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Phospholipase D and its application in biocatalysis

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Abstract

Phospholipase D (PLD) from plants or microorganisms is used as biocatalyst in the transformation of phospholipids and phospholipid analogs in both laboratory and industrial scale. In recent years the elucidation of the primary structure of many PLDs from several sources, as well as the resolution of the first crystal structure of a microbial PLD, have yielded new insights into the structural basis and the catalytic mechanism of this catalyst. This review summarizes some new results of PLD research in the light of application.

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Authors and Affiliations

  1. Department of Biochemistry/Biotechnology, Martin-Luther University Halle-Wittenberg, D-06120, Halle, Germany

    Renate Ulbrich-Hofmann & Alexandra Lerchner

  2. Department of Cell and Molecular Biology of Drugs, Faculty of Pharmacy, Comenius University, Kalinciakova 8, SK-83232, Bratislava, Slovakia

    Marek Oblozinsky & Lydia Bezakova

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  1. Renate Ulbrich-Hofmann
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  3. Marek Oblozinsky
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  4. Lydia Bezakova
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Correspondence to Renate Ulbrich-Hofmann.

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Ulbrich-Hofmann, R., Lerchner, A., Oblozinsky, M. et al. Phospholipase D and its application in biocatalysis. Biotechnol Lett 27, 535–544 (2005). https://doi.org/10.1007/s10529-005-3251-2

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