google Scholar 

  • A.M. Spormann, R.S. Wolfe, FEMS Microbiol. Lett. 22, 171–177 (1984)

    Article  Google Scholar 

  • T.N. Stanbridge, N.W. Preston, J. Gen. Microbiol. 55, 29–36 (1969)

    Article  Google Scholar 

  • E. Steager, C. Kim, J. Patel, S. Bith, C. Naik, L. Reber, M. Kim, Appl. Phys. Lett. 90, 263901–263903 (2007)

    Article  Google Scholar 

  • E.B. Steager, M.S. Sakar, D.H. Kim, V. Kumar, G.J. Pappas, M.J. Kim, J. Micromech. Microeng. 21, 035001 (2011)

    Article  Google Scholar 

  • B.L. Taylor, D.E. Koshland, J. Bacteriol. 123, 557–569 (1975)

    Google Scholar 

  • B.L. Taylor, I.B. Zhulin, Mol. Microbiol. 28, 683–690 (1998)

    Article  Google Scholar 

  • B.L. Taylor, I.B. Zhulin, M.S. Johnson, Annu. Rev. Microbiol. 53, 103–128 (1999)

    Article  Google Scholar 

  • J.F. Toso, V.J. Gill, P. Hwu, F.M. Marincola, N.P. Restifo, D.J. Schwartzentruber, R.M. Sherry, S.L. Topalian, J.C. Yang, F. Stock, L.J. Freezer, K.E. Morton, C. Seipp, L. Haworth, S. Mavroukakis, D. White, S. MacDonald, J. Mao, M. Sznol, S.A. Rosenberg, J. Clin. Oncol. 20, 142–152 (2002)

    Article  Google Scholar 

  • S. Tottori, L. Zhang, F. Qiu, K.K. Krawczyk, A. Franco-Obregon, B.J. Nelson, Adv. Mater. 24(6), 816–816 (2012)

    Google Scholar 

  • S. Trachtenberg, D. Fishelov, M. Ben-artzi, Biophys. J. 85, 1345–1357 (2003)

    Article  Google Scholar 

  • R. Tranquillo, D. Lauffenburger, J. Math. Biol. 25, 229–262 (1987)

    Article  MathSciNet  MATH  Google Scholar 

  • W. Trimmer and R. Jebens, IEEE Int. Conf. on Robotics and Automation, Scottsdale, AZ, USA, 1547–1552 (1989)

  • S. Tsuneda, H. Aikawa, H. Ayashi, A. Yuasa, A. Hirata, FEMS Microbiol. Lett. 223, 287–292 (2003)

    Article  Google Scholar 

  • H. Van der Mei, M. Cown, M. Genet, P. Rouxhet, H. Busscher, Can. J. Microbiol. 38, 1033–1041 (1992)

    Article  Google Scholar 

  • H. Van der Mei, R. Bos, H. Busscher, Colloids Surf. B: Biointerfaces 11, 213–221 (1998)

    Article  Google Scholar 

  • M. van Loosdrecht, J. Lyklema, W. Norde, G. Schraa, A. Zehnder, Appl. Environ. Microbiol. 53, 1893–1897 (1987)

    Google Scholar 

  • M.C. van Loosdrecht, M.C.M.J. Lyklema, A.J.B. Zehnder, Microb. Ecol. 17, 1–15 (1989)

    Article  Google Scholar 

  • M.C. van Loosdrecht, M.C.M.J. Lyklema, A.J.B. Zehnder, Aquat. Sci. 52, 103–114 (1990)

    Article  Google Scholar 

  • J. Van Oss, Cell Biophys. 14, 1–16 (1989)

    Google Scholar 

  • C.A. Voigt, Curr. Opin. Biotechnol. 17, 548–557 (2006)

    Article  Google Scholar 

  • D. Weibel, P. Garstecki, D. Ryan, W.R. DiLuzio, M. Mayer, J.E. Seto, G.M. Whitesides, Proc. Natl. Acad. Sci. 102, 11963–11967 (2005)

    Article  Google Scholar 

  • L.E. Weiss, J.P. Badalamenti, L.J. Weaver, A.R. Tascone, P.S. Weiss, T.L. Richard, P.C. Cirino, Biotechnol. Bioeng. 100, 1251–1255 (2008)

    Article  Google Scholar 

  • A.T. Willis, Anaerobic Bacteriology in Clinical Medicine (Butterworth, London, 1960), p. 40

    Google Scholar 

  • H. Winet, S.R. Keller, J. Exp. Biol. 65, 577–602 (1976)

    Google Scholar 

  • A.J. Wolfe, M.P. Conley, T.J. Kramer, H.C. Berg, J. Bacteriol. 169, 1878–1885 (1987)

    Google Scholar 

  • L.S. Wong, M.S. Johnson, I.B. Zhulin, B.L. Taylor, J. Bacteriol. 177, 3985–3991 (1995)

    Google Scholar 

  • J. Yang, C.W. Wolgemuth, G. Huber, Phys. Rev. Lett. 102, 218102 (2009)

    Article  Google Scholar 

  • R. Yasuda, H. Noji, K. Kinosita, M. Yoshida, Cell 93(7), 1117–1124 (1998)

    Article  Google Scholar 

  • K. Yazawa, M. Fujimori, T. Nakamura et al., Breast Canc. Res. Treat. 66, 165–170 (2001)

    Article  Google Scholar 

  • P. Yongxin, W. Lin, L. Jinhua, T. Lanxiang, D. Chenglong, L. Qingsong, Z. Rixiang, M. Winklhofer, N. Petersen, Biophys. J. 97, 986–991 (2009)

    Article  Google Scholar 

  • L. Zhang, J.J. Abbott, L. Dong, B.E. Kratochvil, H. Zhang, K.E. Peyer and B.J. Nelson, IEEE/RSJ Int. Conf. on Intelligent Robots and Systems, St. Louis, USA, 1401–1401 (2009b)

  • L. Zhang, J.J. Abbott, L.X. Dong, B.E. Kratochvil, D.J. Bell, B.J. Nelson, Appl. Phys. Lett. 94, 064107 (2009)

    Article  Google Scholar 

  • L. Zhang, K.E. Peyer, B.J. Nelson, Lab Chip 10, 2203–2215 (2010)

    Article  Google Scholar 

  • I.B. Zhulin, J.P. Armitage, J. Bacteriol. 175, 952–958 (1993)

    Google Scholar 

  • I.B. Zhulin, V.A. Bespalov, M.S. Johnson, B.L. Taylor, J. Bacteriol. 178, 5199–5204 (1996)

    Google Scholar 

  • A. Zita, M. Hermansson, Appl. Environ. Microbiol. 60, 3041–3048 (1987)

    Google Scholar 

Download references

Acknowledgments

Dr. Mohammadi from the NanoRobotics Laboratory at EPM is acknowledged for its help in the literature review process. During the writing of this paper, the author was supported by the Research Chair of École Polytechnique in Nanorobotics and a Discovery Grant from the National Research Council of Canada (NSERC).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sylvain Martel.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Martel, S. Bacterial microsystems and microrobots. Biomed Microdevices 14, 1033–1045 (2012). https://doi.org/10.1007/s10544-012-9696-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10544-012-9696-x

Keywords

Navigation