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Enhanced transesterification of ethyl ferulate with glycerol for preparing glyceryl diferulate using a lipase in ionic liquids as reaction medium

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Abstract

Glyceryl diferulate (DFG) is a water-soluble ester of ferulic acid. A novel ionic liquid (IL) system for enzymatic transesterification of ethyl ferulate (EF) with glycerol to produce DFG was developed. Of three ILs with different anions (BF4 −, PF6 − and TF2N−) and cations (BDMIM, OMIM, HMIM, BMIM, and EMIM), EMIMTF2N proved the best using a commercial lipase. It had a significant protective effect against thermal inactivation of the enzyme. High EF conversion (~100 %) and DFG yield (45 %) were achieved using 45 mg enzyme/ml; temperature, 70 °C; reaction time, 12 h.

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Acknowledgments

The work was supported by the National Natural Science Foundation of China (31101301), the Doctoral Foundation of Henan University of Technology (2009BS022), and the Science Research Foundation of Henan University of Technology Graduate Education Innovation Project (11YJCX19).

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Authors and Affiliations

  1. Lipid Technology and Engineering, School of Food Science and Engineering, Henan University of Technology, Lianhua Road, Zhengzhou, 450001, Henan, People’s Republic of China

    Shangde Sun, Fei Qin, Yanlan Bi, Jingnan Chen, Guolong Yang & Wei Liu

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  1. Shangde Sun
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  2. Fei Qin
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  3. Yanlan Bi
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  4. Jingnan Chen
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  5. Guolong Yang
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  6. Wei Liu
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Correspondence to Shangde Sun.

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Sun, S., Qin, F., Bi, Y. et al. Enhanced transesterification of ethyl ferulate with glycerol for preparing glyceryl diferulate using a lipase in ionic liquids as reaction medium. Biotechnol Lett 35, 1449–1454 (2013). https://doi.org/10.1007/s10529-013-1222-6

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  • DOI: https://doi.org/10.1007/s10529-013-1222-6

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